Tag: Drug Discovery

The authors of a recent review analyzed the results of 14 studies that included 139 million people to identify patterns that connect dementia risk to commonly used medications [1]. Finding a new purpose Despite its prevalence in the elderly population, there is a lack of effective clinical treatments for dementia, and there is ongoing research...

In Aging, researchers from Spain and Luxembourg have described the creation of Single-cell RNA-seq Investigation of Rejuvenation Agents and Longevity (SINGULAR), an atlas for cellular rejuvenation that describes how interventions affect individual cells. Computational biology might light up a better path These researchers begin this paper by describing the problems with current interventions against the...

New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what's easiest to target Why We Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...

According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1]. From folk medicine to modern science Traditional and folk medicines offer many botanical extracts that can be tested by modern science for their medicinal properties and...

After Oculus was sold to Facebook for two billion dollars a decade ago, Michael Antonov, one of the founders, could have become a major tech investor, a popular podcaster with his own mega-theory of everything, a hedonist, or all of the above. Instead, he gravitated towards the emerging field of longevity biotech, where the uncertainties...

The authors of a recent paper published in GeroScience used an alternative statistical test to reanalyze data from the Interventions Testing Program and identified additional life‑extending compounds [1]. The crucial step of data analysis A typical biological experiment can be divided into three stages: planning, executing, and results analysis. The last part can be done...