Category: News
Macrophages Become Scars in the Heart
February 6, 2020
A paper published in Nature Communications reveals that, rather than just summoning fibroblasts, inflammatory macrophages themselves form fibrous tissue that is the basis of scars. The dual role of macrophages
Irina & Michael Conboy – Making Old Blood Young Again
February 5, 2020
We were at the recent Longevity Therapeutics Conference in San Francisco, and we had the opportunity to interview Irina and Michael Conboy from UC Berkeley about their pioneering work on
Refining the Allotopic Expression of Mitochondrial Genes
February 4, 2020
Researchers from SENS Research Foundation, including Matthew O’Connor and Amutha Boominathan, have published a new study showing how codons play an important role in getting copies of mitochondrial genes placed
Rejuvenation Roundup January 2020
February 3, 2020
2020 has been a common year to define the beginning of “the future”, so now’s a great time to discover just how close real biotechnology has come to popular expectations.
Results From a Human Trial for Skin Aging
February 2, 2020
The January edition of Journal Club, hosted by Dr. Oliver Medvedik, took a look at the results of a recent human trial in which the drug rapamycin was used to
Mitochondria Found Independently Living in Blood
January 27, 2020
The mitochondria are well known as being the powerhouses of the cell, as they convert nutrients into the energy that our cells need in order to function and remain alive.
Three Groundbreaking Longevity Startups
January 9, 2020
There are lots of exciting companies working in the aging field, and it’s a great time to tell you about three of the more interesting ones. Most of these companies
Revel Pharma to Develop Glucosepane Breakers
January 8, 2020
Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why
Treating Glaucoma with Senolytics
January 6, 2020
New research suggests that senolytic drugs, which remove harmful senescent cells that accumulate during aging, may be an effective therapy for glaucoma, a common age-related condition that leads to loss
Looking Back at 2019 – and Forward to 2020
January 3, 2020
2019 is quite a milestone for LEAF; this will be our fourth year of bringing you the latest industry news, organizing online events, hosting our annual conference in New York,
Anti-Aging Drug Rejuvenates Oral Health
December 19, 2019
A new study shows that short-term treatment with the common organ rejection drug rapamycin reverses periodontal bone loss, attenuates inflammation, and makes the oral microbiome revert to a more youthful
Greg Potter on Biohacking and Lifestyle
December 17, 2019
We had the opportunity to interview Greg Potter, Ph.D., a researcher of lifestyle factors in health throughout life, at Biohacking Conference Moscow, which was hosted at the Congress Centre Technopolis
Tryptophan as a Therapeutic Target for Inflammaging
December 9, 2019
A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes
DNA Testing Company Veritas Genetics Suspends U.S. Operations
December 6, 2019
After experiencing financial issues, DNA testing company Veritas Genetics has announced the suspension of its U.S. operations in an unexpected announcement on December 4th 2019. The company is perhaps best
Brian Kennedy on Rapamycin, mTOR, and Interventions
December 4, 2019
If humans ever reach an average lifespan of well over 100 years, what is going to happen? Are we going to be bored with such long lives? “Well,” says Prof.
Macrophages Become Scars in the Heart
February 6, 2020
A paper published in Nature Communications reveals that, rather than just summoning fibroblasts, inflammatory macrophages themselves form fibrous tissue that is the basis of scars. The dual role of macrophages Macrophages perform two critical roles in the immune system. After an injury, M1 macrophages spur local
Irina & Michael Conboy – Making Old Blood Young Again
February 5, 2020
We were at the recent Longevity Therapeutics Conference in San Francisco, and we had the opportunity to interview Irina and Michael Conboy from UC Berkeley about their pioneering work on blood factors and aging. Irina is a member of our Scientific Advisory Board, and the Conboys’
Refining the Allotopic Expression of Mitochondrial Genes
February 4, 2020
Researchers from SENS Research Foundation, including Matthew O’Connor and Amutha Boominathan, have published a new study showing how codons play an important role in getting copies of mitochondrial genes placed in the cellular nucleus to express themselves correctly [1]. A possible solution to mitochondrial diseases Mitochondrial
Rejuvenation Roundup January 2020
February 3, 2020
2020 has been a common year to define the beginning of “the future”, so now’s a great time to discover just how close real biotechnology has come to popular expectations. To kick off the first month of the new year, we have plenty of research to
Results From a Human Trial for Skin Aging
February 2, 2020
The January edition of Journal Club, hosted by Dr. Oliver Medvedik, took a look at the results of a recent human trial in which the drug rapamycin was used to treat skin aging with some promising results.
Mitochondria Found Independently Living in Blood
January 27, 2020
The mitochondria are well known as being the powerhouses of the cell, as they convert nutrients into the energy that our cells need in order to function and remain alive. Until recently, it was believed that they remain within our cells all their lives, but a
Three Groundbreaking Longevity Startups
January 9, 2020
There are lots of exciting companies working in the aging field, and it’s a great time to tell you about three of the more interesting ones. Most of these companies are a while away from human trials yet, but their innovations could possibly be truly game
Revel Pharma to Develop Glucosepane Breakers
January 8, 2020
Some pleasant news has recently arrived: Revel Pharmaceuticals has successfully completed a seed round in order to begin developing therapeutics that target glucosepane crosslinks, which are a proposed reason why we age, develop diseases such as diabetes, and suffer from stiffened arteries and hypertension. In the
Treating Glaucoma with Senolytics
January 6, 2020
New research suggests that senolytic drugs, which remove harmful senescent cells that accumulate during aging, may be an effective therapy for glaucoma, a common age-related condition that leads to loss of vision. In the short term, inflammation serves a useful purpose, as it helps to spur
Looking Back at 2019 – and Forward to 2020
January 3, 2020
2019 is quite a milestone for LEAF; this will be our fourth year of bringing you the latest industry news, organizing online events, hosting our annual conference in New York, and crowdsourcing important research projects over at Lifespan.io. We have been incredibly busy and, as has
Anti-Aging Drug Rejuvenates Oral Health
December 19, 2019
A new study shows that short-term treatment with the common organ rejection drug rapamycin reverses periodontal bone loss, attenuates inflammation, and makes the oral microbiome revert to a more youthful state in old mice. What is rapamycin? Rapamycin (also known as sirolimus) is a macrolide, a
Greg Potter on Biohacking and Lifestyle
December 17, 2019
We had the opportunity to interview Greg Potter, Ph.D., a researcher of lifestyle factors in health throughout life, at Biohacking Conference Moscow, which was hosted at the Congress Centre Technopolis Moscow on September 19th. In a provocative 2017 publication, Serge Faguet claimed to have spent $200,000
Tryptophan as a Therapeutic Target for Inflammaging
December 9, 2019
A new open access paper takes a look at tryptophan and the role that it plays in the dysfunction of the immune system in the context of the age-related changes that occur in the microbiome [1]. The microbiome The gut microbiome is a complex ecosystem of
DNA Testing Company Veritas Genetics Suspends U.S. Operations
December 6, 2019
After experiencing financial issues, DNA testing company Veritas Genetics has announced the suspension of its U.S. operations in an unexpected announcement on December 4th 2019. The company is perhaps best known for being co-founded by renowned Harvard University geneticist George Church and has been working towards
Brian Kennedy on Rapamycin, mTOR, and Interventions
December 4, 2019
If humans ever reach an average lifespan of well over 100 years, what is going to happen? Are we going to be bored with such long lives? “Well,” says Prof. Brian Kennedy of the National University of Singapore, “If you ask me: ‘Do I want to