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November 27, 2024
The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function occurs before a similar decline in other organs. Already in their mid-to-late thirties, women can experience symptoms such as fertility problems or increased frequency of...
November 20, 2024
An analysis of data from over twenty thousand people has indicated that greater dietary diversity is associated with slower biological aging [1]. Your health is what you eat Good dietary habits are linked to many health benefits, and different diets were previously reported to impact the speed of aging and senescence. For example, adherence to...
November 13, 2024
In a new study, researchers tested the impact of the senolytic drug ABT-263 on the reproductive systems of old female mice. ABT-263 treatment did not rescue age-related changes in hormonal levels, further depleted ovarian reserves, and didn’t improve most of the tested signs of reproductive aging [1]. Not created equal Aging doesn’t seem to affect...
November 06, 2024
In a new study, the researchers administered human umbilical cord-derived mesenchymal stem cells (HUCMSCs) to aged mice and observed reduced degeneration in multiple organs, changes to microbial composition, metabolic alterations, improvements in behavior and ability, and reduced fearfulness [1]. Therapeutic potential Earlier this year, we reported on a clinical trial in which administering HUCMSCs reduced...
October 30, 2024
A recent preprint study suggests that a NOVOS supplement can improve healthspan and extend lifespan in male mice [1]. Multiple ingredients, one goal This preprint's authors start by discussing dietary supplements' beneficial effects on lifespan and markers of healthspan in multiple organisms and their possible additive and synergistic effects that result from targeting multiple aging...
October 23, 2024
Investigating the factors involved in skin rejuvenation processes, researchers have identified the role of hyaluronan and proteoglycan link protein 1 (HAPLN1) in restoring collagen and hyaluronic acid in aged skin [1]. The most noticeable sign of aging Skin aging, one of the most visible forms of aging, is influenced by both intrinsic and extrinsic factors....