Lifespan Research Institute

Category: News

Elderly eating healthy

The Relationship Between Diet and Senescence

An extremely comprehensive review published in Food Science & Biotechnology has summarized the current state of research regarding cellular senescence and basic dietary components. An aging-focused outlook The researchers begin

Strong mouse

Stem Cells for Fighting Sarcopenia

In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple

Ovary follicle

Targeting Fibrosis Reverses Ovarian Aging in Mice

Scientists have successfully treated ovarian aging in mice with compounds that target fibrosis and promote mitochondrial health [1]. Why do ovaries age faster? Ovarian aging is fascinating because one bodily

Naked mole rats natural habitat

Skin Aging of the Naked Mole Rat

Naked mole rats are long-lived rodents famous for their resistance to cancer and sustained healthy lifespan. In a new study published in the Journal of Investigative Dermatology, researchers have shown

Blood donation

Blood Donation Slows Skin Aging in Mice

Scientists have shown that blood donation strongly affects skin aging in mice, probably by lowering the levels of toxic free iron [1]. The good bloodshed Before the dawn of modern

Fly eye

Dietary Restriction Delays Eye Aging in Flies

A new study published in Nature has reported on how caloric restriction, circadian rhythms, and molecular clocks interact to affect the ocular health and lifespan of fruit flies. Circadian rhythms,

Missed target

Spermidine Human Trial Results Fail to Impress

The results of a human clinical trial for spermidine against cognitive decline have recently been published, but the results are not positive. What is spermidine? Spermidine is a polyamine, meaning

Elderly eating healthy

The Relationship Between Diet and Senescence

An extremely comprehensive review published in Food Science & Biotechnology has summarized the current state of research regarding cellular senescence and basic dietary components. An aging-focused outlook The researchers begin their paper with a discussion of aging, citing a paper that frames it in terms of

Senolytic Helps Anti-Osteoarthritis Potential in Stem Cells

Scientists have improved the potential effectiveness of a stem cell therapy for osteoarthritis by targeting senescent cells [1]. Stem cell exhaustion and osteoarthritis Osteoarthritis is an age-related disease that affects joints by degrading cartilage. While not fatal in itself, osteoarthritis negatively affects mobility and quality of

Strong mouse

Stem Cells for Fighting Sarcopenia

In their publication in Stem Cell Research & Therapy, a team of researchers has shown how effective mesenchymal stromal cells (MSCs) are in a mouse model. Multipotent cells with multiple uses As multipotent stem cells, MSCs can differentiate into several different cell types, including fat cells,

Heart and Brain

Aspirin Affects Alzheimer’s Outcomes in Cardiac Patients

A study published in Alzheimer’s Research & Therapy has shown that low-dose aspirin affects Alzheimer’s disease and vascular dementia only in the presence of coronary heart disease. A well-known preventative Acetylsalicylic acid, more commonly known as aspirin, is often taken at a steady, low dose of

Ovary follicle

Targeting Fibrosis Reverses Ovarian Aging in Mice

Scientists have successfully treated ovarian aging in mice with compounds that target fibrosis and promote mitochondrial health [1]. Why do ovaries age faster? Ovarian aging is fascinating because one bodily system completely shuts down while the rest of the body is still in good health. Therefore,

Omega 3 B Vitamin Foods

B Vitamins and Omega-3 Fatty Acids Against Cognitive Decline

Researchers publishing in the European Journal of Nutrition have discovered that a combination of B vitamins and the omega-3 fatty acid DHA is linked to decreased cognitive decline in older individuals. A post-hoc analysis of previous results The researchers came to their conclusion after analyzing the

Naked mole rats natural habitat

Skin Aging of the Naked Mole Rat

Naked mole rats are long-lived rodents famous for their resistance to cancer and sustained healthy lifespan. In a new study published in the Journal of Investigative Dermatology, researchers have shown that the skin of older members of this species is characterized by high expression of longevity-associated

Blood donation

Blood Donation Slows Skin Aging in Mice

Scientists have shown that blood donation strongly affects skin aging in mice, probably by lowering the levels of toxic free iron [1]. The good bloodshed Before the dawn of modern medicine, bloodletting was one of the favorite arrows in medieval doctors’ quivers. Of course, it was

Fly eye

Dietary Restriction Delays Eye Aging in Flies

A new study published in Nature has reported on how caloric restriction, circadian rhythms, and molecular clocks interact to affect the ocular health and lifespan of fruit flies. Circadian rhythms, clock genes, and photoreceptors The researchers begin their paper by discussing the concept of circadian rhythms,

Breast cancer

Scientists Discover Therapy Against Aggressive Breast Cancer

Publishing in Nature, scientists from the University of Texas report the discovery of a small molecule that can stop an especially aggressive subtype of breast cancer [1]. The deadliest kind Breast cancer remains the fourth deadliest type of cancer, claiming more than 40 thousand victims a

Old woman in sunlight

Vitamin D Supplements Linked to Slower Epigenetic Aging

Using a Berlin cohort, a study published in GeroScience has uncovered a link between Vitamin D supplementation and a reduction of epigenetic age. On the back of previous work This study’s cohort consisted of 60- to 85-year-old participants in the Berlin Aging Study II (BASE-II). The

Fish Heavy Diet

Mediterranean Diet Associated with Lifespan and Healthspan

Scientists have shown yet again that adherence to the Mediterranean diet is positively correlated with longer and healthier lives – this time in a large-scale population study spanning 130 countries [1]. Olive oil in, meat mostly out The so-called Mediterranean diet is one of the most

Exercising Elderly

Urolithin A Improves Muscle Strength in Middle-Aged Adults

A new study published in Cell Reports Medicine shows that urolithin A supplementation improves muscle strength, fitness, and mitochondrial health in overweight, middle-aged adults [1]. Mitophagy in aging and in disease Mitochondrial dysfunction is one of the hallmarks of aging. It is associated with age-related skeletal

Weight Loss

Drug Leads to Drastic Weight Loss With Diet and Exercise

A large Phase 3 study published in the New England Journal of Medicine shows that an existing drug combined with a healthy diet and mild exercise leads to an average weight loss of 20% [1]. Diet and exercise are not always enough Being a known comorbid

Missed target

Spermidine Human Trial Results Fail to Impress

The results of a human clinical trial for spermidine against cognitive decline have recently been published, but the results are not positive. What is spermidine? Spermidine is a polyamine, meaning it has two or more primary amino groups. It is naturally occurring and is widely encountered