Lifespan Research Institute

Category: News

Rejuvenation Roundup March

Rejuvenation Roundup March 2021

It might be April Fool’s Day, but with the ongoing pandemic, age-related diseases are even less funny this year than they were last year. Let’s take a look at what

An image of colorectal cancer.

Stopping Colorectal Cancer From Proliferating

In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger

Dictator

Increased Longevity and Immortal Dictators

Suppose there was a country ruled by an evil dictator. Further, suppose the entire world was plagued by a terrible disease affecting 100% of the population. The disease isn’t infectious,

The thyroid gland

Thyroid Organoids Created From Human Tissue

In a new study published in Stem Cell Reports, researchers have developed organoids to replace thyroid function [1]. If this approach is fully fleshed out and successfully brought to the

A Summary of B Cells

The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by

Empty wallet

Broadening Longevity Research to Social Factors

The time has come for anti-aging research to incorporate behavioral and social science into its agenda, according to Terrie Moffitt, a psychology and neuroscience professor at Duke University [1]. She

Would Increased Longevity Be Boring?

Everlasting boredom is a common concern when it comes to the idea of extended human lifespans. There are many people who expect life to become empty and meaningless with time

The senate building.

The Senate Special Committee on Aging Needs Better Focus

The good news is that the United States Senate has a Special Committee on Aging. The bad news is that it has little to do with the actual processes of aging and has not meaningfully furthered the research necessary to develop medical treatments for aging itself.

VitaDAO

VitaDAO to Launch Longevity Biotech by Democracy

VitaDAO wants to democratize biotech VitaDAO will aim to fund longevity research, give its members ownership of the resulting IP, and allow members to vote on the direction of the organization. Few would argue that the drug development process is efficient. Even as the technology surrounding

Rejuvenation Roundup March

Rejuvenation Roundup March 2021

It might be April Fool’s Day, but with the ongoing pandemic, age-related diseases are even less funny this year than they were last year. Let’s take a look at what people have been doing about them in March. LEAF News Promising to connect biotech innovators and

NAD+ Eases Symptoms of a Premature Aging Disease in Mice

Scientists have alleviated symptoms of the rare premature aging disease ataxia-telangiectasia using NAD+ supplementation in a mouse model [1]. This success deepens our understanding of the role NAD+ plays in aging. The ubiquitous facilitator The coenzyme nicotinamide adenine dinucleotide (NAD+) is one of the foundations of

An image of colorectal cancer.

Stopping Colorectal Cancer From Proliferating

In a cell culture study, researchers have discovered that forcing cancer cells to differentiate into somatic cells can cause them to stop proliferating. Cancer, stem cells, and proliferation The danger of cancer is from its proliferation: its uncontrolled division within the body. This proliferation is explained

Dictator

Increased Longevity and Immortal Dictators

Suppose there was a country ruled by an evil dictator. Further, suppose the entire world was plagued by a terrible disease affecting 100% of the population. The disease isn’t infectious, but it is congenital. It progresses extremely slowly over the course of several decades, but it

NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of nucleic acid RNA.

What is NMN? A Summary of Nicotinamide Mononucleotide

What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. On the molecular level, it is a ribonucleotide, a basic structural unit of nucleic acid RNA. In form it consists of a nicotinamide group, a ribose and a phosphate

CGI of kidneys

Shortened Telomeres Increase Kidney Fibrosis Rates in Mice

A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The new study not only clearly demonstrates this link but also provides mouse models which can be

Exosomes

MSC Extracellular Vesicles Reduce Mouse Senescence

A new study in Aging Cell has shown extracellular vesicles from stem cells to extend healthspan and reduce cellular senescence in vitro and in mice. Stem cell exhaustion is a well-studied hallmark of aging that occurs in multiple model organisms and multiple tissue types in humans.

The thyroid gland

Thyroid Organoids Created From Human Tissue

In a new study published in Stem Cell Reports, researchers have developed organoids to replace thyroid function [1]. If this approach is fully fleshed out and successfully brought to the clinic, it may become a true cure for hypothyroidism. A common but harmful affliction Hypothyroidism is

Alzheimer's disease

Human Trial Suggests Clearing Plaques Slows Mental Decline

Until now, it was unclear as to whether drugs that clear amyloid, which accumulate in the brain during aging and accompany diseases such as Alzheimer’s, have any influence over cognitive decline. Previous studies have aimed to find this out, but results have been inconclusive due to

A Summary of B Cells

The immune system as a whole can be broadly separated into two main branches: the innate immune response and the adaptive immune response. The innate immune response is performed by a system that is always present across the body, while the adaptive immune response appears only

Cells signalling

Reduced Nicotinamide Mononucleotide Is a New NAD+ Precursor

There has been a lot of attention given to the NAD precursors nicotinamide mononucleotide (NMN) and nicotinamide riboside (NR), sold as dietary supplements, to restore nicotinamide adenine dinucleotide (NAD) levels. However, a new study suggests that there could be a new game in town with the

Empty wallet

Broadening Longevity Research to Social Factors

The time has come for anti-aging research to incorporate behavioral and social science into its agenda, according to Terrie Moffitt, a psychology and neuroscience professor at Duke University [1]. She explains that doing so will help researchers translate fundamental findings into useful therapies and guide us

Would Increased Longevity Be Boring?

Everlasting boredom is a common concern when it comes to the idea of extended human lifespans. There are many people who expect life to become empty and meaningless with time because everything has been already experienced; there is nothing else to discover, nothing else can surprise