Tag: João Pedro de Magalhães

João Pedro de Magalhães, professor at the University of Birmingham, is known as a prominent geroscientist who has been in the field forever, enriching it with top-tier research. He is also a skilled longevity advocate who has long taken interest in the ethics of longevity, first offering his perspective as far back as 2003. Prof....

A prominent geroscientist suggests that more than 100 million years of saurian domination might have deprived mammals of longevity-promoting traits that are found in today’s reptiles [1]. The longevity bottleneck Today, mammals rule the world, but, sadly, we only have an average of 80 years to enjoy our superiority. That's a lot by mammalian standards:...

In a preprint paper published on bioRxiv, researchers including João Pedro de Magalhães have gotten a glimpse at how stemness declines across tissues with aging. Using AI to get a grasp on stemness Stem Cell ExhaustionStem cell exhaustion is the age-related deficiency of stem cells. This particular hallmark is directly responsible for many of the...

Professor João Pedro de Magalhães leads the Genomics of Ageing and Rejuvenation Lab at the Institute of Inflammation and Ageing in the University of Birmingham. He is also CSO of YouthBio Therapeutics, a US-based biotech company that develops rejuvenation gene therapies based on partial reprogramming by Yamanaka factors. Last year, he co-authored The hoverfly and...

The hallmarks of aging, as presented in a 2013 paper [1], have been useful but do not provide a genuine explanatory paradigm, argue David Gems of University College London and João Pedro de Magalhães of the University of Liverpool in a pre-print paper [2]. They propose that biogerontology would benefit from replacing the hallmarks with...

Dr. João Pedro de Magalhães is a Professor at the University of Liverpool, England, where he studies aging and longevity at the genetic level, and he is also an affiliate Principal Investigator in the Neuroendocrinology and Aging Group at the University of Coimbra, Portugal. Dr. de Magalhães has built the Human Ageing Genomic Resources (HAGR),...