Tag: Epigenetic Alterations

A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to be the best lifestyle factor to slow aging and alleviates many aging-associated diseases and molecular changes. We have previously reported that exercise positively impacts cognition...

Today, we bring you a selection of presentations from the annual conference organized by the Gerontological Society of America. Most of our savvy readers, if asked to name the biggest gerontology conference, would probably go with the venerable ARDD in Copenhagen or the new favorite, Hevolution Foundation’s Healthspan Summit in Riyadh. Yet, both pale in...

Researchers have reported in Aging Cell that injecting specific one-carbon metabolites into the hippocampus can rejuvenate its cells. A small molecule approach Why We Age: Epigenetic AlterationsEpigenetic alterations are age-related changes in gene expression that harm the fundamental functions of cells and increase the risk of cancer and other age-related diseases. One of the proposed...

Juan José Alba-Linares and his research team have published a preprint study that examined why different animals age at different rates. They found that epigenetic changes over time could explain why some animals live longer and estimated an upper limit for mammalian lifespan [1]. A problem of noise Why We Age: Epigenetic AlterationsEpigenetic alterations are...

In Stem Cell Reports, researchers have described how cell subpopulations and division affect the results of epigenetic clocks. Good, but never perfect Epigenetic Clocks - What are they?An epigenetic clock is a biochemical test that uses DNA methylation levels and accumulation of methyl groups on DNA to determine biological age. There are many different kinds...

In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed The natural human genome has a large number of artifacts left over from ancient viral infections along with pieces of DNA that transpose themselves into...