Lifespan Research Institute

Category: News

Interview with Marc P. Bernegger

The Rising Importance of Crypto in Aging Research

The cryptocurrency world is colliding with aging research and life extension and could change how research gets funded. The cryptocurrency community is getting behind healthy life extension The landscape of

Supplements

What is Arginine? A Summary of L-Arginine

Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid,

Elderly Person Coughing

Teasing Apart the Effects of Aging and COVID-19

Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of

Bad news

HDAC Inhibitors Linked to Cellular Senescence

A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone,

Blockchain looks set to play a key role in funding aging research.

PulseChain Airdrop Raises $20m for SENS

The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX,

Aging timeline

The Enormous Economic Benefits of Targeting Aging

Using Peter Pan, Wolverine, and a powerful economic model, a trio of prominent scientists argues that slowing aging can bring gargantuan economic benefits – an order of magnitude bigger than

Runner

NMN Enhances Aerobic Capacity in Amateur Runners

A clinical trial of endurance runners recently published in the Journal of the International Society of Sports Nutrition found nicotinamide mononucleotide (NMN) to increase several measures of aerobic capacity. Could

Fibrotic liver

Telomere Loss And The Development Of Fibrosis

A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts,

Fish Oil

A Model Using Four Fatty Acids Predicts Mortality

A study published in the American Journal of Clinical Nutrition has shown that a model built on the concentration of four fatty acids predicts mortality in older people at least as well as a model that uses smoking and diabetes. A long-term cohort study This study

What is Alpha-lipoic Acid? A Summary of ALA

Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an organosulfur (an organic compound that contains sulfur) derived from caprylic acid (also known as octanoic acid).

Interview with Marc P. Bernegger

The Rising Importance of Crypto in Aging Research

The cryptocurrency world is colliding with aging research and life extension and could change how research gets funded. The cryptocurrency community is getting behind healthy life extension The landscape of research funding and investment is changing, particularly with the influx of interest from the crypto community

Supplements

What is Arginine? A Summary of L-Arginine

Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid, a building block used to make proteins, that plays an important role in regulating blood flow.

Saunas can activate heat shock proteins and may be a potential way to improve health and potentially, longevity.

Saunas for a Personal Health and Longevity Strategy

There are a few reasons to consider including sauna use as part of your personal health and longevity strategy. What is a sauna? The word sauna comes from the Finnish language, and it means an earth or snow pit. While Finnish saunas today are typically log-walled,

Elderly Person Coughing

Teasing Apart the Effects of Aging and COVID-19

Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of the disease and may help explain why COVID-19 has a more severe effect on older people.

Glioblastoma

Senescent Cells, p65, and a Possible Treatment for Cancer

A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Old paradigms in cellular senescence Cellular senescence contributes to aging and age-related diseases, likely primarily through the

Mice playing

Enriched Environments Youthen the Brains of Mice

A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those of young mice [1]. What is an enriched environment? For mice, enriched environments (ENRs) are “large

Bad news

HDAC Inhibitors Linked to Cellular Senescence

A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone, anyway? In biology, a histone is a protein that binds to DNA in order to control

Blockchain looks set to play a key role in funding aging research.

PulseChain Airdrop Raises $20m for SENS

The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX, is about to launch a new cryptocurrency called PulseChain. As part of that launch, he has

Solving brain puzzle

Loss of Peptide Not Amyloid Plaques a New Alzheimer’s Target

A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid accumulation may be the consequence, not the cause Over 100 years ago, Alois Alzheimer originally identified

Invisibility

Engineering Cells to Avoid Immune Detection in Transplants

Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients’ immune response [1]. Help me help you Cellular therapies involve transplanting cells into a patient to replace the activity of malfunctioning or

Aging timeline

The Enormous Economic Benefits of Targeting Aging

Using Peter Pan, Wolverine, and a powerful economic model, a trio of prominent scientists argues that slowing aging can bring gargantuan economic benefits – an order of magnitude bigger than previously thought [1]. The marriage of economics and geroscience The paper, published in Nature Aging, looks

Runner

NMN Enhances Aerobic Capacity in Amateur Runners

A clinical trial of endurance runners recently published in the Journal of the International Society of Sports Nutrition found nicotinamide mononucleotide (NMN) to increase several measures of aerobic capacity. Could NMN and exercise be synergistic? NMN is a NAD+ precursor well known to longevity researchers for

Fibrotic liver

Telomere Loss And The Development Of Fibrosis

A new study published in Aging has shown a link between a reduction in telomerase reverse transcriptase (TERT), the gene that allows for telomere maintenance, and the development of myofibroblasts, cells that are a part of organ fibrosis. It also documents the link between telomere attrition