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Tag: p53

A researcher holding a lab rat.
In Aging Cell, researchers have published their findings that exosomes, which we have previously reported to extend the lives of mice, also extend the lives of rats. Known to be effective Exosomes, a subset of extracellular vesicles (EVs), can be visualized as messages and packages that cells send to one another. Along with lifespan studies,...
Greenland Shark
Scientists have compiled the most complete genome ever of the Greenland shark, an exceptionally long-lived species. Living up to 400 years probably has a lot to do with superior DNA repair mechanisms. Methuselahs of the sea Greenland sharks, giant, slow-moving abyss dwellers, hold the title of the longest-lived vertebrate. While estimating a wild species’ maximum...
Human Heart
Researchers have found that the protein fortilin, which is abundant in the heart, protects it from failure by blocking apoptotic activity. This discovery opens new possibilities in treating age-related heart diseases [1]. When your heart fails you As menacing at it sounds, heart failure (HF) does not mean that your heart has completely failed, just...
Antique, complicated clock
Researchers have developed a new transcriptomic aging clock that incorporates information about biological pathways. With this approach, the clock predicts not only age but also how the state of various genetic pathways changes with age, providing insight into the transcriptional changes involved in aging. Time for a new kind of clock In recent years, the...