Category: News
New iPhone App Measures Biological Age
September 18, 2020
A new app created by Hong Kong-based Deep Longevity might help you stay in your prime longer, keep your mind sharp, and maintain habits that keep your biological age lower
Senolytic Reverses Chemotherapy-Induced Neuropathy in Mice
September 17, 2020
Researchers have discovered that removing senescent-like neurons alleviates peripheral neuropathy caused by cisplatin, a powerful chemotherapy drug, in mice. Cisplatin As the researchers of this study explain, cisplatin is a
BMP4 and VEGF Promote Bone Regeneration
September 16, 2020
Because of bone’s natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
Delivering MicroRNA to Cells Ameliorates Inflammaging
September 15, 2020
A group of researchers has found that extracellular vesicles carrying a specific type of microRNA can attenuate age-related inflammation and increase immune response following flu vaccination in mice [1]. Extracellular
Why NAD+ Declines During Aging – Part 2
September 14, 2020
This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the previous part, you can find it here. Today, we are
Methylation Clocks that Measure the Biological Age of Cats
September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that
Caloric Restriction Improves DNA Repair in Mice
September 10, 2020
A short-term caloric restriction diet enhanced a DNA repair process known as non-homologous end joining. These results may partially explain how caloric restriction and similar diets increase lifespan and healthspan
Tissue Engineering and Regenerative Medicine in Longevity
September 9, 2020
This is part one of a new weekly series focusing on recent advancements in the field of regenerative medicine. The field of tissue engineering and regenerative medicine Tissue engineering and
Brown Fat Transplantation Reduces Obesity in Mice
September 8, 2020
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity:
Alpha-Ketoglutarate Extends Healthspan in Aging Mice
September 3, 2020
A research team led by Dr. Brian Kennedy has shown that administration of alpha-ketoglutarate (AKG) improves both lifespan and healthspan in middle-aged mice. Modest increase in lifespan from Alpha-Ketoglutarate For
Microglial Cells Successfully Replaced by Transplantation
September 1, 2020
A group of researchers has proposed three robust transplantation techniques for fighting microglia-related conditions, such as Alzheimer’s, and potentially boosting our cognitive abilities [1]. The sentinels of the brain Microglial
Rejuvenation Roundup August 2020
September 1, 2020
Ending Age-Related Diseases 2020 has concluded! Our first online conference, with two full days of talks from professionals from both the research and investment fields, has finished. We will be
Gene Therapy Improves Motor Function in Aged Mice
August 27, 2020
A gene therapy treatment can ameliorate the loss of motor function and muscle strength in old mice, offering elderly people hope for continuing their active lives. DOK7 is crucial for
My Experience Attending Ending Age-Related Diseases 2020
August 26, 2020
Last week, on Thursday and Friday, I attended a conference. No, it wasn’t in a bustling hot conference center, with thousands of other people much closer than 6 feet from
Stem Cells Produce Healthy Cartilage in Osteoarthritic Joints
August 25, 2020
A collective of scientists has shown that osteoarthritis can be alleviated by guiding skeletal stem cells towards differentiation into chondrocytes, which are responsible for producing healthy cartilage [1]. Osteoarthritis (OA)
New iPhone App Measures Biological Age
September 18, 2020
A new app created by Hong Kong-based Deep Longevity might help you stay in your prime longer, keep your mind sharp, and maintain habits that keep your biological age lower than your chronological age. Introducing Young.ai It has been an increasing trend in recent years for
Senolytic Reverses Chemotherapy-Induced Neuropathy in Mice
September 17, 2020
Researchers have discovered that removing senescent-like neurons alleviates peripheral neuropathy caused by cisplatin, a powerful chemotherapy drug, in mice. Cisplatin As the researchers of this study explain, cisplatin is a chemotherapy drug that works by causing platination in nuclear DNA, which leads to cellular failure, senescence,
BMP4 and VEGF Promote Bone Regeneration
September 16, 2020
Because of bone’s natural self-healing abilities, it has provided regenerative medicine with some of its earliest successes. However, as with many tissues, the defects that can be treated are currently limited in size.
Delivering MicroRNA to Cells Ameliorates Inflammaging
September 15, 2020
A group of researchers has found that extracellular vesicles carrying a specific type of microRNA can attenuate age-related inflammation and increase immune response following flu vaccination in mice [1]. Extracellular vesicles (EVs) are an important part of intercellular communication. These tiny nanoscale bubbles are secreted by
Why NAD+ Declines During Aging – Part 2
September 14, 2020
This is part 2 of a series focused on the age-related decline of NAD+; if you have not read the previous part, you can find it here. Today, we are continuing our look at some of the evidence for the age-related decline of NAD+ in humans
Methylation Clocks that Measure the Biological Age of Cats
September 11, 2020
Today, we have something a little bit different: progress in aging biomarkers but, this time, for cats! The race has been on for some years now to create biomarkers that can accurately measure biological age. Having such biomarkers is critical in the development of therapies that
Caloric Restriction Improves DNA Repair in Mice
September 10, 2020
A short-term caloric restriction diet enhanced a DNA repair process known as non-homologous end joining. These results may partially explain how caloric restriction and similar diets increase lifespan and healthspan in a wide range of organisms. Eat less, live longer Caloric restriction – that is, reduced
Tissue Engineering and Regenerative Medicine in Longevity
September 9, 2020
This is part one of a new weekly series focusing on recent advancements in the field of regenerative medicine. The field of tissue engineering and regenerative medicine Tissue engineering and regenerative medicine (TERM) is a large and rapidly growing field that has implications for the field
Brown Fat Transplantation Reduces Obesity in Mice
September 8, 2020
A group of researchers has used CRISPR to create energy-dissipating brown adipocytes (fat cells) from white preadipocytes. The new cells were then shown to alleviate obesity in mice [1]. Obesity: the nemesis of longevity Obesity is one of humanity’s deadliest enemies. It is a known comorbidity
Alpha-Ketoglutarate Extends Healthspan in Aging Mice
September 3, 2020
A research team led by Dr. Brian Kennedy has shown that administration of alpha-ketoglutarate (AKG) improves both lifespan and healthspan in middle-aged mice. Modest increase in lifespan from Alpha-Ketoglutarate For this study, the researchers administered a calcium salt of AKG, CaAKG, to 18-month-old male and female
Microglial Cells Successfully Replaced by Transplantation
September 1, 2020
A group of researchers has proposed three robust transplantation techniques for fighting microglia-related conditions, such as Alzheimer’s, and potentially boosting our cognitive abilities [1]. The sentinels of the brain Microglial cells form the backbone of our brain’s immune system. They perform a wide variety of functions,
Rejuvenation Roundup August 2020
September 1, 2020
Ending Age-Related Diseases 2020 has concluded! Our first online conference, with two full days of talks from professionals from both the research and investment fields, has finished. We will be providing videos from that conference in the coming months, but three have already been made available.
Gene Therapy Improves Motor Function in Aged Mice
August 27, 2020
A gene therapy treatment can ameliorate the loss of motor function and muscle strength in old mice, offering elderly people hope for continuing their active lives. DOK7 is crucial for muscle function Declining motor function is common with aging and can significantly reduce the quality of
My Experience Attending Ending Age-Related Diseases 2020
August 26, 2020
Last week, on Thursday and Friday, I attended a conference. No, it wasn’t in a bustling hot conference center, with thousands of other people much closer than 6 feet from me talking about tech and disrupting various industries. Instead, I was sitting at home with my
Stem Cells Produce Healthy Cartilage in Osteoarthritic Joints
August 25, 2020
A collective of scientists has shown that osteoarthritis can be alleviated by guiding skeletal stem cells towards differentiation into chondrocytes, which are responsible for producing healthy cartilage [1]. Osteoarthritis (OA) is a classic example of an age-related disease. While almost non-existent in younger people, it affects