Tag: Macrophages

In Nature Aging, researchers have discovered how growth differentiation factor 3 (GDF3), a cytokine that increases with aging, is related to more inflammatory macrophages in older animals. Fat and inflammation We have recently reported on a potential treatment for visceral fat, as this kind of fat is known to generate health problems, including an increase...

A new study ties the disappearance of capillary-associated macrophages to age-related vascular degeneration in the skin. Boosting their function with a growth factor offers a possible avenue for anti-aging interventions [1]. Macrophages, capillaries, and skin aging Skin aging might not be the most dangerous aspect of aging, but it certainly is one of the most...

In Nature Aging, researchers have identified and categorized several macrophage subtypes, including a subtype that appears with aging and another that manages nerve function. Not all macrophages follow the same rules Chronic InflammationChronic inflammation refers to a persistent, low-grade buzz of immune activity that settles into the body without the drama of an infection or...

In Aging Cell, researchers have linked macrophage senescence to the failure of new blood vessel formation, finding a key target that might make it easier to treat arterial clogs. Macrophages can impair blood vessel formation Heart attack and stroke are not the only problems caused by clogged and unusable blood vessels; when this occurs in...

In Aging, researchers have published a new study on a tool meant for analyzing macrophage senescence along with differences between inflammaging and regular inflammation. Macrophages are driven to senescence Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead,...

A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound Corylin is a compound that was first discovered in Psoralea corylifolia, a plant commonly used in Chinese traditional medicine. This is far from the first...