Lifespan Research Institute

Category: News

Human ear anatomy

A Potential Gene Therapy for Hearing Loss

In JCI Insight, researchers have explored the possibility of using gene therapy to restore a crucial protein and repair hearing loss. Hearing and its failure In mammals, afferent neurons, which

A computer generated image of stem cells

Keeping Stem Cells Healthy and Young

A team of researchers has outlined a new approach that uses mRNA to prevent senescence and strengthen mesenchymal stem cells (MSCs) against aging before they are transplanted into patients. Stem

Rejuvenation Roundup December 2024

Rejuvenation Roundup December 2024

The holiday season is over and the new year is here, and we’re back to discussing the one gift that matters the most: biological rejuvenation. Let’s see what’s been done

Longevity Summit 2024 Panel

The Best Talks From Longevity Summit 2024

Earlier this month, for the third year in a row, the famed Buck Institute for Research on Aging hosted the Longevity Summit. This two-day event was organized by Longevity Global,

Master rower

Lower Rates of Epigenetic Aging in Olympic Champions

A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to

Surgical incision

A Senolytic Approach to Faster Wound Healing

Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While

Alopecia

Encouraging Hair Growth by Reducing Senescence

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair

Long Game

LongGame Venture Capital Fund Officially Launched

Crypto investor and founder Will Harborne will lead a new enterprise aimed at funding and supporting groundbreaking longevity technologies. From crypto to longevity The burgeoning field of longevity biotech is

Cynomolgus monkey

Extending Monkeys’ Reproductive Span With Stem Cells

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction

Bladder

Senescent Cells Protect the Bladder

In Aging Cell, a research team has explained why barrier cells in the human bladder are largely senescent and what might lead them to become cancerous. Targeting the right cells

Caloric restriction

Receiving Caloric Restriction Benefits Without Practicing It

In a new study, researchers have found that lithocholic acid, a metabolite found in the serum of calorically restricted mice, can mimic the effects of caloric restriction [1]. Restricting calories to live longer Caloric restriction without malnutrition improves healthspan and extended lifespan in multiple model organisms

Liver cancer

Drinking and Dying: Alcohol as a Risk Factor for Cancer

A new advisory by the US Surgeon General highlights a topic that – as the document itself notes – has been flying mostly under the public’s radar: the relationship between alcohol consumption and cancer. While most people are aware of smoking and obesity being risk factors

Human ear anatomy

A Potential Gene Therapy for Hearing Loss

In JCI Insight, researchers have explored the possibility of using gene therapy to restore a crucial protein and repair hearing loss. Hearing and its failure In mammals, afferent neurons, which originate from the inner ear, transform received stimuli (sound waves) into electrical signals [1]. This process

A computer generated image of stem cells

Keeping Stem Cells Healthy and Young

A team of researchers has outlined a new approach that uses mRNA to prevent senescence and strengthen mesenchymal stem cells (MSCs) against aging before they are transplanted into patients. Stem cells go bad before they can be used The researchers introduce this study by focusing on

Rejuvenation Roundup December 2024

Rejuvenation Roundup December 2024

The holiday season is over and the new year is here, and we’re back to discussing the one gift that matters the most: biological rejuvenation. Let’s see what’s been done in December. LEAF News Another Year of Longevity Advocacy and Journalism: The nights are the longest

Editorial

Another Year of Longevity Advocacy and Journalism

The nights are the longest of the year, the holidays are drawing near, and we are back with a festive edition of the Lifespan.io editorial. This time, we bring you some of this year’s highlights and talk about what the future holds for our content. Lifespan.io

Longevity Summit 2024 Panel

The Best Talks From Longevity Summit 2024

Earlier this month, for the third year in a row, the famed Buck Institute for Research on Aging hosted the Longevity Summit. This two-day event was organized by Longevity Global, a community of longevity researchers, investors, and enthusiasts, and its founder Dr. Christin Glorioso. While not

Encapsulated DNA

How Cellular Reprogramming Affects Mitochondrial Dysfunction

Creating induced pluripotent stem cells (iPSCs) causes mutant mitochondrial populations to change, and researchers have investigated this phenomenon more thoroughly. Easy to mutate Being outside of the protection of the nucleus, mitochondria DNA (mtDNA) mutates at anywhere from 10 to 100 times the rate of nuclear

Master rower

Lower Rates of Epigenetic Aging in Olympic Champions

A recent investigation into Hungarian Olympic champions suggests slower epigenetic aging and differences in gene methylation patterns between champions and non-champions [1]. Exercising your way to longevity Exercise seems to be the best lifestyle factor to slow aging and alleviates many aging-associated diseases and molecular changes.

Surgical incision

A Senolytic Approach to Faster Wound Healing

Researchers have published in Aging their findings that a senolytic compound accelerates wound healing in aged mice when it is administered before the wound occurs. A well-known laboratory senolytic While some senescent cells have been found to have a beneficial effect on wound healing [1], the

Alopecia

Encouraging Hair Growth by Reducing Senescence

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair treatment There has been a substantial amount of previous work in restoring hair follicle growth by

Jamie Justice XPRIZE

Why Research Teams Should Email XPRIZE Healthspan Now

With the deadline for submissions just around the corner, Jamie Justice, Executive Director of XPRIZE HealthSpan, explains to researchers still on the fence why they should contact her team now but also why missing the deadline is not the end of the world. XPRIZE Foundation has

Long Game

LongGame Venture Capital Fund Officially Launched

Crypto investor and founder Will Harborne will lead a new enterprise aimed at funding and supporting groundbreaking longevity technologies. From crypto to longevity The burgeoning field of longevity biotech is about to have a new player. Like many recent enterprises, such as Brian Armstrong’s NewLimit, this

Cynomolgus monkey

Extending Monkeys’ Reproductive Span With Stem Cells

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction in senescence-associated processes, such as inflammation, fibrosis, oxidative damage, and apoptosis [1]. Increasing healthspan by delaying

Bladder

Senescent Cells Protect the Bladder

In Aging Cell, a research team has explained why barrier cells in the human bladder are largely senescent and what might lead them to become cancerous. Targeting the right cells It is well-known that people develop urinary problems with advanced age, including increasing frequency and incontinence