Category: News
Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Oliver Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using
Journal Club October 2021 – Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an
Energy Metabolism Decline Linked To Alzheimer’s
October 21, 2021
Researchers publishing in Aging have discovered that an energy metabolism compound is associated with a protein that suppresses amyloid beta in a mouse model of Alzheimer’s. The compounds involved The
Lack of Klotho Associated With All-Cause Mortality
October 20, 2021
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging Prediction of mortality
Scientists Propose a New Targeted Senolytic
October 19, 2021
A group of researchers has developed a delivery system that identifies senescent cells and injects them with a deadly compound. This offers a potential solution to the problem of targeted
NR Temporarily Improves Immune Function in Mice
October 18, 2021
A study published in the Nature journal Aging and Mechanisms of Disease has shown that supplementation with nicotinamide riboside (NR) substantially improves the immune systems of older mice due to
$70 Million Rejuvenome Initiative Launches
October 15, 2021
Recently, the Astera Institute has announced that it will be collaborating with the Buck Institute on its Rejuvenome project. The project is a focused research organization (FRO), a new model
Allele Associated With Alzheimer’s Improves Cognition
October 15, 2021
Scientists have demonstrated that “the Alzheimer’s allele” APOE e4 helps cognition earlier in life prior to the onset of the disease [1]. This might point at a possible reason for
A Path Towards Restoring Thymic Function
October 14, 2021
A study published in Cell Reports shows how the thymus is stimulated to repair itself when dying thymocytes are depleted, paving the way towards novel methods of thymic regeneration. Cycles
Dylan Livingston: Increasing Healthy Lifespan Is Bipartisan
October 14, 2021
Dylan Livingston is the founder and president of A4LI – the Alliance for Longevity Initiatives. This newly created organization aims to fill an important niche as a non-profit that would
The Genetic Basis of Telomere Length
October 13, 2021
A new study in Nature Genetics has further illuminated the genetic regulation of telomere length and what implications it may have for various diseases and longevity. Telomeres and aging in
NMN vs. NAD vs. NR With Dr. Brad Stanfield
October 13, 2021
In this interview with Steve Hill of Lifespan.io, Dr. Brad Stanfield discusses the various forms of niacin along with NAD+ boosters such as NR and NMN, and he touches upon
Escaping Stem Cells Exacerbate Age-Related Hair Loss
October 12, 2021
Scientists showed that hair loss happens partially as a result of stem cells escaping from hair follicles. They also shot a stunning time-lapse video of the process. The stem cell
The Link Between Brain Age and Blood Pressure
October 11, 2021
Researchers publishing in Frontiers in Aging Neuroscience have discovered that blood pressure is directly linked to brain aging. The BrainAGE clock For this analysis, the researchers chose BrainAGE, a well-known,
What is Rapamycin? A Summary of Rapamycin
October 8, 2021
We take a look at rapamycin and why some researchers think it could be useful in combating aging. What is rapamycin? Rapamycin is a macrolide, a class of antibiotic that
Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Oliver Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker“. Join us live on Facebook at 1 PM
Journal Club October 2021 – Targeted clearance of senescent cells
October 22, 2021
The next Journal Club will be on Tuesday 2nd November and Dr. Medvedik will be taking a look at a new paper called “Targeted clearance of senescent cells using an antibody-drug conjugate against a specific membrane marker“. Join us live on the call at 1 PM
Energy Metabolism Decline Linked To Alzheimer’s
October 21, 2021
Researchers publishing in Aging have discovered that an energy metabolism compound is associated with a protein that suppresses amyloid beta in a mouse model of Alzheimer’s. The compounds involved The researchers describe nicotinamide mononucleotide adenylyltransferase 2 (Nmnat2) as a key co-factor for energy metabolism. This compound
Lack of Klotho Associated With All-Cause Mortality
October 20, 2021
A recent study in The Journals of Gerontology, Series A has associated low klotho levels with mortality in Americans over the age of 40. Klotho and aging Prediction of mortality is a major interest of the aging field and the broader medical field. Epigenetic clocks, senescent
Scientists Propose a New Targeted Senolytic
October 19, 2021
A group of researchers has developed a delivery system that identifies senescent cells and injects them with a deadly compound. This offers a potential solution to the problem of targeted delivery of senolytics [1]. Cellular senescence has been implicated in numerous aging-related disorders, including fibrosis, diabetes,
NR Temporarily Improves Immune Function in Mice
October 18, 2021
A study published in the Nature journal Aging and Mechanisms of Disease has shown that supplementation with nicotinamide riboside (NR) substantially improves the immune systems of older mice due to its effects on stem cell fate. However, the benefits do not persist after NR is removed.
$70 Million Rejuvenome Initiative Launches
October 15, 2021
Recently, the Astera Institute has announced that it will be collaborating with the Buck Institute on its Rejuvenome project. The project is a focused research organization (FRO), a new model of organization that is laser-focused on a specific scientific challenge that cannot be solved by existing
Allele Associated With Alzheimer’s Improves Cognition
October 15, 2021
Scientists have demonstrated that “the Alzheimer’s allele” APOE e4 helps cognition earlier in life prior to the onset of the disease [1]. This might point at a possible reason for some aspects of aging. What makes us stronger kills us later The risk of developing Alzheimer’s,
A Path Towards Restoring Thymic Function
October 14, 2021
A study published in Cell Reports shows how the thymus is stimulated to repair itself when dying thymocytes are depleted, paving the way towards novel methods of thymic regeneration. Cycles of involution, not a steady decline The researchers cite previous research showing that the thymus, despite
Dylan Livingston: Increasing Healthy Lifespan Is Bipartisan
October 14, 2021
Dylan Livingston is the founder and president of A4LI – the Alliance for Longevity Initiatives. This newly created organization aims to fill an important niche as a non-profit that would educate American politicians on life extension and promote policy changes beneficial for our cause. How can
The Genetic Basis of Telomere Length
October 13, 2021
A new study in Nature Genetics has further illuminated the genetic regulation of telomere length and what implications it may have for various diseases and longevity. Telomeres and aging in humans At one time the hottest topic in aging, telomeres are the protective caps at the
NMN vs. NAD vs. NR With Dr. Brad Stanfield
October 13, 2021
In this interview with Steve Hill of Lifespan.io, Dr. Brad Stanfield discusses the various forms of niacin along with NAD+ boosters such as NR and NMN, and he touches upon supplements, rapamycin, and other facets of the longevity world. Brad is very active in the community
Escaping Stem Cells Exacerbate Age-Related Hair Loss
October 12, 2021
Scientists showed that hair loss happens partially as a result of stem cells escaping from hair follicles. They also shot a stunning time-lapse video of the process. The stem cell cycle Stem cells reside in “stem cell compartments” in various tissues. By differentiating into multiple types
The Link Between Brain Age and Blood Pressure
October 11, 2021
Researchers publishing in Frontiers in Aging Neuroscience have discovered that blood pressure is directly linked to brain aging. The BrainAGE clock For this analysis, the researchers chose BrainAGE, a well-known, machine learning-based biomarker that uses MRI imagery in order to determine age [1]. The researchers of
What is Rapamycin? A Summary of Rapamycin
October 8, 2021
We take a look at rapamycin and why some researchers think it could be useful in combating aging. What is rapamycin? Rapamycin is a macrolide, a class of antibiotic that includes erythromycin, roxithromycin, azithromycin, and clarithromycin. Rapamycin exhibits potent antitumor and immunosuppressive activity. Where is rapamycin