Tag: Cellular Senescence

New research in Aging Cell has suggested that targeting senescent cells based on their surface proteins (surfaceome) may be effective in dealing with them. Focusing on what's easiest to target Why we Age: Cellular SenescenceAs your body ages, more of your cells become senescent. Senescent cells do not divide or support the tissues of which...

In a new study, a multi-prong treatment combined with a clever delivery method has shown promise against one of the deadliest cancers [1]. Lethal and barely treatable Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest types of cancer. It is rarely diagnosed early and very aggressive. It also responds poorly to treatment, primarily because...

A researcher publishing in Biogerontology has reviewed the literature on the relationship between cellular senescence and the immune system, finding that dwindling immune surveillance allows senescent cells to accumulate. The immune system needs to be deadly On the cellular level, the bodies of vertebrates are brutal police states. Immune cells report, attack, and kill anything...

According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1]. From folk medicine to modern science Traditional and folk medicines offer many botanical extracts that can be tested by modern science for their medicinal properties and...

In Aging Cell, researchers have published details on the pathway by which a compound commonly found in ketone bodies ameliorates osteoarthritis in a rat model. Chondrocytes are crucial in arthritis The cartilage holding joints together is built and maintained by chondrocytes, which synthesize such necessary proteins as collagen and aggrecan [1]. Unfortunately, the cellular senescence...

In Aging Cell, researchers have published new data on the relationship between senescence and the extracellular matrix in the tendons of older people. Easy to injure, hard to heal The researchers begin this paper by pointing out that injuries to the musculoskeletal system are responsible for over a quarter of the years that elderly people...