Category: News
From Within Your Own Failing Shell
September 7, 2018
Some time ago, I noticed a stock photo of an old lady seeing her geriatrician, who was a much younger woman. Nothing special was happening in the picture, which showed
Administering Gene Therapy Without Triggering Immune Response
September 6, 2018
Scientists at Stanford University School of Medicine managed to administer effective gene therapy in mice without triggering an autoimmune reaction. The research, led by Dr. Peggy Ho, Ph.D., was published
A Review of Cellular Senescence and Senolytics
September 6, 2018
Today, we want to point out a new publication that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist
NAD+ Repletion Shows Potential Against Aging
September 5, 2018
Science is advancing rapidly, and the field of aging research is no exception. Our understanding of aging has grown a great deal in the last decade, and we are now
An Interview With David Gobel
September 5, 2018
David Gobel is an inventor, philanthropist, futurist, and passionate rejuvenation advocate and supporter; he’s known for co-founding Methuselah Foundation with Dr. Aubrey de Grey and for proposing the intriguing concept
DNA Replication Can Happen Without ORC1
September 4, 2018
According to a study conducted by Hollings Cancer Center scientists at the Medical University of South Carolina, DNA replication in murine cells is possible even in the absence of origin
Rejuvenation Roundup August 2018
September 3, 2018
We hope August has treated you well—it certainly did so for life extension, as this has been another month full of great news for the field. Don’t be upset with
Getting Aging Classified as a Disease – Daria Khaltourina
August 31, 2018
We are pleased to report that lobbyists have made more progress towards classifying aging as a disease. The World Health Organization (WHO) has implemented the extension code ‘Ageing-related’ (XT9T) in
Alexandra Elbakyan – The System is Holding Back Scientific Progress
August 28, 2018
Today, we have an interview with Sci-Hub creator Alexandra Elbakyan, who is committed to the free flow of scientific knowledge and is challenging the unfair journal system, which charges outrageous
Telomerase Gene Therapy Does Not Increase Cancer Risk
August 27, 2018
Researchers have demonstrated that telomerase gene therapy does not increase the risk of cancer, even in strains of mice that are particularly susceptible to cancer [1]. A tale of telomeres
Dr. Irina Conboy Joins the LEAF Scientific Advisory Board
August 17, 2018
We are growing fast as an organization thanks to the support of the community, particularly our monthly patrons, the Lifespan Heroes. We are delighted to announce that another respected scientist,
An Interview With Didier Coeurnelle
August 15, 2018
As you might remember, we have recently posted about the Longevity Film Competition, an initiative by HEALES, ILA, and the SENS Research Foundation that encourages supporters of healthy life extension
Glucose and the Gut Microbiome
August 9, 2018
Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract
Samumed in $438 Million Deal to Develop Anti-aging Therapies
August 8, 2018
Today, we were pleased to hear that Samumed, a San Diego-based biotech company working on regenerative medicine, has just raised $438 million towards developing anti-aging therapies. SAN DIEGO – August
Whatever Future Comes, Life Extension Will Improve It
August 8, 2018
Right now, as I write this article, I’m sitting in a machine that, about 120 years ago, was laughed at as a pipe dream. The machine is a plane, by
From Within Your Own Failing Shell
September 7, 2018
Some time ago, I noticed a stock photo of an old lady seeing her geriatrician, who was a much younger woman. Nothing special was happening in the picture, which showed just two people talking; however, it made me wonder what it must feel like to be
Administering Gene Therapy Without Triggering Immune Response
September 6, 2018
Scientists at Stanford University School of Medicine managed to administer effective gene therapy in mice without triggering an autoimmune reaction. The research, led by Dr. Peggy Ho, Ph.D., was published in the Proceedings of the National Academy of Sciences [1]. Study abstract In gene therapy for
A Review of Cellular Senescence and Senolytics
September 6, 2018
Today, we want to point out a new publication that dives into the world of senolytics, which are drugs or therapies that seek and destroy harmful non-dividing cells that resist the programmed cell death known as apoptosis. These cells linger in the body, and, as we
NAD+ Repletion Shows Potential Against Aging
September 5, 2018
Science is advancing rapidly, and the field of aging research is no exception. Our understanding of aging has grown a great deal in the last decade, and we are now reaching the point at which the first therapies that target aging are starting to arrive. Unlike
An Interview With David Gobel
September 5, 2018
David Gobel is an inventor, philanthropist, futurist, and passionate rejuvenation advocate and supporter; he’s known for co-founding Methuselah Foundation with Dr. Aubrey de Grey and for proposing the intriguing concept of “longevity escape velocity”, but his achievements and successes extend far beyond that. David has kindly
DNA Replication Can Happen Without ORC1
September 4, 2018
According to a study conducted by Hollings Cancer Center scientists at the Medical University of South Carolina, DNA replication in murine cells is possible even in the absence of origin recognition complex 1 (ORC1), a protein encoded by the homonymous gene that was previously thought to
Rejuvenation Roundup August 2018
September 3, 2018
We hope August has treated you well—it certainly did so for life extension, as this has been another month full of great news for the field. Don’t be upset with the departure of summer and the arrival of autumn, because little by little, we’re getting close
Getting Aging Classified as a Disease – Daria Khaltourina
August 31, 2018
We are pleased to report that lobbyists have made more progress towards classifying aging as a disease. The World Health Organization (WHO) has implemented the extension code ‘Ageing-related’ (XT9T) in the latest version of the International Classification of Diseases (ICD). The inclusion of the new code
Alexandra Elbakyan – The System is Holding Back Scientific Progress
August 28, 2018
Today, we have an interview with Sci-Hub creator Alexandra Elbakyan, who is committed to the free flow of scientific knowledge and is challenging the unfair journal system, which charges outrageous fees to view scientific publications. Hiding scientific knowledge behind paywalls Around 70% of scientific publications are
Telomerase Gene Therapy Does Not Increase Cancer Risk
August 27, 2018
Researchers have demonstrated that telomerase gene therapy does not increase the risk of cancer, even in strains of mice that are particularly susceptible to cancer [1]. A tale of telomeres Short telomeres trigger cellular senescence and are thought to be one of the primary hallmarks of
Dr. Irina Conboy Joins the LEAF Scientific Advisory Board
August 17, 2018
We are growing fast as an organization thanks to the support of the community, particularly our monthly patrons, the Lifespan Heroes. We are delighted to announce that another respected scientist, Dr. Irina Conboy, has joined our scientific advisory board and will be providing us with expert
An Interview With Didier Coeurnelle
August 15, 2018
As you might remember, we have recently posted about the Longevity Film Competition, an initiative by HEALES, ILA, and the SENS Research Foundation that encourages supporters of healthy life extension to produce a short film to popularize the subject. Didier Coeurnelle is a jurist and the
Glucose and the Gut Microbiome
August 9, 2018
Somewhat serendipitously, Salk Institute researchers discovered that depleting the microbiomes of mice causes the animals to have lower levels of blood glucose as well as improved insulin sensitivity [1]. Abstract Antibiotic-induced microbiome depletion (AIMD) has been used frequently to study the role of the gut microbiome
Samumed in $438 Million Deal to Develop Anti-aging Therapies
August 8, 2018
Today, we were pleased to hear that Samumed, a San Diego-based biotech company working on regenerative medicine, has just raised $438 million towards developing anti-aging therapies. SAN DIEGO – August 6, 2018 – Samumed, LLC, announced today that it has closed its A-6 Round of equity
Whatever Future Comes, Life Extension Will Improve It
August 8, 2018
Right now, as I write this article, I’m sitting in a machine that, about 120 years ago, was laughed at as a pipe dream. The machine is a plane, by the way. The onboard wi-fi leaves much to be desired, but if you had told people