Lifespan Research Institute

Category: News

Telomeres

A New Understanding of Telomere Attrition

In Nature Cell Biology, a team of researchers has presented a current review of telomeres and how they relate to aging, reflecting modern research into a decades-old topic. Telomeres and

Life Noggin has joined the Lifespan.io family.

Life Noggin Joins the Lifespan.io Family

Today, we are delighted to officially announce that the popular pop-sci Youtube channel, Life Noggin, has joined the Lifespan.io family. To celebrate the official launch, we are pleased to reveal

Rainbow Clocks

A Fresh Examination of Epigenetic Clocks

In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks

Seniors walking

Muscular Oxidative Capacity Predicts Mobility Decline

Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the

Hand arthritis

New Treatment for Osteoarthritis Proposed

In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer,

Pueraria

Puerarin Shows Promise in Fighting COPD in Cells

Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption

Debate

Researcher Offers A Critique of Geroscience

Eric Le Bourg has published a thought-provoking paper in Biogerontology that offers a critique of geroscience [1]. Geroscience, we need to talk… When people discuss the prospects of targeting the

EARD2021 Irina Conboy

Irina Conboy on Heterochronic Plasma at EARD2021

At Ending Age-Related Diseases 2021, Irina Conboy discussed the effects of plasma dilution and heterochronic plasma exchange and their relationship to epigenetic alterations. Script Thank you for inviting me again,

Skeletal Muscle

Urolithin A Affects Muscle and Mitochondria in Older Adults

A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial  This study is a

Exercising man

NAD+ Levels Are Correlated with Physical Activity in Humans

In a study published in Nature Aging, a group of scientists has shown that NAD+ levels are correlated not only with age but with physical activity, with elder athletes rivaling normal young adults [1]. NAD: small, crucial, age-related Nicotinamide adenine dinucleotide (NAD) is as important as

Pankaj Kapahi Interview

Dr. Pankaj Kapahi: “AGEs are a Trillion-Dollar Industry”

Dr. Pankaj Kapahi is a veteran geroscientist. His laboratory at the famous Buck Institute for Research on Aging is among the few that study advanced glycation end products (AGEs) and the many ways in which they affect aging. Dr. Kapahi’s company, Juvify, produces GLYLO, a supplement

Telomeres

A New Understanding of Telomere Attrition

In Nature Cell Biology, a team of researchers has presented a current review of telomeres and how they relate to aging, reflecting modern research into a decades-old topic. Telomeres and cellular senescence This paper touches upon senescent cells and the senescence-associated secretory phenotype (SASP) that they

Life Noggin has joined the Lifespan.io family.

Life Noggin Joins the Lifespan.io Family

Today, we are delighted to officially announce that the popular pop-sci Youtube channel, Life Noggin, has joined the Lifespan.io family. To celebrate the official launch, we are pleased to reveal a new episode of Life Noggin that focuses on some unexpected sources of life extension that

Fat and skinny

Caloric Restriction Promotes Rejuvenation in Human Trials

In a new paper, Yale scientists present encouraging data from an unprecedented human study of caloric restriction, a powerful anti-aging intervention [1]. Eat less, live more Despite all the might of today’s science, simple lifestyle choices are still the clearest option for living longer and healthier.

Rainbow Clocks

A Fresh Examination of Epigenetic Clocks

In a preprint published in bioRxiv, Morgan Levine and colleagues have identified and grouped 5,717 epigenetic CpG sites into 12 different modules, conducting an in-depth examination into how epigenetic clocks work. What is a CpG site? Methylation cannot occur everywhere in the genome. The researchers explain

Seniors walking

Muscular Oxidative Capacity Predicts Mobility Decline

Researchers publishing in Aging Cell have shown a relationship between mitochondrial dysfunction and mobility decline in older adults. A changing longitudinal study Since 1958, a team of researchers from the National Institute on Aging Intramural Research program has been conducting the Baltimore Longitudinal Study of Aging

Hand arthritis

New Treatment for Osteoarthritis Proposed

In a paper published in Nature Aging, a group of scientists outlines a previously unknown pathway that leads to osteoarthritis and describes a promising treatment [1]. Less than a killer, more than a nuisance There are plenty of deadly age-related diseases, and then there are others

Pueraria

Puerarin Shows Promise in Fighting COPD in Cells

Publishing in Aging, a team of researchers has discovered how puerarin, an extract of kudzu, ameliorates chronic obstructive pulmonary disorder (COPD) signs in cellular cultures by limiting mitophagy: the consumption of mitochondria by cells. When autophagy isn’t a good thing Mitophagy is a subset of autophagy,

New Biotech

New Partial Reprogramming Drastically Lowers Cellular Age

In a pre-print paper that has not yet been peer reviewed, a group of researchers presented a new highly efficient method of partial cellular reprogramming [1]. Young from old Our cells age, and old cells differ from young ones in multiple ways, including gene expression, telomere

Work Stress

Debunking Myths About Work Stress and Age Acceleration

A study published in Aging that studied the Northern Finland Birth Cohort of 1966 has found some interesting and counterintuitive results regarding work stress and accelerated epigenetic aging. Work stress is widely associated with premature death It is common folk wisdom that too much stress leads

Debate

Researcher Offers A Critique of Geroscience

Eric Le Bourg has published a thought-provoking paper in Biogerontology that offers a critique of geroscience [1]. Geroscience, we need to talk… When people discuss the prospects of targeting the aging processes to prevent, halt, or even reverse age-related diseases, their beliefs often fall into two

EARD2021 Irina Conboy

Irina Conboy on Heterochronic Plasma at EARD2021

At Ending Age-Related Diseases 2021, Irina Conboy discussed the effects of plasma dilution and heterochronic plasma exchange and their relationship to epigenetic alterations. Script Thank you for inviting me again, it’s much appreciated. This is an excellent conference series. I will start by telling you that

Mankai

A Polyphenol-Rich Diet Reduces Age-Related Cognitive Decline

A preprint study originating from the DIRECT PLUS trial was recently released from the American Journal of Clinical Nutrition [1]. This study has been accepted into the journal but has not yet been peer reviewed. Duckweed for health This study focused on a plant called Mankai,