Lifespan Research Institute

Category: News

Disappointment

Disappointing Results for ResTORbio Human Trial

ResTORbio announced on Friday 15th that its current phase 3 drug trial for respiratory tract infections did not achieve its primary goal. The drug showed promise in earlier phases of

SKM and OSKM

Excluding Oct4 from OSKM Yields Positive Results

A recent open-access study published in Cell Stem Cell has shown that excluding Oct4 from the OSKM cocktail reduces epigenetic aberrations and off-target gene activation. Induced pluripotency and Yamanaka factors

Fat mouse

Combination Gene Therapy Treats Many Age-Related Diseases

A team of researchers, including renowned geneticist Professor George Church, has published a new paper demonstrating the mitigation of multiple age-related diseases using a multi-target gene therapy. Treating multiple age-related

Greg Fahy

Dr. Greg Fahy Appears on The Damage Report

Dr. Greg Fahy, Chief Scientific Officer of Intervene Immune, has recently appeared on The Damage Report, a news and current events show that is part of The Young Turks (TYT)

Framework

A New Healthcare Framework for Aging Populations

A new publication by an international team of scientists has proposed a new healthcare framework to help older people stay healthier for longer by improving the development of therapies that

double strand break

DNA Damage Leads to Epigenetic Alterations

A team of researchers, including Dr. David Sinclair, has recently made a new study available as a preprint prior to peer review and publication in the journal Cell. DNA damage

Eye

GenSight Biologics Releases Further Trial Data

GenSight Biologics has recently released data showing the effectiveness of GS010, the company’s gene therapy for Leber Hereditary Optic Neuropathy (LHON), a mitochondrial disease that can lead to blindness. Like

Justin Rebo Interview

Justin Rebo on BioAge and Biotech

At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge. BioAge is developing

Rejuvenation Roundup September

Rejuvenation Roundup September 2019

With a new month ahead and an old one behind, it’s again time to review the latest news and progress in the field of rejuvenation biotechnology. There’s a number of

Michael West Interview

Michael West Discusses AgeX Therapeutics

At our 2019 Ending Age-related Diseases conference in New York City, we had the pleasure of speaking with Dr. Michael West, the CEO of AgeX Therapeutics. Dr. West can rightfully

Synthetic organs

SWIFT Provides Synthetic Organ Breakthrough

The ability to create synthetic organs has long been desired in medicine. If we could make synthetic organs for patients from their own cells, we could replace injured or damaged

Colombia

Irresponsible Marketing Surrounds Telomerase Trials

Recently, Libella Gene Therapeutics has announced that it will be running a patient-paid trial in Colombia with an eye-watering $1 million USD price tag on enrollment. Patient-paid trial likely to cause backlash The topic of patient-paid trials often stirs up considerable debate among the research community,

gut brain axis diagram

Gut Microbes Promote Neurogenesis and Longevity Hormone

The relationship between health and the microorganisms living in the gut has increasingly reached the spotlight in the last few years, and a new study led by researchers at Nanyang Technological University, Singapore (NTU Singapore) sheds more light on the gut microbiome and how it can

Disappointment

Disappointing Results for ResTORbio Human Trial

ResTORbio announced on Friday 15th that its current phase 3 drug trial for respiratory tract infections did not achieve its primary goal. The drug showed promise in earlier phases of testing, but sadly failed to reduce the incidence of respiratory tract infections in patients aged 65

SKM and OSKM

Excluding Oct4 from OSKM Yields Positive Results

A recent open-access study published in Cell Stem Cell has shown that excluding Oct4 from the OSKM cocktail reduces epigenetic aberrations and off-target gene activation. Induced pluripotency and Yamanaka factors Pluripotent stem cells are cells that can become other cell types in the body; during natural

Fat mouse

Combination Gene Therapy Treats Many Age-Related Diseases

A team of researchers, including renowned geneticist Professor George Church, has published a new paper demonstrating the mitigation of multiple age-related diseases using a multi-target gene therapy. Treating multiple age-related diseases at once George Church is a very prominent figure in genetics and aging research, and

gut brain axis diagram

Tweaking Gut Bacteria to Reduce Cognitive Decline

A new paper explores adjusting the types of bacteria in the gut as a potential way to improve health in older people. The microbiome The gut microbiome is a fascinating and diverse ecosystem filled with a myriad of bacteria, archaea, protists, fungi, and viruses that interact

Greg Fahy

Dr. Greg Fahy Appears on The Damage Report

Dr. Greg Fahy, Chief Scientific Officer of Intervene Immune, has recently appeared on The Damage Report, a news and current events show that is part of The Young Turks (TYT) network. Hosts John Iadarola and Brooke Thomas talked with Dr. Fahy about the recent positive results

Framework

A New Healthcare Framework for Aging Populations

A new publication by an international team of scientists has proposed a new healthcare framework to help older people stay healthier for longer by improving the development of therapies that target age-related diseases. Society is aging, and we need to change healthcare for the better This

Ronald Kohanski Interview

Ronald Kohanski of the NIA Discusses Potential Therapies

It was a pleasure speaking to Dr. Ronald Kohanski at the 2019 Ending Age-Related Diseases conference. Dr. Kohanski joined the field of aging research in 2005 as a Program Officer for the Division of Aging Biology at the National Institute on Aging. He moved on to

double strand break

DNA Damage Leads to Epigenetic Alterations

A team of researchers, including Dr. David Sinclair, has recently made a new study available as a preprint prior to peer review and publication in the journal Cell. DNA damage and the double-strand break Two of the primary hallmarks of aging are genomic instability, which consists

Eye

GenSight Biologics Releases Further Trial Data

GenSight Biologics has recently released data showing the effectiveness of GS010, the company’s gene therapy for Leber Hereditary Optic Neuropathy (LHON), a mitochondrial disease that can lead to blindness. Like in previous studies, this therapy had a bilateral effect. Gene Therapy In LHON, the mitochondrial protein

Justin Rebo Interview

Justin Rebo on BioAge and Biotech

At the Ending Age-Related Diseases 2019 Conference in New York City, we had the opportunity to interview Dr. Justin Rebo from the drug discovery biotech company BioAge. BioAge is developing a drug discovery platform that uses machine learning and artificial intelligence to discover targets that have

Rejuvenation Roundup September

Rejuvenation Roundup September 2019

With a new month ahead and an old one behind, it’s again time to review the latest news and progress in the field of rejuvenation biotechnology. There’s a number of past events to look back upon, including Age-Related Diseases 2019, and upcoming ones to look forward

Michael West Interview

Michael West Discusses AgeX Therapeutics

At our 2019 Ending Age-related Diseases conference in New York City, we had the pleasure of speaking with Dr. Michael West, the CEO of AgeX Therapeutics. Dr. West can rightfully be called a pioneer in his field with a substantial background in biomedical and biotechnology corporations.

Synthetic organs

SWIFT Provides Synthetic Organ Breakthrough

The ability to create synthetic organs has long been desired in medicine. If we could make synthetic organs for patients from their own cells, we could replace injured or damaged organs without risking the body rejecting the organ. This would have huge implications for the treatment