Month: December 2024

Creating induced pluripotent stem cells (iPSCs) causes mutant mitochondrial populations to change, and researchers have investigated this phenomenon more thoroughly. Easy to mutate Why We Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells and cause increasing levels of...

BioAge Labs, Inc. ("BioAge"), a clinical-stage biopharmaceutical company developing therapeutic product candidates for metabolic diseases by targeting the biology of human aging, today announced a multi-year research collaboration with Novartis. The collaboration aims to identify and validate multiple novel therapeutic drug targets by investigating the biological mechanisms that drive diseases related to aging and mediate...

A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to be the best lifestyle factor to slow aging and alleviates many aging-associated diseases and molecular changes. We have previously reported that exercise positively impacts cognition...

Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While some senescent cells have been found to have a beneficial effect on wound healing [1], the increase in cellular senescence with age has been suspected...

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair treatment There has been a substantial amount of previous work in restoring hair follicle growth by culturing dermal papilla cells (DPs), which are the mesenchymal...

With the deadline for submissions just around the corner, Jamie Justice, Executive Director of XPRIZE HealthSpan, explains to researchers still on the fence why they should contact her team now but also why missing the deadline is not the end of the world. XPRIZE Foundation has been making history for 30 years with dozens of...