Category: Supplements
Study Suggests NMN May Improve NAD+ and Walking Speed
December 13, 2022
A new study suggests that NMN supplementation elevates NAD+ levels and increases walking distance in healthy participants, with 600 mg/day being the optimal dose [1]. NAD+ and its precursors While
FDA Purges NMN From the List of Supplements
November 16, 2022
Reversing its own earlier decision, the FDA has informed an NMN manufacturer that the molecule can no longer be marketed as part of dietary supplements. Another company that is testing
The Effects of Niacin on Alzheimer’s in Mice
November 14, 2022
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer’s and outlined the genes involved. Niacin’s known effects
Multivitamin Supplementation Shown to Improve Cognition
September 16, 2022
In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one
Vitamin D Fails to Improve Bone Health in Mega-Study
August 2, 2022
A high-quality, randomized, controlled trial found no effect of vitamin D supplementation or blood levels on the incidence of fractures in an aging population [1]. The common perception doesn’t match
Glutamine Supplementation Has Anti-Aging Potential
July 27, 2022
A new study published in Frontiers of Pharmacology has shown that glutamine deprivation might speed up aging while glutamine supplementation reduces oxidative stress-induced senescence in mice [1]. Glutamine is an
Blueberry Extract Reduces Aging Biomarkers in Rat Livers
July 25, 2022
A study published in Oxidative Medicine and Cellular Longevity has shown how blueberry extract moderately improves several age-related biomarkers in the livers of aging male rats. Rich in polyphenols In
Vitamin D Supplements May Make Alzheimer’s Worse
July 21, 2022
Researchers publishing in Aging Cell have found that administering Vitamin D to Alzheimer’s patients may actually make the problem worse. A matter of cause and effect Vitamin D deficiency is
Short-Term Resveratrol Reverses Ovarian Aging in Mice
July 12, 2022
Researchers have shown that resveratrol reverses several features of ovarian aging in mice while activating most sirtuins and boosting mitochondrial health [1]. Ovaries age first In many mammals, including humans,
Cocoa Extract Reduces Cardiovascular Mortality
June 28, 2022
A large-scale, randomized, controlled trial has found that in aging adults, cocoa extract does not affect the prevalence of adverse cardiovascular events but decreases their lethality [1]. Rich in flavanols
Vitamin D Supplements Linked to Slower Epigenetic Aging
June 13, 2022
Using a Berlin cohort, a study published in GeroScience has uncovered a link between Vitamin D supplementation and a reduction of epigenetic age. On the back of previous work This
Urolithin A Improves Muscle Strength in Middle-Aged Adults
June 10, 2022
A new study published in Cell Reports Medicine shows that urolithin A supplementation improves muscle strength, fitness, and mitochondrial health in overweight, middle-aged adults [1]. Mitophagy in aging and in
NMN Human Trial Results Published
June 2, 2022
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect
Study Suggests NMN May Improve NAD+ and Walking Speed
December 13, 2022
A new study suggests that NMN supplementation elevates NAD+ levels and increases walking distance in healthy participants, with 600 mg/day being the optimal dose [1]. NAD+ and its precursors While NAD+ can be supplemented via precursors such as NMN, this route has a few roadblocks as
FDA Purges NMN From the List of Supplements
November 16, 2022
Reversing its own earlier decision, the FDA has informed an NMN manufacturer that the molecule can no longer be marketed as part of dietary supplements. Another company that is testing NMN as a drug probably contributed to the decision, which is not being enforced as of
The Effects of Niacin on Alzheimer’s in Mice
November 14, 2022
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer’s and outlined the genes involved. Niacin’s known effects Niacin supplementation has been previously researched in its effects on neurological diseases: we have discussed its
Multivitamin Supplementation Shown to Improve Cognition
September 16, 2022
In a large randomized, placebo-controlled study, scientists hoped that cocoa extract would improve cognitive function in elderly patients, but instead it was a multivitamin supplement that shined [1]. A two-in-one study Multivitamins are among the most popular dietary supplements, but their effectiveness is often questioned. While
Vitamin D Fails to Improve Bone Health in Mega-Study
August 2, 2022
A high-quality, randomized, controlled trial found no effect of vitamin D supplementation or blood levels on the incidence of fractures in an aging population [1]. The common perception doesn’t match the science It’s a long-held aphorism that vitamin D is good for bone health. This has
Glutamine Supplementation Has Anti-Aging Potential
July 27, 2022
A new study published in Frontiers of Pharmacology has shown that glutamine deprivation might speed up aging while glutamine supplementation reduces oxidative stress-induced senescence in mice [1]. Glutamine is an amino acid of paramount importance for many cellular functions. It is involved in the synthesis of
Blueberry Extract Reduces Aging Biomarkers in Rat Livers
July 25, 2022
A study published in Oxidative Medicine and Cellular Longevity has shown how blueberry extract moderately improves several age-related biomarkers in the livers of aging male rats. Rich in polyphenols In their introduction, the researchers describe polyphenols, a broad category of plant compounds that includes flavonoids. Specifically,
Vitamin D Supplements May Make Alzheimer’s Worse
July 21, 2022
Researchers publishing in Aging Cell have found that administering Vitamin D to Alzheimer’s patients may actually make the problem worse. A matter of cause and effect Vitamin D deficiency is strongly linked to Alzheimer’s disease [1], and previous research has suggested that addressing this deficiency might
Short-Term Resveratrol Reverses Ovarian Aging in Mice
July 12, 2022
Researchers have shown that resveratrol reverses several features of ovarian aging in mice while activating most sirtuins and boosting mitochondrial health [1]. Ovaries age first In many mammals, including humans, ovarian aging is premature compared to other systems. The reasons for this accelerated loss of function
Cocoa Extract Reduces Cardiovascular Mortality
June 28, 2022
A large-scale, randomized, controlled trial has found that in aging adults, cocoa extract does not affect the prevalence of adverse cardiovascular events but decreases their lethality [1]. Rich in flavanols The nutrients that we consume obviously impact our healthspan and lifespan, but studying their effects in
Vitamin D Supplements Linked to Slower Epigenetic Aging
June 13, 2022
Using a Berlin cohort, a study published in GeroScience has uncovered a link between Vitamin D supplementation and a reduction of epigenetic age. On the back of previous work This study’s cohort consisted of 60- to 85-year-old participants in the Berlin Aging Study II (BASE-II). The
Urolithin A Improves Muscle Strength in Middle-Aged Adults
June 10, 2022
A new study published in Cell Reports Medicine shows that urolithin A supplementation improves muscle strength, fitness, and mitochondrial health in overweight, middle-aged adults [1]. Mitophagy in aging and in disease Mitochondrial dysfunction is one of the hallmarks of aging. It is associated with age-related skeletal
NMN Human Trial Results Published
June 2, 2022
The data from a multicenter NMN clinical trial have been published with some very modest but still interesting results [1]. What is NMN? NMN is short for nicotinamide mononucleotide, a naturally occurring molecule present in all species. It is a precursor of nicotinamide adenine dinucleotide (NAD+),
Vitamin D Dosing Safety in a Randomized, Controlled Trial
March 9, 2022
New data has been released from the Vitamin D Type 2 Diabetes (D2d) study [1]. This study is a randomized, controlled trial that includes overweight and obese people studied at 22 academic medical centers in the United States. This data was collected between October 2013 and
Urolithin A Affects Muscle and Mitochondria in Older Adults
February 23, 2022
A study published in the Journal of the American Medical Association has examined the dosage and safety of a urolithin A supplement [1]. This study also examined urolithin A‘s effect on muscle endurance and specific health biomarkers. A randomized, controlled clinical trial This study is a