Lifespan Research Institute

Category: News

Dividing cells

Harnessing the Unaging Germline

A team of researchers, including Michael West of AgeX Therapeutics, has authored a review paper that posits a fundamental difference between “immortal” germline cells and “mortal” somatic cells. The two

Rejuvenation Roundup April

Rejuvenation Roundup April 2021

We’ve all aged another month, but we’re another month closer to discovering how to reverse it. Here’s what we’ve learned about aging in the month of April. LEAF News Promising

Elderly woman sleeping

Why Quality Sleep Should Be Part of Your Longevity Strategy

Quality sleep is one of the foundations of health, and a new study suggests that poor sleep quality is a major risk factor for developing Alzheimer’s disease and other dementias. Dementia is a rising global problem Worldwide, close to fifty million people currently live with Alzheimer’s

Ramadan is a time of fasting.

Intermittent Fasting During Ramadan Alters Gut Bacteria

Intermittent fasting changes the composition of the gut microbiome, according to new research [1]. An increase in the abundance of a group of bacteria known as Lachnospiraceae may explain some of the health benefits linked with dietary restriction. A natural experiment Intermittent fasting—the repeated, severe restriction

Spinal degradation

DHE Reduces Inflammation, Senescence in Intervertebral Discs

Recent research out of Frontiers in Pharmacology has shown that a natural herbal compound reduces senescence and intervertebral disc degeneration in mice. Cellular senescence in intervertebral disc degeneration Located between our vertebral bones, intervertebral discs are the shock-absorbing tissues that allow the spine to bend. Like

Some People think Life Extension is “Just a Fear of Death”

Sometimes those working in the field of rejuvenation biotechnology face the accusation that what they are doing is just a fear of death, like not being scared of age-related diseases is somehow brave. War used to be fashionable but now it isn’t These days, war is

Neurons

Gene Therapy Improves the Brains of Mice With Alzheimer’s

Scientists have successfully improved learning and memory, as well as neuronal morphology, in Alzheimer’s-prone mice with the help of a gene therapy that upregulates a vital protein [1]. Alzheimer’s disease (AD) has been a notoriously hard problem to crack, despite major R&D investment. AD has long

Dividing cells

Harnessing the Unaging Germline

A team of researchers, including Michael West of AgeX Therapeutics, has authored a review paper that posits a fundamental difference between “immortal” germline cells and “mortal” somatic cells. The two types of cells This review paper, which cites 175 other papers, goes back throughout history, discussing

Journal Club

Aging Begins After a Rejuvenation Event in Early Life

The Journal Club hosted by Dr. Oliver Medvedik returns for another episode on May 25th at noon Eastern / 5 UK time live on our Facebook page. This month, we have one of the authors, Dr. Vadim Gladyshev, joining us, and he will be talking us

Centenarian

People Living 105+ Years Appear to Repair DNA Better

A new study has shown that people who live for over 105 years typically have a genetic makeup that allows better repair of DNA damage [1]. Looking at the genomes of people who enjoy extreme longevity There has always been lots of interest in what allows

Bigmouth Buffalo Fish

No Sign of Aging in Long-Lived Bigmouth Buffalo Fish

Extremely long-lived bigmouth buffalo fish show no signs of a physiological decline with age, according to a new study. This clear example of negligible senescence in aging vertebrates demonstrates the need to better understand the mechanisms underlying senescence and points the way towards research that could

Kizoo logo

Kizoo Technology Pledges €300 Million to Rejuvenation

It is always good to report on positive news for a change, and today is one of those happy occasions. Michael Greve, founder of Forever Healthy and Kizoo, has commited €300 million (just over $360 million at the time of writing) to support the development of

Supplements

Developing a Science-based Personal Longevity Strategy

There is one common public reaction to my talks that bothers me quite a bit. I am worried that after each of my lectures, people will just start taking lots of supplements without regard for dosage or effectiveness, potentially hurting themselves in the process. This is

Young rat

Vibration Reduces Cellular Senescence in the Bones of Rats

A new study published in the journal Aging has examined the effects of vibration on cellular senescence and osteoporosis. Superior treatments are needed for osteoporosis Typically, bone density peaks for individuals around age 30 and then declines with age. While osteoporosis is rarely a direct cause

A long-eared, long-tailed mouse

Rapamycin Reduces Age-Related Hearing Loss in Mice

Researchers have found that rapamycin supplementation attenuates but not reverses age-related hearing loss in mice, even if the treatment starts later in life [1]. Hear ye, aging is coming Gradual hearing loss might not be as physically harmful as cancer, Alzheimer’s or many other age-related pathologies,

Eye

Phase 2 Trial Of Gene Therapy For Diabetic Macular Edema

Following a significant adverse event in which a patient lost vision in an eye treated with ADVM-022, Adverum Biotechnologies has unveiled the details of its Phase 2 trial of this gene therapy for diabetic macular edema. An overgrowth of blood vessels Wet age-related macular degeneration (AMD)

Rejuvenation Roundup April

Rejuvenation Roundup April 2021

We’ve all aged another month, but we’re another month closer to discovering how to reverse it. Here’s what we’ve learned about aging in the month of April. LEAF News Promising to connect biotech innovators and investors, researchers and policymakers, the Longevity Leaders World Congress will start