Category: News
George Church on Gene Therapies and Longevity
July 28, 2021
Professor of Genetics at Harvard Medical School and one of the most prominent geroscientists, George Church works on gene therapies that can potentially reverse age-related diseases. We had the opportunity
Memory Restored in Aged Mice by Modifying the Brain’s ECM
July 28, 2021
Molecular Psychiatry has recently published a report from the University of Cambridge detailing how the brain’s extracellular matrix (ECM) changes with age, negatively impacting memory, and how modifying the components
Defeating Aging With Aubrey de Grey and Michael Rae
July 27, 2021
We recently caught up with Dr. Aubrey de Grey and Michael Rae from SENS Research Foundation (SRF) about the landscape in the field. We asked them two simple questions, and
A Model Using Four Fatty Acids Predicts Mortality
July 26, 2021
A study published in the American Journal of Clinical Nutrition has shown that a model built on the concentration of four fatty acids predicts mortality in older people at least
What is Alpha-lipoic Acid? A Summary of ALA
July 24, 2021
Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an
The Rising Importance of Crypto in Aging Research
July 23, 2021
The cryptocurrency world is colliding with aging research and life extension and could change how research gets funded. The cryptocurrency community is getting behind healthy life extension The landscape of
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid,
Saunas for a Personal Health and Longevity Strategy
July 22, 2021
There are a few reasons to consider including sauna use as part of your personal health and longevity strategy. What is a sauna? The word sauna comes from the Finnish
Teasing Apart the Effects of Aging and COVID-19
July 22, 2021
Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of
Senescent Cells, p65, and a Possible Treatment for Cancer
July 21, 2021
A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Old
Enriched Environments Youthen the Brains of Mice
July 20, 2021
A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those
HDAC Inhibitors Linked to Cellular Senescence
July 19, 2021
A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone,
PulseChain Airdrop Raises $20m for SENS
July 17, 2021
The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX,
Loss of Peptide Not Amyloid Plaques a New Alzheimer’s Target
July 16, 2021
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid
Engineering Cells to Avoid Immune Detection in Transplants
July 15, 2021
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients’ immune response [1]. Help me help
George Church on Gene Therapies and Longevity
July 28, 2021
Professor of Genetics at Harvard Medical School and one of the most prominent geroscientists, George Church works on gene therapies that can potentially reverse age-related diseases. We had the opportunity to interview this prolific researcher and entrepreneur, who is involved in dozens of startups, on topics
Memory Restored in Aged Mice by Modifying the Brain’s ECM
July 28, 2021
Molecular Psychiatry has recently published a report from the University of Cambridge detailing how the brain’s extracellular matrix (ECM) changes with age, negatively impacting memory, and how modifying the components of the brain ECM can revitalize memory in mice [1]. What is neuroplasticity? Neuroplasticity is the
Defeating Aging With Aubrey de Grey and Michael Rae
July 27, 2021
We recently caught up with Dr. Aubrey de Grey and Michael Rae from SENS Research Foundation (SRF) about the landscape in the field. We asked them two simple questions, and they joined forces to give us their combined insights. Lifespan.io: First, do you think we can
A Model Using Four Fatty Acids Predicts Mortality
July 26, 2021
A study published in the American Journal of Clinical Nutrition has shown that a model built on the concentration of four fatty acids predicts mortality in older people at least as well as a model that uses smoking and diabetes. A long-term cohort study This study
What is Alpha-lipoic Acid? A Summary of ALA
July 24, 2021
Alpha-lipoic acid (also known as ALA) is a common supplement, and we take a look at it in the context of aging. What is alpha-lipoic acid? Alpha-lipoic acid is an organosulfur (an organic compound that contains sulfur) derived from caprylic acid (also known as octanoic acid).
The Rising Importance of Crypto in Aging Research
July 23, 2021
The cryptocurrency world is colliding with aging research and life extension and could change how research gets funded. The cryptocurrency community is getting behind healthy life extension The landscape of research funding and investment is changing, particularly with the influx of interest from the crypto community
What is Arginine? A Summary of L-Arginine
July 23, 2021
Arginine is a popular sports supplement, but could it also be useful in the context of healthy longevity? What is arginine? Arginine, also known as L-arginine, is an amino acid, a building block used to make proteins, that plays an important role in regulating blood flow.
Saunas for a Personal Health and Longevity Strategy
July 22, 2021
There are a few reasons to consider including sauna use as part of your personal health and longevity strategy. What is a sauna? The word sauna comes from the Finnish language, and it means an earth or snow pit. While Finnish saunas today are typically log-walled,
Teasing Apart the Effects of Aging and COVID-19
July 22, 2021
Researchers have used a big data approach to disentangle cellular and physiological changes that are specific to COVID-19 from those caused by aging [1]. Identifying these improves our understanding of the disease and may help explain why COVID-19 has a more severe effect on older people.
Senescent Cells, p65, and a Possible Treatment for Cancer
July 21, 2021
A report in the Journal of Cell Science has outlined different stages of cellular senescence alongside a mechanism that reverses it, along with a potential new treatment for glioblastoma. Old paradigms in cellular senescence Cellular senescence contributes to aging and age-related diseases, likely primarily through the
Enriched Environments Youthen the Brains of Mice
July 20, 2021
A study published in Nature Communications has shown that an environment rich in stimuli changes the epigenetics of the mouse hippocampus, making the brains of aged mice more like those of young mice [1]. What is an enriched environment? For mice, enriched environments (ENRs) are “large
HDAC Inhibitors Linked to Cellular Senescence
July 19, 2021
A study published in Aging has shown that inhibiting histone deacetylases (HDACs), an approach used for treating cancer and other diseases, can lead to cellular senescence. What is a histone, anyway? In biology, a histone is a protein that binds to DNA in order to control
PulseChain Airdrop Raises $20m for SENS
July 17, 2021
The SENS Research Foundation has apparently already raised four times its annual income thanks to the PulseChain Airdrop. The PulseChain airdrop supporting aging research Richard Heart, the founder of HEX, is about to launch a new cryptocurrency called PulseChain. As part of that launch, he has
Loss of Peptide Not Amyloid Plaques a New Alzheimer’s Target
July 16, 2021
A recent study, led by the University of Cincinnati in collaboration with the Karolinska Institute in Sweden, challenges the popular amyloid hypothesis that has dominated Alzheimer’s research for decades. Amyloid accumulation may be the consequence, not the cause Over 100 years ago, Alois Alzheimer originally identified
Engineering Cells to Avoid Immune Detection in Transplants
July 15, 2021
Gene editing can make stem cells invisible to the immune system, making it possible to carry out cell therapy transplants without suppressing the patients’ immune response [1]. Help me help you Cellular therapies involve transplanting cells into a patient to replace the activity of malfunctioning or