Lifespan Research Institute

Category: News

Buckyball

C60 Does Not Improve Lifespan nor Healthspan

Buckminsterfullerene, also known as C60, is a remarkable molecule with a range of interesting chemical and physical properties. Several years ago, C60 came to the attention of the longevity community

Heart scaffold

The Extracellular Matrix Is Key to Heart Health

A new article published by the International Journal of Molecular Sciences sheds light on the differences between the extracellular matrix (ECM) of healthy people and people in end-stage heart failure.

Rejuvenation Roundup October

Rejuvenation Roundup October 2020

Spooky season has come and gone, but the Grim Reaper is still chasing us down. Fortunately, we’ve learned quite a bit over the last month in finding ways to stop

Cartilage cells

Cartilage Regeneration Accomplished in Vitro

New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. The challenges of cartilage regeneration Regenerative medicine strategies aim to regenerate the

Finding the Fountain book

Breanna Deutsch Explains How to Find the Fountain

Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide

DNA data

A Genetic Footprint of Aging

A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study

Gene segment

Using CRISPR to Remove Mutated DNA to Defeat Cancer

Researchers have successfully used the CRISPR/Cas9 gene editing tool to destroy Ewing’s sarcoma and chronic myeloid leukemia tumor cells by targeting the fusion genes responsible for these tumors [1]. Fusion

EGCG chemical

Uncovering the Origin of the SASP

A new study published in Nature shows a strong link between the protein G3BP1 and the SASP, a harmful byproduct of senescent cells.

Fat cells

Fatty Tissue Generated on a Chip

Recent research published in the scientific journal Lab on a Chip sheds light on the behavior of adipocytes, the primary cells of our fat tissue.

Buckyball

C60 Does Not Improve Lifespan nor Healthspan

Buckminsterfullerene, also known as C60, is a remarkable molecule with a range of interesting chemical and physical properties. Several years ago, C60 came to the attention of the longevity community several years ago when a study with a small cohort of rats found that C60 dissolved

Heart scaffold

The Extracellular Matrix Is Key to Heart Health

A new article published by the International Journal of Molecular Sciences sheds light on the differences between the extracellular matrix (ECM) of healthy people and people in end-stage heart failure. The key to the heart could be its ECM Regeneration of heart tissue following a heart

Breanna Deutsch interview

Breanna Deutsch Wants You to Contact Lawmakers About Aging

Today, we are interviewing Breanna Deutsch, a policy expert and the author of Finding the Fountain, which we have previously reviewed. Breanna comes from the world of political communications, and she explains what needs to be done to encourage policymakers to pave the way for a

Rejuvenation Roundup October

Rejuvenation Roundup October 2020

Spooky season has come and gone, but the Grim Reaper is still chasing us down. Fortunately, we’ve learned quite a bit over the last month in finding ways to stop Death from getting a hold of us quite so soon. LEAF News Based in the United

Elderly resistance training

Metformin and Resistance Training: Downside and Upside

A new study published in Aging has shown that although taking metformin while undergoing resistance training limits muscle growth, it promotes youthful gene expression. The downside As the researchers of this study point out, previous research shows that taking metformin while undergoing physical resistance training (PRT)

Cartilage cells

Cartilage Regeneration Accomplished in Vitro

New research published in Stem Cell Research and Therapy has improved the regenerative potential of chondrocytes in vitro. The challenges of cartilage regeneration Regenerative medicine strategies aim to regenerate the natural cartilage itself to its former glory. This can be either by kick-starting the body’s own

Finding the Fountain book

Breanna Deutsch Explains How to Find the Fountain

Aging research is still an emerging field, and its emergence has been laden with difficulties. Until recently, the budgets were scarce, the ideas ridiculed, and public involvement nonexistent. The tide is turning, with more private and institutional players eager to spend money and effort on the

Partial Cellular Reprogramming Improves Memory in Old Mice

Today, we want to highlight another study that takes us a step closer to getting partial cellular reprogramming to the clinic. Can we both have our cake and eat it? As previous studies [1] have taught us, partial cellular reprogramming is a balancing act of epigenetically

DNA data

A Genetic Footprint of Aging

A new analysis has revealed a core set of genes involved in aging in both humans and mice. Together with a broader set of age-related genes assembled by the study [1], this resource will serve as a launching point for further investigations of the mechanisms behind

Telomeres

A New Mechanism of Telomere Lengthening in T Cells Discovered

An international collective of scientists has discovered a new cellular process: telomere transfer from antigen-presenting cells to T cells that boosts the latter’s lifespan and proliferative potential [1]. T cells, an important element of our adaptive immune system, are born as non-proliferating cells and, as such,

Gene segment

Using CRISPR to Remove Mutated DNA to Defeat Cancer

Researchers have successfully used the CRISPR/Cas9 gene editing tool to destroy Ewing’s sarcoma and chronic myeloid leukemia tumor cells by targeting the fusion genes responsible for these tumors [1]. Fusion genes, a feature in many different types of cancer, arise when a mutation fuses two genes

Taisho Pharmaceutical logo

Insilico Partners with Taisho for Senolytic Drug Discovery

Insilico Medicine has announced a historic deal with the Taisho Pharmaceutical Company, which is based in Japan, in a partnership to identify and develop new senolytic drugs. The companies have agreed to collaborate on AI-powered drug discovery focused on identifying molecules to remove problematic senescent cells.

EGCG chemical

Uncovering the Origin of the SASP

A new study published in Nature shows a strong link between the protein G3BP1 and the SASP, a harmful byproduct of senescent cells.

Fat cells

Fatty Tissue Generated on a Chip

Recent research published in the scientific journal Lab on a Chip sheds light on the behavior of adipocytes, the primary cells of our fat tissue.