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January 21, 2025
Researchers have found that kinesin family member 9 (KIF9), a protein that diminishes with aging, is instrumental in allowing cells to consume harmful proteins and fights Alzheimer's in a mouse model. Consuming amyloids before they become a problem What is Autophagy?Autophagy, derived from ancient Greek, means "eating of self". Autophagy is the way cells break...
January 16, 2025
Researchers publishing in Physical Review X have discovered compounds that can double the efficiency of the sirtuin SIRT3 in processing NAD+. Looking for a new way to boost enzymes The researchers begin their paper by noting that most drugs administered to people are geared towards inhibition of particular enzymes in order to treat a disease....
January 13, 2025
Researchers have discovered that intermittent fasting increases myelin in aged mice, leading to better neural function and coordination. Crucial proteins and a well-known intervention Normally, neuronal axons are coated in a protein sheath made of myelin, which is necessary for their proper function [1]. Myelination is most known to be impeded by multiple sclerosis, but...
January 09, 2025
In a journal called Small, researchers have described a new targeting mechanism for delivering senolytic compounds where they need to go. Finding the right nanoparticle Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which they are part; instead, they...
January 06, 2025
In JCI Insight, researchers have explored the possibility of using gene therapy to restore a crucial protein and repair hearing loss. Hearing and its failure In mammals, afferent neurons, which originate from the inner ear, transform received stimuli (sound waves) into electrical signals [1]. This process is known as mechanoelectrical transduction, and a specific myosin,...
January 02, 2025
A team of researchers has outlined a new approach that uses mRNA to prevent senescence and strengthen mesenchymal stem cells (MSCs) against aging before they are transplanted into patients. Stem cells go bad before they can be used The researchers introduce this study by focusing on the translational problems with MSCs, specifically the propensity of...
