December 05, 2024
In a study published in Aging Cell, researchers have outlined a relationship between mitochondrial fragmentation in skeletal muscle and the loss of strength with age. Broken power plants Why We Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells...
November 21, 2024
In Aging Cell, researchers have described the specific cell types that give exercise protective effects against motor nerve degeneration. A different level of back problems With aging, the prevalence of nerves connecting to muscle tissue dwindles, a phenomenon known as denervation [1]. This has been linked to a depopulation of the alpha motor neurons in...
August 28, 2024
A recent paper has reported on improving muscle function in aged mice through combined treatment of exercise and the inhibition of NNMT, an enzyme involved in NAD+ metabolism [1]. Age-related muscle loss Muscle loss is a common problem in the aging population. Studies estimate that “after age 50, adults lose approximately 1% of their muscle...
July 30, 2024
In Aging Cell, researchers have published a paper on a cellular energy source that appears to be a key signaling molecule in sarcopenia. A little-explored molecule Sarcopenia, a condition that increases with aging, reduces muscle mass in older people, and leads to a decreased quality of life [1], has been documented to have multiple root...
June 17, 2024
In Aging Cell, researchers have published data on a causal link between brain structure changes and age-related muscle loss (sarcopenia). Not just falls and frailty Sarcopenia is a key reason for the loss of independence among older people. Data on the prevalence of this gradual disorder varies by region and measurement, but some data suggests...
June 06, 2024
Researchers have published a potential new method of treating the age-related muscle loss known as sarcopenia in Aging Cell. A return to NAD+ Nicotinamide Adenine Dinucleotide (NAD): Benefits and ResearchNicotinamide adenine dinucleotide (NAD) is a coenzyme found in all living cells. It is a dinucleotide, which means that it consists of two nucleotides joined through...