December 17, 2024
Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While some senescent cells have been found to have a beneficial effect on wound healing [1], the increase in cellular senescence with age has been suspected...
July 25, 2024
In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The researchers begin this paper by pointing out that injuries to the musculoskeletal system are responsible for over a quarter of the years that elderly people...
January 04, 2023
New research published in Nature has shown that senescent cells hamper muscle regeneration through inflammation and fibrosis [1]. Cellular senescence is one of the hallmarks of aging. However, there is a growing understanding that, just like aging itself, senescence is a complex and heterogeneous phenomenon [2]. Senescent phenotypes differ considerably depending on what causes them...
December 22, 2021
A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration? Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...
October 27, 2021
The latest research out of the Journal of Cell Biology shines a light on why our skin loses its healing abilities as we age. Skin Structure and AgingSkin, as the most readily visible organ of the human body, is one of the first to let us know that we are getting older. Our skin goes...
September 23, 2020
A new study published in Archives of Dermatological Research has shown that a novel microporous membrane can promote the regeneration of healthy human skin. Skin Structure and AgingSkin, as the most readily visible organ of the human body, is one of the first to let us know that we are getting older. Our skin goes...