Category: News
New Discovery in How Stem Cells Protect Telomeres
December 15, 2020
Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality
New Aging Clock May Be Most Accurate to Date
December 14, 2020
These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using
Gene Therapy Trial Successfully Improves Vision
December 11, 2020
A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully
Aging Brain Function Partially Restored With Small Molecule
December 10, 2020
Researchers from the University of California, San Francisco have discovered that a small molecule partially restores the cognitive abilities of mice suffering from age-related memory decline [1]. A response to
Kidney Progenitor Cells Derived from Urine
December 9, 2020
Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells
Reviewing CD38, a Regulator of NAD+
December 8, 2020
We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this
AI Cracks the Protein Folding Problem
December 8, 2020
Alphabet’s subsidiary DeepMind has all but solved the problem of predicting a protein’s shape from its amino acid sequence. DeepMind’s program AlphaFold reached close to 90% average accuracy, which is
Study Links Glucosamine and Chondroitin to Reduced Mortality
December 7, 2020
Glucosamine and chondroitin are commonly bundled together as a dietary supplement, and a new study suggests that taking them may significantly reduce mortality. This builds on a previous epidemiological study
Reversing Cellular Age in Mice Restores Vision
December 4, 2020
Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can
A New Biomaterial for Thymic Cells
December 3, 2020
New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both
A Key Gene Links Diet and Longevity
December 3, 2020
A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted
Neurological Aging and the Lifespan Limit
December 2, 2020
Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in
CRISPR Successfully Deployed Against Two Cancer Types
December 2, 2020
Scientists have successfully tested a new nanoparticle-based delivery system for CRISPR kits, achieving drastic improvements in mouse models of glioblastoma and ovarian cancer [1]. A gift from our single-cell ancestors
Rejuvenation Roundup November 2020
December 1, 2020
Thanksgiving is over, but we’re still thankful that so many people have decided to help stop the ravages of age-related disease by researching the causes of aging and joining the
Resveratrol Human Trial Results Published
November 30, 2020
A human study on the popular supplement resveratrol on heart failure patients has been published, and the results are significant. What is resveratrol? Resveratrol, is a naturally occurring stilbenoid, a
New Discovery in How Stem Cells Protect Telomeres
December 15, 2020
Scientists have discovered a new telomere-protecting mechanism in embryonic stem cells. This discovery can bring us closer to solving the notorious problem of telomere attrition and to understanding the immortality of cancer cells [1]. Keeping telomeres in the loop One function of telomeres is to prevent
New Aging Clock May Be Most Accurate to Date
December 14, 2020
These days, it seems like you cannot go for a walk without tripping over another aging clock, and today is no exception. DeepMAge, a DNA methylation aging clock developed using deep learning, has recently been created by the Hong Kong-based company Deep Longevity. There are two
Gene Therapy Trial Successfully Improves Vision
December 11, 2020
A team of researchers, including Dr. Patrick Yu-Wai-Man from the University of Cambridge and Dr. José-Alain Sahel from the University of Pittsburgh and Institut de la Vision, Paris, has successfully treated 37 participants suffering from Leber hereditary optic neuropathy (LHON). A landmark trial for mitochondrial gene
Aging Brain Function Partially Restored With Small Molecule
December 10, 2020
Researchers from the University of California, San Francisco have discovered that a small molecule partially restores the cognitive abilities of mice suffering from age-related memory decline [1]. A response to damage As the researchers explain, when neurons detect that something has gone wrong, either through the
Kidney Progenitor Cells Derived from Urine
December 9, 2020
Recent data published in Scientific Reports has characterized human urine-derived renal stem cells, a potential non-invasive source for kidney tissue engineering and regenerative medicine. An unlikely source for kidney cells The kidney is, by far, the most frequently transplanted organ. This is because donors are much
Reviewing CD38, a Regulator of NAD+
December 8, 2020
We recently explored why NAD+ declines during aging, and today, we want to spotlight a new review that takes a deep dive into CD38, one of the reasons for this decline [1]. The review focuses on one of the primary culprits of NAD+ decline, the enzyme
AI Cracks the Protein Folding Problem
December 8, 2020
Alphabet’s subsidiary DeepMind has all but solved the problem of predicting a protein’s shape from its amino acid sequence. DeepMind’s program AlphaFold reached close to 90% average accuracy, which is comparable to experimental structural analysis. Proteins: life’s multitool Proteins are the primary tool with which organisms
Study Links Glucosamine and Chondroitin to Reduced Mortality
December 7, 2020
Glucosamine and chondroitin are commonly bundled together as a dietary supplement, and a new study suggests that taking them may significantly reduce mortality. This builds on a previous epidemiological study from earlier this year, which showed that glucosamine supplementation correlates with reduced all-cause mortality. What are
Reversing Cellular Age in Mice Restores Vision
December 4, 2020
Researchers at the Sinclair Lab at Harvard Medical School have restored lost vision to old mice, and mice with damaged retinal nerves, using partial cellular reprogramming. The aged cells can be reset to become younger again using this approach and are better at repairing damaged tissue.
A New Biomaterial for Thymic Cells
December 3, 2020
New research published in Biomacromolecules has successfully cultured thymic epithelial cells in vitro. A 3D biomaterial for thymic epithelial cells Tissue engineering and regenerative medicine attempts to regenerate tissues both in the lab and in vivo. While the fact that everyone experiences thymic involution should make
A Key Gene Links Diet and Longevity
December 3, 2020
A key gene mediating the effect of dietary restriction on longevity has been identified, improving our understanding of the link between the two and raising the prospect of more targeted therapeutic interventions. Less is more Dietary restriction is one of the most reliable ways to increase
Neurological Aging and the Lifespan Limit
December 2, 2020
Jeanne Louise Calment from France was the oldest person to grace this Earth, living a full life until 122 years of age [1]. She continuously exercised, taking up fencing in her 80s and cycling in her 100s. She claimed to have achieved such a long life
CRISPR Successfully Deployed Against Two Cancer Types
December 2, 2020
Scientists have successfully tested a new nanoparticle-based delivery system for CRISPR kits, achieving drastic improvements in mouse models of glioblastoma and ovarian cancer [1]. A gift from our single-cell ancestors CRISPR gene editing technology has been widely hailed as a potential game changer in medicine, including
Rejuvenation Roundup November 2020
December 1, 2020
Thanksgiving is over, but we’re still thankful that so many people have decided to help stop the ravages of age-related disease by researching the causes of aging and joining the organizations needed to bring this research to people, and we’re definitely thankful for everyone who chooses
Resveratrol Human Trial Results Published
November 30, 2020
A human study on the popular supplement resveratrol on heart failure patients has been published, and the results are significant. What is resveratrol? Resveratrol, is a naturally occurring stilbenoid, a type of phenol that is present in various plants and foods, such as grapes, peanuts, cocoa,