Lifespan Research Institute

Category: News

Synaptic Transmission

New Combination Treatment Shows Promise Against Dementia

Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer’s disease, still defy

Hand arthritis

Osteopontin Bone Remodeling May Be Key to Arthritis

A study published in Aging has found that osteopontin’s effects on bone remodeling may be at least partially responsible for osteoarthritis. What is osteopontin? Osteopontin is a glycoprotein found in

Rejuvenation Roundup image

Rejuvenation Roundup December 2021

2021 has come to a close, but rejuvenation biotechnology is still just beginning. Let’s see what the field has accomplished in December. LEAF News Holiday Wishes from Lifespan.io: Lifespan.io president

Sleeping Old Man

A Link Between the Circadian Rhythm and Aging

A new study published in Aging has shown a relationship between the circadian clock and the changes in gene expression with age. Two complex systems and four distinct species This

Gitcoin GR12 funding round for longevity.

Gitcoin GR12 Is a Win-Win for Aging Research

In recent years, the cryptocurrency community has become increasingly interested in the drive to increase healthy human lifespans. Gitcoin introduces longevity research into its funding rounds  Gitcoin recently held its

Uterus

NMN Slows Ovarian Aging in Mice

Scientists have found that long-term supplementation with NMN, an NAD+ precursor, dramatically slows reproductive aging in mice by improving mitochondrial function and alleviating senescence [1]. Reproductive aging affects women relatively

Vaccination

A Potential Vaccine for Senescent Cells

The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the

Christmas Fireplace

Happy Holidays from Lifespan.io

Dear Friends, As we close out the year and continue the holiday season, I want to take this opportunity to thank you for being part of our community at Lifespan.io

Debate

Debate Rages on the Inclusion of Old Age in the ICD-11

A significant debate has originated regarding the inclusion of MG2A, a code for old age, in the ICD-11 for Mortality and Morbidity Statistics. What is the ICD-11? The 11th revision of the International Classification of Diseases, which goes into effect this month, is managed by the

Synaptic Transmission

New Combination Treatment Shows Promise Against Dementia

Scientists have combined the popular antibiotic rifampicin with resveratrol to create a possible preventative treatment for age-related dementias [1]. Oligomers, not plaques? Age-related dementias, such as Alzheimer’s disease, still defy current treatment options, impeding attempts to increase human lifespan. According to the theory of competing risks,

Hand arthritis

Osteopontin Bone Remodeling May Be Key to Arthritis

A study published in Aging has found that osteopontin’s effects on bone remodeling may be at least partially responsible for osteoarthritis. What is osteopontin? Osteopontin is a glycoprotein found in the extracellular matrix of bone tissue. This is a cytokine that is used in intercellular communication,

Spinach leaves

Supplement Combo Boosts Working Memory in Older People

An open-access human study published in Clinical Nutrition has found that a combination of supplements is beneficial for working memory. Identifying the dietary compounds Specific types of eating patterns have been associated with improved memory and cognition. The authors highlight some of the specific dietary components

Heart and veins

The Effects of Spermidine on Heart Mitochondria in Mice

The latest research published in the Journal of Anatomy found that spermidine alters the morphology of mitochondria in aged mouse heart tissue [1]. Mitochondrial dysfunction in the aging heart Evidence for mitochondrial dysfunction as a driver of aging has been growing in recent years. As we

AL4I Panel

Creating Political Action to Increase Healthy Human Lifespan

A recent online discussion panel revealed some valuable insights into the political aspects of increasing healthy human lifespans. Perhaps the most exciting part of the panel involves the idea that getting politicians to support longevity/aging therapeutics might not be as hard as people may think. Giving

Exercising Group

Benefits of Exercise Can Be Transferred via Plasmapheresis

Scientists have transferred the neuroprotective effects of exercise to sedentary mice via plasma transfusion and identified an obscure protein that might be responsible for the effect [1]. It’s in the blood The idea that young blood can rejuvenate old organisms is ancient. Kings and tyrants reportedly

Coughing

A Relationship Between Senescence and Respiratory Infections

A study published in Aging Cell has shown that senescent cells impact the way that CD4 T cells differentiate into types and that senolytics can restore this differentiation to a more youthful one. Not all T cells are the same CD4 T cells, often known as

Rejuvenation Roundup image

Rejuvenation Roundup December 2021

2021 has come to a close, but rejuvenation biotechnology is still just beginning. Let’s see what the field has accomplished in December. LEAF News Holiday Wishes from Lifespan.io: Lifespan.io president Keith Comito thanks the community of Lifespan.io for helping to bring an end to the diseases

Sleeping Old Man

A Link Between the Circadian Rhythm and Aging

A new study published in Aging has shown a relationship between the circadian clock and the changes in gene expression with age. Two complex systems and four distinct species This study begins with an introduction to two complicated topics. The first is the circadian rhythm, the

Gitcoin GR12 funding round for longevity.

Gitcoin GR12 Is a Win-Win for Aging Research

In recent years, the cryptocurrency community has become increasingly interested in the drive to increase healthy human lifespans. Gitcoin introduces longevity research into its funding rounds  Gitcoin recently held its 12th funding round, and the community has chosen to raise cryptocurrency donations for aging research. Gitcoin

Uterus

NMN Slows Ovarian Aging in Mice

Scientists have found that long-term supplementation with NMN, an NAD+ precursor, dramatically slows reproductive aging in mice by improving mitochondrial function and alleviating senescence [1]. Reproductive aging affects women relatively early in life, but like other types of aging, this one has been considered normal until

Vaccination

A Potential Vaccine for Senescent Cells

The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the importance they hold for the other researchers in the field. They may or may not be

Christmas Fireplace

Happy Holidays from Lifespan.io

Dear Friends, As we close out the year and continue the holiday season, I want to take this opportunity to thank you for being part of our community at Lifespan.io and helping to bring an end to the diseases of aging. 2021 has been another challenging

Old and Young Mice

Senolytics Improve Muscle Regeneration Only in Old Animals

A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration? While it may not be obvious from the way senescent cells are often discussed in longevity