Lifespan Research Institute

Category: News

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BioAge Off to a Rapid Start in 2021

BioAge Labs is off to a fast start in 2021, with two drugs in its pipeline now undergoing clinical trials and a third planned to start in the near future.

Priorities

Are There More Urgent Issues Than Aging?

When you discuss any major issue, sooner or later someone will say it: there are more urgent issues than whatever it is you’re advocating for. Sometimes it may be true;

Elderly eyes

FDA-Approved Drug Is a Candidate for Dry AMD Treatment

In a new paper published in Aging, researchers have determined that directly improving autophagy through flubendazole (FLBZ) is potentially useful in treating dry age-related macular degeneration (AMD), a disease that

Depression can potentially accelerate aging.

GrimAge Links Aging and Major Depression

People with major depressive disorder may have a biological age as much as two years greater than their chronological age, according to a new study [1]. The discovery provides a

Mouse brain maze

B-cell Depletion Ameliorates Alzheimer’s in Mice

According to a new study, Alzheimer’s disease is connected to inflammaging, which causes B-cells to change their phenotype and hamper amyloid-β (Aβ) removal [1]. Following successful experiments in vivo, the

Increased Longevity and Overpopulation

Any discussion of rejuvenation biotechnology almost certainly includes the subject of overpopulation and the objection that medical advances that directly address the various processes of aging will lead to an overpopulated world. Such dire

Some people think life extension would lead to resource shortages.

Some Argue that Increased Longevity Would Cause Scarcity

The discussion of increased lifespans through medical and technological methods of addressing the various processes of aging raises the concern that this could lead to a lack of resources and result in conflict and suffering. The argument suggests that we will run out of resources if we develop the technology

A longer life does not have to me more time spent sick or frail if we develop the technology to address the causes of aging.

Some People Worry that Longer Lives Mean Decrepitude

Whenever the topic of increasing human lifespan is discussed, the concern is sometimes raised that a longer life would mean a life spent frail and decrepit. This is sometimes known as the Tithonus error and shows a fundamental misunderstanding of the aims of rejuvenation biotechnology. The

Blood-brain barrier

The Blood-Brain Barrier’s Role in Brain Aging

Research suggests that the degradation of the blood-brain barrier over time is a factor in the development of brain diseases. An organ we don’t want to age As our brains age, we experience memory loss, a decreased ability to multitask, a lower attention span, and slower

Scarring

Drug Allows Healing Without Scars in Mice

Researchers have been trying to find out how to stop the formation of scars for decades, and now, thanks to a new mouse study, they are one step closer. Scars are a fast but poor repair Many of us have scars of one kind or another

Smell of Food

Smelling Food Undermines Dietary Restriction in Nematodes

Experiments by researchers in China and the US have shown that the smell of food is enough to reduce the lifespan gains caused by dietary restriction in nematodes. By unraveling the genetic and neurological network behind this, the team found evidence that the same might hold

BioAge logo

BioAge Off to a Rapid Start in 2021

BioAge Labs is off to a fast start in 2021, with two drugs in its pipeline now undergoing clinical trials and a third planned to start in the near future. Building momentum After a $90 million Series C funding round closed late last year, BioAge has

Qigong practice

Qigong Attenuates Age-Related Cognitive Decline in Trial

Researchers from the University of Hong Kong have found that qigong, an ancient Chinese mind-body practice, improves cognitive abilities, lowers inflammation, and increases the size of the hippocampus in elderly subjects [1]. A value to tradition Scientists agree that if we want to live longer, exercise

Priorities

Are There More Urgent Issues Than Aging?

When you discuss any major issue, sooner or later someone will say it: there are more urgent issues than whatever it is you’re advocating for. Sometimes it may be true; other times, and probably most of the time, it’s a logical fallacy known as appeal to

Elderly crowd

EU Green Paper on Aging Falls Short of the Mark

By the year 2050, one in four Europeans will be aged 65 or over, which presents a number of challenges and possible opportunities for Europe’s rapidly aging society. To this end, the European Commission published the “Green paper on ageing – Fostering solidarity and responsibility between

Elderly eyes

FDA-Approved Drug Is a Candidate for Dry AMD Treatment

In a new paper published in Aging, researchers have determined that directly improving autophagy through flubendazole (FLBZ) is potentially useful in treating dry age-related macular degeneration (AMD), a disease that causes vision loss. An accumulation of lipids Dry AMD shares a surprising commonality with atherosclerosis. As

Muscle fibers

NMN Human Trial Suggests Improved Muscle Glucose Metabolism

In recent years, there has been considerable interest in the naturally occurring molecule and dietary supplement nicotinamide mononucleotide (NMN) and its potential influence on aging. While there have been numerous animal studies suggesting that it may be useful in combating some age-related decline, there has been

Depression can potentially accelerate aging.

GrimAge Links Aging and Major Depression

People with major depressive disorder may have a biological age as much as two years greater than their chronological age, according to a new study [1]. The discovery provides a first step towards understanding the biological mechanisms that link depression to decreased lifespan. A link between

Spermidine supplement may slow down aging.

Spermidine for Cognitive Function in Flies, Mice, and Humans

Recently published research in Cell Reports provides a detailed account of dietary spermidine improving cognition and mitochondrial function in flies and mice, with some prospective human data to top it off. Spermidine and longevity Spermidine is known to decline with aging, and treatment with spermidine extends

Mouse brain maze

B-cell Depletion Ameliorates Alzheimer’s in Mice

According to a new study, Alzheimer’s disease is connected to inflammaging, which causes B-cells to change their phenotype and hamper amyloid-β (Aβ) removal [1]. Following successful experiments in vivo, the scientists propose B cell depletion as a possible therapy. The darker side of B cells    Alzheimer’s

Increased Longevity and Overpopulation

Any discussion of rejuvenation biotechnology almost certainly includes the subject of overpopulation and the objection that medical advances that directly address the various processes of aging will lead to an overpopulated world. Such dire predictions are a common theme in many discussions involving advances in medicine that could increase human