Category: News
A Vaccine for Senescent Cells
May 29, 2020
Could a vaccine approach to removing harmful senescent cells that accumulate with age be an alternative to senolytic drugs, which destroy them? Some researchers certainly believe it might and have
The CellAge Database Charts Cellular Senescence
May 28, 2020
The Human Ageing Genomic Resources (HAGR) is a collection of curated databases and tools designed to help researchers study the genetics of human aging through modern approaches such as functional
A New Method for Detecting Mitophagy
May 28, 2020
Researchers from the Laboratory for Cell Function Dynamics in Japan have developed a new method for detecting mitophagy, the process of recycling damaged mitochondria. The Necessity of Mitophagy Our mitochondria
Lifespan.io Appears on the Damage Report
May 27, 2020
As part of our mission to engage the wider public audience, Lifespan.io President Keith Comito has recently appeared on the Damage Report, a politics and current events show hosted by
The Plasma Proteome Reveals a New Target for Osteoporosis
May 26, 2020
Recently, a group of South Korean scientists has analyzed the blood proteome of mice to determine how it changes with age and to identify aging-related proteins that have previously eluded
NAD+ and the Circadian Rhythm
May 25, 2020
A new study may shed some light on how aging and circadian rhythms may be linked by discovering a role for nicotinamide adenine dinucleotide (NAD+) in preventing the age-related disruption
SYK Inhibitors May Be a New Class of Senolytics
May 22, 2020
At this moment in history, the study of the biology of aging frequently brings us new discoveries, and today is no exception. Researchers have discovered a new drug that appears
New Possible Treatment for Osteoarthritis Reported
May 19, 2020
Researchers have successfully reversed the course of osteoarthritis in rats by combining two molecules, one of which, a-Klotho, has long been a popular subject of anti-aging research. A classic age-related
Jim Mellon Donates £1 Million to Aging Research
May 18, 2020
Investment mogul Jim Mellon has donated a record-breaking 1 million British pounds to Oriel College in the United Kingdom, offering a ray of light for aging research. Supporting fundamental research
Metformin Enhances Autophagy and Alleviates Inflammaging
May 14, 2020
A recent study published in Cell Metabolism has shown that metformin, a drug that has been previously shown to be effective against some aspects of aging, ameliorates inflammaging by promoting
Resistance Training in Middle Age Doubles Muscle NAD+ Levels
May 13, 2020
A new study suggests that we can actively fight back against age-related decline with resistance training to restore our levels of NAD+, a critical molecule used by the mitochondria in
A Senolytic Prodrug For Multiple Cell Types
May 12, 2020
A group of scientists from China has successfully created an effective senolytic prodrug that targets the enzyme β-galactosidase [1]. This prodrug, called SSK1, has demonstrated impressive results across various cell
Blood Factors Reverse Epigenetic Age by Half in Rats
May 11, 2020
Researchers have demonstrated that epigenetic age can be halved in rats by using signals commonly found in the blood. Epigenetic changes One of the proposed reasons we age are the
The Challenge of Including Aging in the ICD
May 8, 2020
Few things in aging research are ever straightforward, and today’s topic is no exception, as two researchers enjoy some back and forth regarding whether and how the World Health Organization
The Moonshot Venture Fellowship
May 6, 2020
We had the opportunity to speak to Apollo Health Ventures about the Moonshot Venture Fellowship and about the aging research field in general from the perspective of a venture capital
A Vaccine for Senescent Cells
May 29, 2020
Could a vaccine approach to removing harmful senescent cells that accumulate with age be an alternative to senolytic drugs, which destroy them? Some researchers certainly believe it might and have published a new mouse study showing just that. What are senescent cells? As you age, increasing
The CellAge Database Charts Cellular Senescence
May 28, 2020
The Human Ageing Genomic Resources (HAGR) is a collection of curated databases and tools designed to help researchers study the genetics of human aging through modern approaches such as functional genomics, network analyses, systems biology and evolutionary analyses. One of the many databases in the HAGR
A New Method for Detecting Mitophagy
May 28, 2020
Researchers from the Laboratory for Cell Function Dynamics in Japan have developed a new method for detecting mitophagy, the process of recycling damaged mitochondria. The Necessity of Mitophagy Our mitochondria are the powerhouses of our cells, turning the food we eat into ATP, the form of
Lifespan.io Appears on the Damage Report
May 27, 2020
As part of our mission to engage the wider public audience, Lifespan.io President Keith Comito has recently appeared on the Damage Report, a politics and current events show hosted by John Iadarola, political host for the online news network The Young Turks. Regardless of anyone’s political
The Plasma Proteome Reveals a New Target for Osteoporosis
May 26, 2020
Recently, a group of South Korean scientists has analyzed the blood proteome of mice to determine how it changes with age and to identify aging-related proteins that have previously eluded researchers. After identifying several such proteins, the group focused on a specific protein, cadherin-13, that seems
NAD+ and the Circadian Rhythm
May 25, 2020
A new study may shed some light on how aging and circadian rhythms may be linked by discovering a role for nicotinamide adenine dinucleotide (NAD+) in preventing the age-related disruption of circadian rhythms in mice. A circadian rhythm is an automatic process that regulates a cycle
SYK Inhibitors May Be a New Class of Senolytics
May 22, 2020
At this moment in history, the study of the biology of aging frequently brings us new discoveries, and today is no exception. Researchers have discovered a new drug that appears to destroy lingering senescent cells, and it achieves this without using any of the previously known
New Possible Treatment for Osteoarthritis Reported
May 19, 2020
Researchers have successfully reversed the course of osteoarthritis in rats by combining two molecules, one of which, a-Klotho, has long been a popular subject of anti-aging research. A classic age-related disease Osteoarthritis (OA) is a classic example of a wear-and-tear disease. Its manifestations are in the
Jim Mellon Donates £1 Million to Aging Research
May 18, 2020
Investment mogul Jim Mellon has donated a record-breaking 1 million British pounds to Oriel College in the United Kingdom, offering a ray of light for aging research. Supporting fundamental research on aging In recent years, one of the real dynamos of our community has been British
Metformin Enhances Autophagy and Alleviates Inflammaging
May 14, 2020
A recent study published in Cell Metabolism has shown that metformin, a drug that has been previously shown to be effective against some aspects of aging, ameliorates inflammaging by promoting autophagy, the cellular recycling of damaged components. Mitochondrial dysfunction, autophagy, and TH17 Mitochondrial dysfunction is one
Resistance Training in Middle Age Doubles Muscle NAD+ Levels
May 13, 2020
A new study suggests that we can actively fight back against age-related decline with resistance training to restore our levels of NAD+, a critical molecule used by the mitochondria in our cells to produce energy. NAD+ and mitochondria The mitochondria are the powerhouses of the cell,
A Senolytic Prodrug For Multiple Cell Types
May 12, 2020
A group of scientists from China has successfully created an effective senolytic prodrug that targets the enzyme β-galactosidase [1]. This prodrug, called SSK1, has demonstrated impressive results across various cell types and advantages over some existing senolytics. Cellular senescence is a phenomenon in which cells stop
Blood Factors Reverse Epigenetic Age by Half in Rats
May 11, 2020
Researchers have demonstrated that epigenetic age can be halved in rats by using signals commonly found in the blood. Epigenetic changes One of the proposed reasons we age are the changes to gene expression that our cells experience as we get older; these are commonly called
The Challenge of Including Aging in the ICD
May 8, 2020
Few things in aging research are ever straightforward, and today’s topic is no exception, as two researchers enjoy some back and forth regarding whether and how the World Health Organization (WHO) should recognize the aging processes as a disease. Proposing a new framework to facilitate development
The Moonshot Venture Fellowship
May 6, 2020
We had the opportunity to speak to Apollo Health Ventures about the Moonshot Venture Fellowship and about the aging research field in general from the perspective of a venture capital firm. Apollo Health Ventures is a life science venture capital firm and life science company builder