Category: News
A Potential Vaccine for Senescent Cells
December 23, 2021
The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the
Happy Holidays from Lifespan.io
December 23, 2021
Dear Friends, As we close out the year and continue the holiday season, I want to take this opportunity to thank you for being part of our community at Lifespan.io
Senolytics Improve Muscle Regeneration Only in Old Animals
December 22, 2021
A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration?
The Effects of Physical Activity on Frailty
December 21, 2021
A new study shows that even low levels of physical activity are very good for your muscles, bones, and joints, but exercising too much can potentially harm you [1]. The
Tina Woods on a Longevity Ecosystem at EARD2021
December 20, 2021
At Ending Age-Related Diseases 2021, Elena Milova of Lifespan.io interviewed Tina Woods on the development of a longevity ecosystem, the importance of language, and the social aspects of extending lifespans.
A Vaccine for High Cholesterol Works in Mice
December 20, 2021
Researchers publishing in Cell Reports Medicine have discovered that a vaccine targeting angiopoietin-like protein 3 (ANGPTL3) alleviates dyslipidemia and improves outcomes in obese mice. What is dyslipidemia? Dyslipidemia is marked
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What
NewLimit: A New Biotech Working on Epigenetic Aging
December 17, 2021
Two investors, including a co-founder of Coinbase, have announced a new biotech venture that aims to solve aging by studying its epigenetic aspects. New kid on the block Long gone
Old Serum Shown to Kill Brain Stem Cells
December 16, 2021
A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from
Plant-Based Diet Linked To Reduced Leaky Gut Syndrome
December 15, 2021
The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60
Epigenetic Clock Shows Association With Cardiovascular Aging
December 15, 2021
A new study published in Mechanisms of Ageing and Development has found correlations between cardiovascular aging and a measure of epigenetic age acceleration [1]. Can epigenetic clocks predict cardiovascular disease?
A Grape seed Extract Slows Aging In Mice
December 14, 2021
Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us
Olive Derivative Fights Epigenetic Kidney Aging
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this
Viagra Identified as a Candidate Drug for Alzheimer’s
December 10, 2021
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable
Chinese Licorice Plant Extract Restores Fat Stem Cells
December 9, 2021
Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous
A Potential Vaccine for Senescent Cells
December 23, 2021
The journal Nature has published a letter communication regarding a senolytic vaccination study [1]. These letters are typically research studies that the editor chooses to urgently publish due to the importance they hold for the other researchers in the field. They may or may not be
Happy Holidays from Lifespan.io
December 23, 2021
Dear Friends, As we close out the year and continue the holiday season, I want to take this opportunity to thank you for being part of our community at Lifespan.io and helping to bring an end to the diseases of aging. 2021 has been another challenging
Senolytics Improve Muscle Regeneration Only in Old Animals
December 22, 2021
A new publication in Aging Cell has found divergent results between the post-injury muscle regeneration of young and old mice treated with senolytics [1]. Senescent cells: Friend or foe for muscle regeneration? While it may not be obvious from the way senescent cells are often discussed in longevity
The Effects of Physical Activity on Frailty
December 21, 2021
A new study shows that even low levels of physical activity are very good for your muscles, bones, and joints, but exercising too much can potentially harm you [1]. The unholy trinity Sarcopenia, osteoporosis, and osteoarthritis are the trio of age-related diseases that affect, respectively, muscles,
Tina Woods on a Longevity Ecosystem at EARD2021
December 20, 2021
At Ending Age-Related Diseases 2021, Elena Milova of Lifespan.io interviewed Tina Woods on the development of a longevity ecosystem, the importance of language, and the social aspects of extending lifespans. Script Elena: Greetings to the participants of Ending Age-Related Diseases 2021. This conference brings together thought
A Vaccine for High Cholesterol Works in Mice
December 20, 2021
Researchers publishing in Cell Reports Medicine have discovered that a vaccine targeting angiopoietin-like protein 3 (ANGPTL3) alleviates dyslipidemia and improves outcomes in obese mice. What is dyslipidemia? Dyslipidemia is marked by having an excess of low-density lipoprotein (LDL) cholesterol, a lack of high-density lipoprotein (HDL) cholesterol,
What Is Quercetin? A Summary of Quercetin
December 20, 2021
Found in many fruits and vegetables, quercetin may have some potential in the context of aging. Here, we take a look at this natural antioxidant and popular dietary supplement. What is quercetin? Quercetin is a natural flavonoid, which makes it part of a large family of
NewLimit: A New Biotech Working on Epigenetic Aging
December 17, 2021
Two investors, including a co-founder of Coinbase, have announced a new biotech venture that aims to solve aging by studying its epigenetic aspects. New kid on the block Long gone are the times when longevity biotech companies were scarce and poorly funded. Today, barely a week
Old Serum Shown to Kill Brain Stem Cells
December 16, 2021
A study published in Aging and Disease has shown how exposure to old serum causes hippocampal progenitor cells (HPCs), which form new neurons, to die. Drawing and testing serum from living people To begin their study, the researchers examined a middle-aged to old (MATO) cohort ranging
Plant-Based Diet Linked To Reduced Leaky Gut Syndrome
December 15, 2021
The MaPLE trial in Italy investigated whether or not increasing fruits and vegetables decreases leaky gut syndrome [1]. Background This study examines increased intestinal permeability (leaky gut) in adults 60 years and older [1]. Age has been reported to be a risk factor for increased intestinal
Epigenetic Clock Shows Association With Cardiovascular Aging
December 15, 2021
A new study published in Mechanisms of Ageing and Development has found correlations between cardiovascular aging and a measure of epigenetic age acceleration [1]. Can epigenetic clocks predict cardiovascular disease? One way researchers test the validity and usefulness of epigenetic clocks is to compare their outputs
A Grape seed Extract Slows Aging In Mice
December 14, 2021
Studying grape seed extract, scientists have discovered a new senomorphic compound that enhances chemotherapy and prolongs lifespan and healthspan in mice [1]. Nature’s drugstore Many drugs have come to us from the world of plants, including promising geroprotective molecules such as resveratrol. However, identifying specific components
Olive Derivative Fights Epigenetic Kidney Aging
December 13, 2021
Researchers publishing in Aging Cell have discovered how and why oleuropein (OLP), a polyphenol derived from olives, ameliorates epigenetic kidney aging. Upregulation and downregulation Like nearly everything in biology, this specific part of kidney aging results from a chain of events. Here, the researchers show that
Viagra Identified as a Candidate Drug for Alzheimer’s
December 10, 2021
After sifting through 1,600 FDA-approved drugs, scientists have shown that Viagra is significantly correlated with lower Alzheimer’s disease risk [1]. Re-repurposing Viagra? Viagra (sildenafil) is one of the most recognizable drugs in the world. Yet, sildenafil’s hailed effect on erectile dysfunction was discovered serendipitously. Originally, sildenafil
Chinese Licorice Plant Extract Restores Fat Stem Cells
December 9, 2021
Researchers publishing in Aging have reported that licochalcone A (LA), a flavonoid that originates from Chinese licorice, restores human adipose-derived stem cells (hADSCs) in cell culture. Reported positive effects Previous research on Licochalcone A has discovered that it has anti-inflammatory and anti-tumor effects [1], reduces obesity