Category: News
Frailty and Age-Related Immune Decline Reversed in Mice
July 8, 2020
Frailty and the decline of the immune system are two typical features of aging, but new research shows that both can be halted and even somewhat reversed using a novel
Repetitions in Our DNA React to Anti-Aging Interventions
July 7, 2020
A group of scientists from Colorado State University has discovered that repetitive elements (REs) in our DNA increase with aging and react to known longevity-promoting interventions [1]. Are REs genomic
Edwina Rogers – Effective Advocacy for Longevity
July 6, 2020
We had the opportunity to interview Edwina Rogers, CEO of the Global Healthspan Policy Institute and a professional public health advocate supporting aging research. Edwina has degrees in corporate finance
Parkinson’s Disease Symptoms Reversed in Mice
July 3, 2020
Researchers have found that blocking the activity of a single gene causes other cell types to become dopamine-producing neurons, a type of neuron that Parkinson’s disease destroys. What is Parkinson’s
Two Proteins Allow LDL Cholesterol into Our Cells
July 2, 2020
Researchers have found out how LDL cholesterol is able to enter our cells with the help of two proteins that form a doorway into the cell. The findings have ramifications
Rejuvenation Roundup June 2020
July 1, 2020
This has been a productive month for rejuvenation biotechnology companies, longevity researchers, and us here at Lifespan.io. Let’s take a look at what’s happened in June. LEAF News Why I
Pilot Study Results Suggest Epigenetic Age Reversal
June 30, 2020
Today, we want to highlight a press release from Ponce de Leon Health that talks about the results of a pilot consumer trial that the company has recently concluded. The
New Evidence of Common Genetic Causes in Age-Related Diseases
June 30, 2020
By using a large UK health databank and advanced methods of statistical analysis, scientists have discovered genetic ties between various age-related diseases and proposed several candidate drugs for upstream intervention.
A Biomarker Based on Senescent Cell Secretions
June 29, 2020
Researchers have published a new study suggesting that some of the inflammatory signals secreted by senescent cells could be used as a biomarker to measure aging and health. What are
Nanoparticles Deliver Twin Drug Payload for Atherosclerosis
June 26, 2020
Cyclodextrins have been of particular interest in the context of treating atherosclerosis, so today we want to highlight some interesting research that uses a novel delivery method to combat this
Reversing Atherosclerosis by Resetting Gut Bacteria
June 25, 2020
A new study has seen researchers alter the balance of harmful bacteria in the gut microbiome to reduce cholesterol and reverse atherosclerosis in mice fed a high-fat Western diet. What
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently
Frailty and Age-Related Immune Decline Reversed in Mice
July 8, 2020
Frailty and the decline of the immune system are two typical features of aging, but new research shows that both can be halted and even somewhat reversed using a novel cell-based therapy. Frailty and immunosenescence Frailty is something that frequently affects older people, and it ultimately
Repetitions in Our DNA React to Anti-Aging Interventions
July 7, 2020
A group of scientists from Colorado State University has discovered that repetitive elements (REs) in our DNA increase with aging and react to known longevity-promoting interventions [1]. Are REs genomic parasites? At the dawn of genomic research scientists were stunned to learn that as much as
Edwina Rogers – Effective Advocacy for Longevity
July 6, 2020
We had the opportunity to interview Edwina Rogers, CEO of the Global Healthspan Policy Institute and a professional public health advocate supporting aging research. Edwina has degrees in corporate finance and law. She worked for four U.S. Presidents and two U.S. Senators, helping to shape national
Parkinson’s Disease Symptoms Reversed in Mice
July 3, 2020
Researchers have found that blocking the activity of a single gene causes other cell types to become dopamine-producing neurons, a type of neuron that Parkinson’s disease destroys. What is Parkinson’s disease? Parkinson’s disease is a progressive, age-related, neurodegenerative disease that mainly affects the motor system and
Two Proteins Allow LDL Cholesterol into Our Cells
July 2, 2020
Researchers have found out how LDL cholesterol is able to enter our cells with the help of two proteins that form a doorway into the cell. The findings have ramifications for treating heart disease, which is currently the world’s greatest killer. Revealing how LDL gets into
Rejuvenation Roundup June 2020
July 1, 2020
This has been a productive month for rejuvenation biotechnology companies, longevity researchers, and us here at Lifespan.io. Let’s take a look at what’s happened in June. LEAF News Why I Am Still Future Positive on My Birthday: Board member Steve Hill shares his musings on his
Pilot Study Results Suggest Epigenetic Age Reversal
June 30, 2020
Today, we want to highlight a press release from Ponce de Leon Health that talks about the results of a pilot consumer trial that the company has recently concluded. The company claims that it has been successful in reducing the epigenetic age of participants by an
New Evidence of Common Genetic Causes in Age-Related Diseases
June 30, 2020
By using a large UK health databank and advanced methods of statistical analysis, scientists have discovered genetic ties between various age-related diseases and proposed several candidate drugs for upstream intervention. Building age-of-onset profiles of diseases The very fact that multitudes of age-related diseases (ARDs) exist alludes
A Biomarker Based on Senescent Cell Secretions
June 29, 2020
Researchers have published a new study suggesting that some of the inflammatory signals secreted by senescent cells could be used as a biomarker to measure aging and health. What are senescent cells? As you age, increasing numbers of your cells enter into a state known as
Nanoparticles Deliver Twin Drug Payload for Atherosclerosis
June 26, 2020
Cyclodextrins have been of particular interest in the context of treating atherosclerosis, so today we want to highlight some interesting research that uses a novel delivery method to combat this disease. Nanoparticles improve drug delivery Cyclodextrins describe a group of cyclic oligosaccharides, which have a varied
Reversing Atherosclerosis by Resetting Gut Bacteria
June 25, 2020
A new study has seen researchers alter the balance of harmful bacteria in the gut microbiome to reduce cholesterol and reverse atherosclerosis in mice fed a high-fat Western diet. What is the gut microbiome? The gut microbiome describes the varied community of bacteria, archaea, eukarya, and
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual in the brain. As the researchers explain, the normal method for determining whether or not a
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age,
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in many age-related conditions. What are senescent cells? As you age, increasing numbers of your cells enter
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently affecting around 390 children. Their average life expectancy is around 13 years, but some affected individuals