Lifespan Research Institute

Category: News

Cancer cells

Building a Universal Immunotherapy for Cancer

Researchers publishing in Cell Reports Medicine have described a method of using off-the-shelf, allogeneic immune cells as cancer therapy. Overcoming the hurdles of allogeneic cells Allogeneic cells come from other

Gitcoin

Gitcoin Launches Crypto Funding Round for Longevity

Gitcoin is a platform dedicated to supporting the development of open-source Web3 software – decentralized architecture based upon blockchain technology – and the funding of  “public goods” projects that are

Fasting diet

Separating Fact from Fiction in Anti-Aging Diets

Dr. Matt Kaeberlein and colleagues recently published a review summarizing anti-aging diets as well as their misconceptions [1]. Caloric restriction, fasting-mimicking diets, and intermittent fasting While fasting diets have been

Rejuvenation Roundup November

Rejuvenation Roundup November 2021

While new variants of the ongoing COVID-19 pandemic make the headlines, heart disease and cancer remain the top causes of death, and the mortality rates of all three maladies rise

Running mouse

Mitochondrial Calcium Uptake and Sarcopenia

A team of researchers publishing in Cell Death & Disease has found that the age-related decline of mitochondrial calcium uptake family member 3 (MICU3), a regulator of mitochondrial function, is

Meditation

Meditation Practices To Combat Alzheimer’s Disease

A team of researchers, including Dr. Olga M Limecki of TU Dresden University, has published a review on the effect of mindfulness meditation and loving-kindness compassion meditation (LKCM) and proposed

Oxygen tank

Effects Of Hyperbaric Oxygen Therapy On Aged Skin

Recent experiments published in the latest issue of Aging associate hyperbaric oxygen therapy with improvements in several biomarkers of skin aging. Hyperbaric oxygen therapy (HBOT) In HBOT, patients are exposed

Cancer cells

Building a Universal Immunotherapy for Cancer

Researchers publishing in Cell Reports Medicine have described a method of using off-the-shelf, allogeneic immune cells as cancer therapy. Overcoming the hurdles of allogeneic cells Allogeneic cells come from other sources than the individual being treated. As recipients of organ donations know, if the immune system

Gitcoin

Gitcoin Launches Crypto Funding Round for Longevity

Gitcoin is a platform dedicated to supporting the development of open-source Web3 software – decentralized architecture based upon blockchain technology – and the funding of  “public goods” projects that are intended to benefit everyone. Of course, one such public good is the extension of healthy human

Backwards Clock

Alpha-Ketoglutarate Decreases Biological Age in Human Study

A commercially available alpha-ketoglutarate-based supplement has been shown to roll back biological age by 7 years on average in a retrospective human study [1]. Live slower, die later Though metformin and rapamycin are getting most of the attention in the longevity field today, alpha-ketoglutarate (AKG) has emerged

Blood Vessels Eye

Narrowed Neck Arteries Lead to Reduced Blood Flow in Eyes

Researchers publishing in GeroScience have found that carotid artery stenosis, a consequence of hypertension, is linked to a lack of blood flow in the eyes. A disease that restricts blood flow to the brain Carotid artery stenosis (CAS) is a dangerous condition that is strongly associated

Fasting diet

Separating Fact from Fiction in Anti-Aging Diets

Dr. Matt Kaeberlein and colleagues recently published a review summarizing anti-aging diets as well as their misconceptions [1]. Caloric restriction, fasting-mimicking diets, and intermittent fasting While fasting diets have been practiced for centuries, a recent re-emergence of this research has come to the anti-aging field. The

Bifidobacterium

Bifidobacterium Adolescentis Improves Lifespan in Animals

A new publication in Nature Aging has investigated the role of the gut bacteria Bifidobacterium adolescentis in aging and longevity. The aging gut microbiome The gut microbiome, previously thought to be relatively inconsequential, seems to play a greater role in our physiology with each published study.

Rejuvenation Roundup November

Rejuvenation Roundup November 2021

While new variants of the ongoing COVID-19 pandemic make the headlines, heart disease and cancer remain the top causes of death, and the mortality rates of all three maladies rise sharply with advanced age. Let’s see what steps we’ve taken against aging in November. LEAF News

Cognitive puzzle

Metformin Alleviates Cognitive Impairment in Long-Term Study

Scientists have confirmed yet another positive effect of metformin: its prolonged use by people with diabetes lowers the risk of cognitive impairment and cerebral small vessel disease [1]. A meta-drug? Metformin is one of the top candidate geroprotective (life-prolonging) drugs for several reasons. First, it has

Running mouse

Mitochondrial Calcium Uptake and Sarcopenia

A team of researchers publishing in Cell Death & Disease has found that the age-related decline of mitochondrial calcium uptake family member 3 (MICU3), a regulator of mitochondrial function, is associated with sarcopenia, the aging-associated loss of muscle. Why mitochondria control their calcium uptake The calcium

Jean Hebert at EARD2021

Dr. Jean Hébert on Brain Regeneration at EARD2021

At Ending Age-Related Diseases 2021, Elena Milova interviewed Dr. Jean Hébert on how the human brain can be restored to youthful function. Script Elena: Greetings to the participants of Ending Age-Related Diseases 2021. This conference brings together thought leaders and researchers working on rejuvenation biotechnology with

Dividing stem cells

Rapamycin Prevents Stem Cells from Growing Too Big

Researchers have found that hematopoietic stem cells lose function as they grow larger and that rapamycin can alleviate this effect [1]. When cells become obese When it comes to cells, size matters, with stem cells being on the smaller side [2]. Scientists have suspected for quite some

Death sentence

p21 Expression Is a Delayed Death Sentence for Cells

Researchers publishing in Science have found that the well-known biomarker p21 starts a fatal timer for mouse liver cells. Get better or die As the researchers demonstrate, the cyclin-dependent kinase inhibitor p21, which is encoded by the Cdkn1a gene, is associated with its own secretome: the

Meditation

Meditation Practices To Combat Alzheimer’s Disease

A team of researchers, including Dr. Olga M Limecki of TU Dresden University, has published a review on the effect of mindfulness meditation and loving-kindness compassion meditation (LKCM) and proposed a model to study it [1]. Mindfulness and compassion mediation defined One of our Science to

Oxygen tank

Effects Of Hyperbaric Oxygen Therapy On Aged Skin

Recent experiments published in the latest issue of Aging associate hyperbaric oxygen therapy with improvements in several biomarkers of skin aging. Hyperbaric oxygen therapy (HBOT) In HBOT, patients are exposed to higher concentrations and higher pressures of oxygen than what they experience in everyday air. Pressures

Martin Borch Jensen interview

Martin Borch Jensen: Cutting the Gordian Knot of Aging

Before founding Impetus Grants, a non-profit that aims to speed up longevity research by handing out money to scientists, minus the bureaucracy, Martin Borch Jensen did his doctorate in the Bohr lab at the NIA and his postdoc at the Buck Institute, and he received an