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We Are Building a Future Free of Age-Related Disease

Lifespan  Research Institute is focused on strategically driving forward science to extend healthy human lifespan – through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

Age-related diseases such as Alzheimer’s, heart disease, and cancer,  cause untold harm –  both in terms of personal suffering and socio-economic effects. Like treating the trunk of a tree as opposed to its various branches, it is a much more effective strategy to treat age-related maladies by addressing the process that is at the heart of them all, the aging process itself.

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases. 

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease​

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

2.5 Years

3 Years

Cure Heart Disease

4 Years

5 Years

Improved Aging

25+ Years

Research Highlights -

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

Lifespan Research Institute is seeking volunteers for blood donations.

Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

Outreach Highlights -

At the A4LI DC Summit Event, Keith Comito moderated the panel  “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News

Public Longevity Group

Lifespan Research Institute Launches Public Longevity Group

[Mountain View, September 17, 2025] — Lifespan Research Institute (LRI) today announced the launch of the Public Longevity Group (PLG), a new initiative focused on bridging the cultural gap between scientific breakthroughs in aging and their public acceptance. To kickstart

Lifespan Alliance

Lifespan Alliance Launch & New Leadership at LRI

Mountain View, California — Lifespan Research Institute, a nonprofit leader in longevity science and advocacy, announces the launch of the Lifespan Alliance, a sponsorship initiative uniting mission-driven companies and visionary organizations dedicated to extending healthy human lifespan. Member organizations, including

T cells

Gamma Delta T Cells Show Promise Against Cellular Senescence

Scientists from the Lifespan Research Institute have discovered that a subset of T cells effectively targets senescent cells and improves outcomes in a mouse model of idiopathic pulmonary fibrosis [1]. How do we harness the immune system against senescence? Cellular