Lifespan Research Institute

Category: News

Alopecia

Encouraging Hair Growth by Reducing Senescence

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair

Long Game

LongGame Venture Capital Fund Officially Launched

Crypto investor and founder Will Harborne will lead a new enterprise aimed at funding and supporting groundbreaking longevity technologies. From crypto to longevity The burgeoning field of longevity biotech is

Cynomolgus monkey

Extending Monkeys’ Reproductive Span With Stem Cells

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction

Bladder

Senescent Cells Protect the Bladder

In Aging Cell, a research team has explained why barrier cells in the human bladder are largely senescent and what might lead them to become cancerous. Targeting the right cells

Gene editing

Nuclear Expression of a Mitochondrial Gene in Mice

Scientists from the Longevity Research Institute (LRI), which was formed by the merger of SENS Research Foundation and Lifespan.io, have achieved expression of an essential mitochondrial gene in the nucleus

Skeletal muscle

Fragmented Mitochondria Linked to Muscle Weakness

In a study published in Aging Cell, researchers have outlined a relationship between mitochondrial fragmentation in skeletal muscle and the loss of strength with age. Broken power plants As its

Computer healthcare analysis

Can AI Predict Your Death?

Once confined to the realms of science fiction or relatively crude internet death calculators, AI-driven predictions about longevity are inching closer to reality. Questions about the accuracy and value of

Rejuvenation Roundup November 2024

Rejuvenation Roundup November 2024

While the United States has just celebrated a holiday that opposes caloric restriction, researchers there and around the world continue to discover the effects of it and other interventions against

Menopause

Building an Atlas of Human Ovarian Aging

The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function

Alopecia

Encouraging Hair Growth by Reducing Senescence

In Aging Cell, researchers have described how to improve the hair growth potential of stem cells and organoids by reducing cellular senescence. The quest for a true stem cell hair treatment There has been a substantial amount of previous work in restoring hair follicle growth by

Jamie Justice XPRIZE

Why Research Teams Should Email XPRIZE Healthspan Now

With the deadline for submissions just around the corner, Jamie Justice, Executive Director of XPRIZE HealthSpan, explains to researchers still on the fence why they should contact her team now but also why missing the deadline is not the end of the world. XPRIZE Foundation has

Long Game

LongGame Venture Capital Fund Officially Launched

Crypto investor and founder Will Harborne will lead a new enterprise aimed at funding and supporting groundbreaking longevity technologies. From crypto to longevity The burgeoning field of longevity biotech is about to have a new player. Like many recent enterprises, such as Brian Armstrong’s NewLimit, this

Cynomolgus monkey

Extending Monkeys’ Reproductive Span With Stem Cells

An investigation into transplanting human embryonic stem cells (hESC)-derived MSC-like cells (M cells) into the ovaries of cynomolgus monkeys suggests an extension of female reproductive span accompanied by a reduction in senescence-associated processes, such as inflammation, fibrosis, oxidative damage, and apoptosis [1]. Increasing healthspan by delaying

Bladder

Senescent Cells Protect the Bladder

In Aging Cell, a research team has explained why barrier cells in the human bladder are largely senescent and what might lead them to become cancerous. Targeting the right cells It is well-known that people develop urinary problems with advanced age, including increasing frequency and incontinence

Vitalism

Announcing Vitalist Bay, a Pop-Up City in the Bay Area

A unique project is set to go live next spring in the Bay Area. Organized by the Vitalism Foundation, it promises to be one of the largest longevity-related events ever. They’re popping up! Since the pop-up city of Zuzalu took the longevity community by storm in

Gene editing

Nuclear Expression of a Mitochondrial Gene in Mice

Scientists from the Longevity Research Institute (LRI), which was formed by the merger of SENS Research Foundation and Lifespan.io, have achieved expression of an essential mitochondrial gene in the nucleus and proper functioning of the protein. This could pave the way for curing diseases caused by

Skeletal muscle

Fragmented Mitochondria Linked to Muscle Weakness

In a study published in Aging Cell, researchers have outlined a relationship between mitochondrial fragmentation in skeletal muscle and the loss of strength with age. Broken power plants As its authors point out, this is far from the first study to link mitochondrial dysfunction and aging

Robot doctor

AI Outperforms AI-Assisted Doctors in Diagnostic Reasoning

In a new study, ChatGPT 4.0 achieved significantly better diagnostic scores when evaluating complex cases than either unassisted human physicians or physicians who consulted the chatbot [1]. Bad news for human doctors? For millions of people, chatbots powered by large language models (LLMs) have quickly become

Computer healthcare analysis

Can AI Predict Your Death?

Once confined to the realms of science fiction or relatively crude internet death calculators, AI-driven predictions about longevity are inching closer to reality. Questions about the accuracy and value of these forecasts remain. In recent years, researchers and companies around the globe have been pursuing answers

Oranges and Grapes

Resveratrol, Vitamin C Drop Oxidative Stress After Menopause

In a randomized, controlled trial published in Nutrients, researchers tested supplementation with resveratrol, vitamin C, and a combination of both. They learned that all of the treatments had a similar positive impact on oxidative stress in postmenopausal women [1]. Menopausal transition Around the world, a significant

Mehmood Khan Interview

Mehmood Khan on Aging Policy and Collaboration

I first met Dr. Mehmood Khan in 2022 at the inaugural Longevity Summit Dublin, where organizers Aubrey de Grey and Martin O’Dea made a bold decision to include policy and advocacy discussions alongside the traditional focus on longevity research. Like many others in the audience, I

Three supplements

A Clinical Trial of a Three-Part Treatment for Inflammaging

Reseachers publishing in Antioxidants have combined three antioxidant and anti-inflammatory compounds and tested their effects in human beings. Three complementing choices The first component the researchers included was AM3, a compound that is core to the Inmunoferon supplement and is an immunomodulator that has been found

Rejuvenation Roundup November 2024

Rejuvenation Roundup November 2024

While the United States has just celebrated a holiday that opposes caloric restriction, researchers there and around the world continue to discover the effects of it and other interventions against aging. Let’s see what’s been done in November. Interviews Rozalyn Anderson Explains Caloric Restriction: At the

Menopause

Building an Atlas of Human Ovarian Aging

The researchers of a Nature Aging paper used multi-omics approaches to investigate cellular, molecular, and genetic drivers of human ovarian aging [1]. An early decline A decline in ovarian function occurs before a similar decline in other organs. Already in their mid-to-late thirties, women can experience