Lifespan Research Institute

Category: News

Tweezers remove a single gene

Groundbreaking New Therapy for Progeria

A gene editing technique published in Nature has proven to be effective in a mouse model of Hutchinson–Gilford progeria syndrome (HGPS). A single error causes tremendous damage HGPS is a

double strand break

A Cause of Genomic Instability Discovered

Research further illuminating the mechanisms of impaired DNA damage repair associated with aging has recently been published in the journal Aging. DNA damage repair is reduced as we age  While

The pro-aging trance stops people seeing aging as a problem.

Emerging From the Pro-Aging Trance

Has the tide turned for rejuvenation biotechnology? It seems that opposition against medicine that seeks to slow, halt, or reverse aging may be slowly starting to crumble. For example, Lifespan.io’s

Rejuvenation Roundup image

Rejuvenation Roundup December 2020

Happy holidays from the Lifespan Extension Advocacy Foundation! While 2020 has been a trying year in many respects, rejuvenation research has continued throughout, and we are pleased to announce that

Annual report 2019 front cover

Holiday Wishes from Lifespan.io

As the holidays approach, I want to take this opportunity to sincerely thank you for being part of our community at Lifespan.io and helping to bring an end to the

Novos image

NOVOS Plans to Launch a Nutraceutical for Aging

Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes

Chromosomes and telomere loss

New Discovery in How Stem Cells Protect Telomeres

Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality

clockwork suit

New Aging Clock May Be Most Accurate to Date

These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using

Eye

Gene Therapy Trial Successfully Improves Vision

A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully

Tweezers remove a single gene

Groundbreaking New Therapy for Progeria

A gene editing technique published in Nature has proven to be effective in a mouse model of Hutchinson–Gilford progeria syndrome (HGPS). A single error causes tremendous damage HGPS is a well-known disease that causes visible aging and early death in children. In progeria, the lamina that

double strand break

A Cause of Genomic Instability Discovered

Research further illuminating the mechanisms of impaired DNA damage repair associated with aging has recently been published in the journal Aging. DNA damage repair is reduced as we age  While we have multiple mechanisms for repairing genomic damage, one type of damage, double-strand breaks, is particularly

Interview image for Tina Woods

Tina Woods: A Social Entrepreneur in the Longevity Field

Tina Woods is a UK-based founder of several social enterprises in healthcare and longevity and the author of the book Live Longer with AI, which we recently reviewed. In this interview, Tina shares valuable insights on how social entrepreneurship works in our field, what governments can

Strawberries

Fisetin May Be Useful in Treating Pulmonary Fibrosis

The results of a recent study suggest that fisetin appears to reduce the development of bleomycin-induced pulmonary fibrosis [1]. Fisetin is a plant polyphenol and part of the flavonoid group in the flavonol sub-category. The earliest record of isolated fisetin dates back to 1833 from the

The pro-aging trance stops people seeing aging as a problem.

Emerging From the Pro-Aging Trance

Has the tide turned for rejuvenation biotechnology? It seems that opposition against medicine that seeks to slow, halt, or reverse aging may be slowly starting to crumble. For example, Lifespan.io’s current crowdfunding campaign is going extremely well, and journalists begin to talk about senolytics in more

Rejuvenation Roundup image

Rejuvenation Roundup December 2020

Happy holidays from the Lifespan Extension Advocacy Foundation! While 2020 has been a trying year in many respects, rejuvenation research has continued throughout, and we are pleased to announce that we have plenty to discuss before we part for the holiday season. LEAF News We would

Mouse brain maze

Stem Cell Growth Factors Treat Alzheimer’s in Aged Mice

A new article published in Aging and Disease has taken a look at what two stem cell-activating growth factors can do in aged mice with Alzheimer’s-like pathology. Alzheimer’s disease (AD) is perhaps the most age-related of all age-related diseases. Perhaps not coincidentally, it has also been

Biohackers after blood transfer

Biohackers Perform First Plasma Dilution Experiment on Humans

We interviewed a group of Russian biohackers who performed a plasma dilution experiment on themselves. This experiment, the first of its kind, was based on previous mouse studies by Drs. Irina and Michael Conboy. Some molecules, while essential for various body functions, can be harmful when

Annual report 2019 front cover

Holiday Wishes from Lifespan.io

As the holidays approach, I want to take this opportunity to sincerely thank you for being part of our community at Lifespan.io and helping to bring an end to the diseases of aging. 2020 has been a difficult year, but through it all, you have helped

Novos image

NOVOS Plans to Launch a Nutraceutical for Aging

Today, we want to spotlight NOVOS, a nutraceutical company that is focused on developing science-based nutraceuticals to slow down aging and that will offer tests to track people’s aging processes and get a better picture of their health. The company is launching two new supplements: NOVOS

DNA double Helix being repaired

MYSM1 Prolongs Lifespan by Regulating DNA Repair

New research has shown that a DNA repair gene modulates lifespan in mice [1]. This may serve as a therapeutic avenue or at least open the way towards dissecting the links between DNA damage and senescence. MYSM1 is a gene that removes a molecular mark known

rat on a petri dish

Decellularized, Functional Thymus Regeneration in Mice

Recent research published in Nature Communications has regenerated a functional thymus in mice, making several other discoveries along the way [1]. A new sub-type of thymus cell emerges Although it is imperative to our immune health, the thymus is an under-studied organ that slowly disappears as

Chromosomes and telomere loss

New Discovery in How Stem Cells Protect Telomeres

Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality of cancer cells [1]. Keeping telomeres in the loop One function of telomeres is to prevent

clockwork suit

New Aging Clock May Be Most Accurate to Date

These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using deep learning, has recently been created by the Hong Kong-based company Deep Longevity. There are two

Eye

Gene Therapy Trial Successfully Improves Vision

A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully treated 37 participants suffering from Leber hereditary optic neuropathy (LHON). A landmark trial for mitochondrial gene