Tag: Extracellular Vesicles

In Aging, researchers have reported that deriving extracellular vesicles from mesenchymal stromal cells (MSCs) in fat tissue has beneficial effects in models of osteoarthritis. Which source to use? Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are...

A novel therapy based on induced neuronal stem cells shows promise in a mouse model of Alzheimer’s disease – and it can be administered intranasally [1]. Who needs cells? Stem cell therapies have made great strides in recent decades. They have been successfully employed against numerous diseases, from cancer to osteoarthritis. However, storing, transporting, and...

Researchers have filled extracellular vesicles (EVs) with micro-RNA that is effective against liver fibrosis in mice and published their breakthrough in Aging Cell. The cellular postal service EVs, which cells use to send chemical messages and packages to one another, are significantly affected by aging to the point that they have been used as biomarkers...

Tiny bubbles that cells use to communicate with each other prolonged lifespan and reversed numerous aging phenotypes when taken from young mice and injected into old ones, even though the treatment started late in life [1]. The tiny messengers For millennia, humans credited young blood with rejuvenating qualities. This belief caused legendary and historic rulers...

In the Journal of Nanobiotechnology, researchers have found that embedding microvesicles in a slow-release hydrogel may be an effective treatment for osteoarthritis. A line of inquiry begins to bear fruit Researchers have repeatedly found that the extracellular vesicles (EVs) released by stem cells, particularly mesenchymal stem cells (MSCs), are the main drivers behind the effectiveness...

Researchers publishing in ACS Nano have described how culturing stem cells on nanogratings instead of flat substrates changes the effects of the extracellular vesicles (EVs) they send, potentially paving the way to a new system of therapies. When signaling is critical Many of the effects of stem cells can be traced back to the EVs,...