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Lifespan Alliance Launch & New Leadership at LRI

Mountain View, California — Lifespan Research Institute, a nonprofit leader in longevity science and advocacy, announces the launch of the Lifespan Alliance, a sponsorship initiative uniting mission-driven companies and visionary organizations dedicated to extending healthy human lifespan. Member organizations, including

Gamma Delta T Cells Show Promise Against Cellular Senescence

Scientists from the Lifespan Research Institute have discovered that a subset of T cells effectively targets senescent cells and improves outcomes in a mouse model of idiopathic pulmonary fibrosis [1]. How do we harness the immune system against senescence? Cellular

Using a Surface Biomarker to Target Senescent Cells

Scientists have identified a senescence-associated surface protein that can be targeted using antibodies [1]. This discovery might help distinguish between beneficial and harmful senescent cells and could speed up the development of senolytic therapies. This work was done by the Lifespan

Creating a World Where Everyone Can Live Longer, Healthier Lives

Bringing You The Latest News In the Field of Aging Research

We Are Building a Future Free of Age-Related Disease

Lifespan Research Institute is focused on strategically driving forward science to extend healthy human lifespan – through advocacy, ecosystem building, and direct support of cutting edge research into the root causes of aging.

Our Research

We conduct targeted scientific research with the explicit goal of accelerating the development of therapies that address the root causes of aging.

Education Opportunities

Our educational programs offer several options for students interested in engaging with our mission of preventing age-related diseases.

Longevity Investor Network

Through our investor network, we catalyze private investment in biotechnology companies developing interventions that target the root mechanisms of aging.

Public Advocacy

We make the ground fertile for the entire field through advocacy initiatives that foster societal change, increasing available public and private funding for aging research.

Addressing the Root Causes of Aging is a Much Better Way to Fight Disease

Healthy Life Expectancy and Total Life Expectancy Gained

Cure Cancer

Cure Heart Disease

Improved Aging

Research Highlights -

New Paper from LRI's Sharma Lab on Novel Senescent Cell Targeting

This study identifies an aberrant localization of the protein LAMP1 on the surface of senescent cells. Cells that presented LAMP1 on the surface showed clear signs of having a senescent/aged phenotype. The team was able to target LAMP1 on the surface of senescent cells to eliminate them.

LRI Needs Volunteers for Aging and Longevity Study.

Lifespan Research Institute is seeking volunteers for blood donations.

Your participation will help advance our understanding of the immune system and mitochondrial biology in aging.

Outreach Highlights -

Keith Comito Moderates Panel on the Geopolitics of Aging Research at the A4LI DC Summit

At the A4LI DC Summit Event, Keith Comito moderated the panel “Aging Populations: A Geopolitical Perspective” with Niklas Anzinger, Mac Davis, and Jasmine Smith, exploring how global demographic shifts toward aging populations impact societies, economies, and international cooperation.

Latest LRI News