Tag: Clinical Trials

Los Angeles-based Pelage Pharmaceuticals has just announced a Phase 2a clinical trial for the treatment of androgenetic alopecia, also known as pattern baldness. It is thought that up to 50% of men experience hair loss as a result of pattern baldness by age 50. In this condition, the normal hair growth cycle is disrupted due...

Reviewers have gone through the latest updates on studies featuring rapamycin and its derivatives in The Lancet Healthy Longevity. Testing a well-known longevity promoter Not many compounds actually extend life in healthy animals, but rapamycin is indeed one of them. These researchers report that its mechanism of action, the mechanistic target of rapamycin (mTOR), is...

A new review authored by three acclaimed geroscientists paints a promising picture of past and ongoing human clinical trials of prospective anti-aging drugs [1]. From worms and mice to humans The biology of aging is an exciting new field, but most of its successes have been in animal models, from the early breakthroughs in yeast...

Researchers publishing in Ageing Research Reviews have conducted a large meta-analysis of papers that document the effects of exercise on cognitive function in healthy people. Not just for established conditions We have previously discussed how, even for healthy people, exercise is associated with improved biomarkers of health. These researchers have done something similar, although rather...

In a recent paper, researchers reviewed the literature for human clinical trials that address NMN's safety and anti-aging effects [1]. The roles of NAD+ and NMN in aging Nicotinamide mononucleotide (NMN): Benefits and Side EffectsNicotinamide mononucleotide (NMN) is a precursor of the coenzyme NAD+, which serves critical functions in our cells. The decline of NAD+...

Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes drug Long periods of disuse cause muscles to atrophy and accelerate the age-related muscle wasting known as sarcopenia [1]. Strength training is the accepted treatment...