Tag: TLR4

Researchers have discovered negative ways in which intestinal bacteria change over time, spurring gut inflammation, and introduced older bacteria into a population of younger mice to determine their effects. A well-known link It has been thoroughly documented that gut bacteria have an influence on aging [1], and age-related changes to gut inflammation can lead to...

In a new study, genetic deletion of the TLR4 receptor ameliorated aspects of age-related cognitive decline in naturally aging mice, probably due to decreased inflammation [1]. Taking a toll as we age Toll-like receptor 4 (TLR4) is a member of an ancient, highly evolutionary conserved family of proteins expressed mostly by the cells of the...