Lifespan Research Institute

Category: News

Tricky balance

Fighting Inflammation May Cause More Senescence

A researcher publishing in Biogerontology has reviewed the literature on the relationship between cellular senescence and the immune system, finding that dwindling immune surveillance allows senescent cells to accumulate. The

Black 6 looking at viewer

NMN Increases Lifespan in Female Mice

A new preprint from David Sinclair’s lab has discovered that NMN supplementation started in midlife increases median and maximal lifespan in female mice and boosts healthspan in males [1]. NAD

Longevity Desci Recap July 2024

Longevity and DeSci Recap – July 2024

The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related

Rejuvenation Roundup July 2024

Rejuvenation Roundup July 2024

Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech

Tricky balance

Fighting Inflammation May Cause More Senescence

A researcher publishing in Biogerontology has reviewed the literature on the relationship between cellular senescence and the immune system, finding that dwindling immune surveillance allows senescent cells to accumulate. The immune system needs to be deadly On the cellular level, the bodies of vertebrates are brutal

Elderly eating healthy food

Anti-Inflammatory Diets Mitigate Risk of Dementia

A new study suggests that an anti-inflammatory diet can significantly reduce the risk of dementia and delay its onset even in people with existing cardiometabolic diseases [1]. Is it too late to lower the risk? Cardiometabolic diseases, such as type 2 diabetes, heart attack, and stroke,

Elderly man with large waistline

Inflammation May Drive Fat Distribution in Older People

A new study published in Aging Cell has detailed what happens to individual fat cells in white adipose tissue (WAT) as they age. When fat is more than just fat Previous research has described WAT as an organ in its own right, functioning not only as

Photo by Dinkum from Wikimedia Commons

A Botanical Extract Extends Lifespan and Healthspan in Mice

According to a new study, a polyphenol-rich natural extract positively impacts lifespan, healthspan, and cellular senescence. These results were observed in both cell culture and a mouse model [1]. From folk medicine to modern science Traditional and folk medicines offer many botanical extracts that can be

Black 6 looking at viewer

NMN Increases Lifespan in Female Mice

A new preprint from David Sinclair’s lab has discovered that NMN supplementation started in midlife increases median and maximal lifespan in female mice and boosts healthspan in males [1]. NAD and aging Nicotinamide adenine dinucleotide (NAD) is a ubiquitous metabolite that performs several crucial roles. NAD’s

Knee arthritis

A Ketosis-Related Compound Alleviates Arthritis in Rats

In Aging Cell, researchers have published details on the pathway by which a compound commonly found in ketone bodies ameliorates osteoarthritis in a rat model. Chondrocytes are crucial in arthritis The cartilage holding joints together is built and maintained by chondrocytes, which synthesize such necessary proteins

Michael Antonov Interview

Michael Antonov: from Oculus to Longevity Biotech

After Oculus was sold to Facebook for two billion dollars a decade ago, Michael Antonov, one of the founders, could have become a major tech investor, a popular podcaster with his own mega-theory of everything, a hedonist, or all of the above. Instead, he gravitated towards

Flowing blood with white blood cells

Immune Peptide Might Keep White Blood Cells Contained

In npj Aging, researchers have described how immune cell infiltration in inflammaging can be reduced with an immune-related peptide in a mouse model. Immune cell infiltration In a previous paper, these researchers have reported that aging affects the movement of white blood cells (leukocytes) in a

Intestines and blood vessels

Fecal Microbiota Transplants Reduce Vascular Aging in Mice

Fecal microbiota transplantation from young mice to older mice improved multiple metabolic parameters and some hallmarks of aging, such as inflammation and telomere shortening [1]. Bringing back the balance Dysbiosis, an imbalance in the gut microbiome, is a newly recognized hallmark of aging [2]. Dysbiosis elevates

HBO chamber

Hyperbaric Oxygen Therapy Increases Fitness in Elderly

In a new study, a 12-week protocol of hyperbaric oxygen therapy (HBOT) resulted in marked increases in aerobic capacity and cardiac blood flow [1]. Building pressure HBOT involves placing patients in a tightly sealed chamber where they breathe pure oxygen under higher-than-normal atmospheric pressure. This treatment

Hidden minefield

New Epigenetic Clock Built on Lurking DNA Fragments

In Aging Cell, a team of researchers has announced Retroelement-Age, a novel clock that focuses on the expression of buried pieces of DNA that are normally suppressed. Corrupted but unexpressed The natural human genome has a large number of artifacts left over from ancient viral infections

Longevity Desci Recap July 2024

Longevity and DeSci Recap – July 2024

The Longevity and DeSci Recap is back, and our latest edition covers high-profile events including the Longevity Investors Conference in Gstaad, new innovations in AFib monitoring, and even some celebrity-related news. This month, we’ll continue to explore the latest events, current research, and investment news to

Vegan foods

Vegan Diet Lowers Biological Age in a New Study

In a study that involved pairs of identical twins, Stanford scientists have shown that a healthy vegan diet leads to a decrease in biological age and possibly to other health benefits [1]. Do you really live longer if you eat well? A good diet can do

Black lab mice

Rapamycin + Trametinib Increase Mouse Lifespan by up to 35%

Combining rapamycin and trametinib seemed to have a cumulative effect in both sexes but mostly in females [1]. These results are probably due to a reduction in both cancer and inflammation. A winning combo The idea that combination treatments are the future of life extension is

Rejuvenation Roundup July 2024

Rejuvenation Roundup July 2024

Entirely new approaches with surprisingly good results have been recently discovered and published in July’s papers. Here’s what the research world has revealed this month. LEAF News Interviews Longevity Biotech Fellowship: Road To A Post-Aging Society: The Longevity Biotech Fellowship is one of the most interesting