Category: News
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently
Gut Bacteria Can Predict Your Biological Age
June 19, 2020
Can we use the bacteria in our gut to measure how biologically old we are? Some researchers certainly think we can and have developed a microbiome clock that examines the
Can Aging Research Prevent the Next Pandemic?
June 18, 2020
The world is reeling from the SARS-CoV-2 (COVID-19) pandemic, which has both had severe economic and humanitarian effects. As we continue to practice social distancing, we should ask ourselves: How
Hair Graying May Be Reversible
June 17, 2020
A team of researchers have discovered a novel way to study the process of hair graying, finding it potentially reversible and linked to psychological stress. The abundant anecdotal evidence of
Diluting Blood Plasma Rejuvenates Old Mice
June 16, 2020
Back in 2005, Drs. Irina and Michael Conboy showed that joining the circulatory systems of young and old mice together in a procedure called parabiosis could rejuvenate aged tissues and
Removing Some Senescent Cells May Have Consequences
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What
NAD+ Restores Mitochondrial Function in Egg Cells
June 11, 2020
Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it
Niacin May Prove Useful Against Brain Cancer
June 10, 2020
A possible new role for niacin has been discovered in the fight against brain cancer. An old vitamin Niacin is a form of vitamin B3 and has been a popular
A New Likely Mechanism Behind Osteoporosis Discovered
June 9, 2020
A group of Japanese scientists has found that advanced glycation end products (AGEs) tend to accumulate in osteoblasts with age, inducing apoptosis via endoplasmic reticulum stress. This mechanism likely contributes
Niacin Increases NAD+ Significantly in Human Trial
June 8, 2020
Researchers have concluded a human trial using niacin, a very old vitamin discovered over 80 years ago, and have shown that it can increase the presence of an energy compound
Why I Am Still Future Positive on My Birthday
June 5, 2020
Don’t let your birthday get you down and remind you that you are getting older; there are plenty of reasons to be cheerful about the future and your place in
Update from CellAge
June 4, 2020
Today is one of those days when we must deliver some bad news. Science is hard, particularly when it concerns the biology of aging, and things do not always go
A Strong Link Between Alzheimer’s and Senescence
June 24, 2020
In a recent study, researchers from the Buck Institute have shown that cellular senescence, one of the hallmarks of aging, is partially responsible for Alzheimer’s disease. Cellular senescence is unusual in the brain. As the researchers explain, the normal method for determining whether or not a
Role of the Immune System in Removing Senescent Cells
June 23, 2020
Could the immune system itself be the best way to purge senescent cells, which accumulate as we age, from the body? A new review takes a look at the role of the immune system in removing these problematic cells. What are senescent cells? As you age,
Deploying Immunotherapy Against Senescent Cells
June 22, 2020
Researchers are starting to test the use of immunotherapies, normally used for treating cancer, to target senescent cells, which accumulate in our bodies as we age and are implicated in many age-related conditions. What are senescent cells? As you age, increasing numbers of your cells enter
The Gene LMNA’s Effect on Aging
June 19, 2020
LMNA, a gene coding for lamins, whose mutations cause many developmental diseases, is linked to Hutchinson-Gilford Progeria (HGP) [1]. HGP is a disease that causes premature aging and is currently affecting around 390 children. Their average life expectancy is around 13 years, but some affected individuals
Gut Bacteria Can Predict Your Biological Age
June 19, 2020
Can we use the bacteria in our gut to measure how biologically old we are? Some researchers certainly think we can and have developed a microbiome clock that examines the bacteria living in our guts to predict our age. The microbiome The gut microbiome is a
Can Aging Research Prevent the Next Pandemic?
June 18, 2020
The world is reeling from the SARS-CoV-2 (COVID-19) pandemic, which has both had severe economic and humanitarian effects. As we continue to practice social distancing, we should ask ourselves: How can we avoid similar pandemics in the future? Aging and infectious disease are linked As we
Hair Graying May Be Reversible
June 17, 2020
A team of researchers have discovered a novel way to study the process of hair graying, finding it potentially reversible and linked to psychological stress. The abundant anecdotal evidence of hair graying overnight (or, as Shakespeare put it in Henry IV: “Thy father’s beard is turned
Diluting Blood Plasma Rejuvenates Old Mice
June 16, 2020
Back in 2005, Drs. Irina and Michael Conboy showed that joining the circulatory systems of young and old mice together in a procedure called parabiosis could rejuvenate aged tissues and reverse some aspects of aging in old mice. Following this discovery, many researchers concluded that there
Removing Some Senescent Cells May Have Consequences
June 15, 2020
Senescent cell accumulation is a likely reason we age, but removing some populations of specialized cells that have turned senescent may have negative consequences, according to a new study. What are senescent cells? As you get older, more and more of your cells enter into a
NAD+ Restores Mitochondrial Function in Egg Cells
June 11, 2020
Researchers have discovered that a lack of NAD+ is responsible for mitochondrial dysfunction in egg cells (oocytes), leading to decreased fertility with age. Mitochondria in oocytes Given how much it must divide to create a human being, the oocyte is the largest cell in the human
Niacin May Prove Useful Against Brain Cancer
June 10, 2020
A possible new role for niacin has been discovered in the fight against brain cancer. An old vitamin Niacin is a form of vitamin B3 and has been a popular supplement since its discovery in 1937 by the researcher Conrad Elvehjem. Niacin is actually nicotinic acid,
A New Likely Mechanism Behind Osteoporosis Discovered
June 9, 2020
A group of Japanese scientists has found that advanced glycation end products (AGEs) tend to accumulate in osteoblasts with age, inducing apoptosis via endoplasmic reticulum stress. This mechanism likely contributes to the development of osteoporosis [1]. AGEs and age Advanced glycation end-products, fittingly abbreviated as AGEs,
Niacin Increases NAD+ Significantly in Human Trial
June 8, 2020
Researchers have concluded a human trial using niacin, a very old vitamin discovered over 80 years ago, and have shown that it can increase the presence of an energy compound essential to cellular function. Niacin and NAD+ Niacin is a form of water-soluble vitamin B3 and
Why I Am Still Future Positive on My Birthday
June 5, 2020
Don’t let your birthday get you down and remind you that you are getting older; there are plenty of reasons to be cheerful about the future and your place in it, especially as science is now turning its attention to aging. Another trip around the sun
Update from CellAge
June 4, 2020
Today is one of those days when we must deliver some bad news. Science is hard, particularly when it concerns the biology of aging, and things do not always go to plan. There are no guarantees that a project will succeed, and, quite simply, the more