Tag: Stem Cells

Creating induced pluripotent stem cells (iPSCs) causes mutant mitochondrial populations to change, and researchers have investigated this phenomenon more thoroughly. Easy to mutate Why We Age: Mitochondrial DysfunctionAs they age, the mitochondria in our cells lose their ability to provide cellular energy and release reactive oxygen species that harm cells and cause increasing levels of...

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair treatment There has been a substantial amount of previous work in restoring hair follicle growth by culturing dermal papilla cells (DPs), which are the mesenchymal...

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction in senescence-associated processes, such as inflammation, fibrosis, oxidative damage, and apoptosis [1]. Increasing healthspan by delaying menopause Aging of the female reproductive system precedes aging...

Scientists have shown that in a direct cellular reprogramming scenario, neurons are produced almost exclusively by a rare subtype of multipotent cells. Their findings, they claim, change our understanding of reprogramming, but not everyone agrees [1]. Direct action In the world of cellular reprogramming, the two most well-known realms are pluripotent reprogramming, in which somatic...

Researchers have discovered a protein that is necessary for proper healing of damaged corneal tissue and that this protein decreases with age. Repairing a shield that is easy to damage The corneal epithelium covers the cornea, which focuses light onto the retina of the eye. Although it fulfills multiple protective functions, this tissue is not...

Experiments in mouse models show the efficacy and safety of mesenchymal stem cell transplantation in treating ovarian aging [1]. Mesenchymal stem cells as a therapy Mesenchymal stem cells (MSCs) are stem cells derived from mesodermal tissue, such as the umbilical cord, umbilical cord blood, the placenta, fat tissue, and bone marrow [2]. MSCs are a...