Category: News
Study Suggests Mammals’ Lifespan Is Limited by Epigenetics
September 30, 2024
Juan José Alba-Linares and his research team have published a preprint study that examined why different animals age at different rates. They found that epigenetic changes over time could explain
A Bank of Centenarian Stem Cells
September 29, 2024
Researchers are keeping a bank of induced pluripotent stem cells (iPSCs) derived from centenarians and their descendants. They describe the purpose of this bank and its uses in Aging Cell.
Reprogramming Senescent Cells Extends Lifespan in Mice
September 27, 2024
Dr. Belmonte’s group at Altos Labs targeted stressed and senescent cells with partial reprogramming, producing large increases in lifespan in male mice [1]. What are they doing there? Since the
A Likely Beneficial Compound Also Predicts Mortality
September 26, 2024
Researchers publishing in Aging have found that fibroblast growth factor 21 (FGF21), an apparently beneficial protein naturally produced by the human body, heralds a greater likelihood of death. Multiple documented
Metformin Slows Aging in Non-Human Primates
September 26, 2024
In a new study, metformin, which has already shown good results in rodents and in human epidemiological studies, alleviated multiple signs of aging in male cynomolgus monkeys [1]. Now in
MSC Treatment Improves Age-Related Phenotypes in Rats
September 25, 2024
In a recent study, researchers injected rats with mesenchymal stromal cells. They observed improvements in aging-related biomarkers and phenotypes in many organs [1]. The rejuvenating role of MSCs Mesenchymal stromal
The Greenland Shark’s Genome Reveals Clues to Its Longevity
September 24, 2024
Scientists have compiled the most complete genome ever of the Greenland shark, an exceptionally long-lived species. Living up to 400 years probably has a lot to do with superior DNA
Axolotls’ Epigenetic Clocks Stop Ticking
September 23, 2024
In a preprint published in bioRxiv, researchers have published their findings in applying an epigenetic clock to the axolotl, a salamander species that does not age like humans. More than
For the 11th Year in Copenhagen: Highlights from ARDD 2024
September 20, 2024
The Copenhagen-based Aging Research and Drug Discovery Meeting (ARDD) was already enormous. Last year, there were well over a thousand physical participants, and many more online, attending five days of
The Ventricles of the Heart Age Differently
September 19, 2024
In Aging Cell, researchers have published their findings on how the right ventricle of the heart ages differently from the left one. Not just organs, but parts of organs Research
Combining Treatments Against Multiple Hallmarks of Aging
September 18, 2024
Researchers have published a review of the current state of combination therapies that address multiple Hallmarks of Aging [1]. Some of these combined therapies were found to induce greater lifespan
Light Pollution Linked to Alzheimer’s Disease Prevalence
September 17, 2024
Scientists have found a correlation between the intensity of nighttime outdoor lighting, which can disrupt sleep, and Alzheimer’s disease [1]. Light pollution – heavy consequences Outdoor lights help us with
Extracellular Vesicles to Fight Liver Fibrosis
September 16, 2024
Researchers have filled extracellular vesicles (EVs) with micro-RNA that is effective against liver fibrosis in mice and published their breakthrough in Aging Cell. The cellular postal service EVs, which cells
Less Talk, More Work: Foresight/LBF Longevity Workshop 2024
September 13, 2024
When Foresight Institute and Longevity Biotech Fellowship joined forces, a one-of-a-kind longevity event emerged. Something different There’s a time-tested recipe for a scientific conference: people come on stage one by
A New Atlas for Cellular Rejuvenation
September 12, 2024
In Aging, researchers from Spain and Luxembourg have described the creation of Single-cell RNA-seq Investigation of Rejuvenation Agents and Longevity (SINGULAR), an atlas for cellular rejuvenation that describes how interventions
Study Suggests Mammals’ Lifespan Is Limited by Epigenetics
September 30, 2024
Juan José Alba-Linares and his research team have published a preprint study that examined why different animals age at different rates. They found that epigenetic changes over time could explain why some animals live longer and estimated an upper limit for mammalian lifespan [1]. A problem
A Bank of Centenarian Stem Cells
September 29, 2024
Researchers are keeping a bank of induced pluripotent stem cells (iPSCs) derived from centenarians and their descendants. They describe the purpose of this bank and its uses in Aging Cell. A category of their own Centenarians don’t merely live for a hundred years; they spend more
Reprogramming Senescent Cells Extends Lifespan in Mice
September 27, 2024
Dr. Belmonte’s group at Altos Labs targeted stressed and senescent cells with partial reprogramming, producing large increases in lifespan in male mice [1]. What are they doing there? Since the discovery of cellular reprogramming almost two decades ago, a lot of hopes have been put into
A Likely Beneficial Compound Also Predicts Mortality
September 26, 2024
Researchers publishing in Aging have found that fibroblast growth factor 21 (FGF21), an apparently beneficial protein naturally produced by the human body, heralds a greater likelihood of death. Multiple documented benefits FGF21 plays crucial roles in the human body. Secreted by the liver and many other
Metformin Slows Aging in Non-Human Primates
September 26, 2024
In a new study, metformin, which has already shown good results in rodents and in human epidemiological studies, alleviated multiple signs of aging in male cynomolgus monkeys [1]. Now in monkeys Metformin, a well-established anti-diabetes drug, has been touted as a possible geroprotector since a study
MSC Treatment Improves Age-Related Phenotypes in Rats
September 25, 2024
In a recent study, researchers injected rats with mesenchymal stromal cells. They observed improvements in aging-related biomarkers and phenotypes in many organs [1]. The rejuvenating role of MSCs Mesenchymal stromal cells (MSCs) can be obtained from diverse sources, including bone marrow, adipose tissue, perinatal tissue, and
The Greenland Shark’s Genome Reveals Clues to Its Longevity
September 24, 2024
Scientists have compiled the most complete genome ever of the Greenland shark, an exceptionally long-lived species. Living up to 400 years probably has a lot to do with superior DNA repair mechanisms. Methuselahs of the sea Greenland sharks, giant, slow-moving abyss dwellers, hold the title of
Axolotls’ Epigenetic Clocks Stop Ticking
September 23, 2024
In a preprint published in bioRxiv, researchers have published their findings in applying an epigenetic clock to the axolotl, a salamander species that does not age like humans. More than just regeneration Axolotls, and salamanders more generally, are well-known for their regenerative capabilities, being able to
For the 11th Year in Copenhagen: Highlights from ARDD 2024
September 20, 2024
The Copenhagen-based Aging Research and Drug Discovery Meeting (ARDD) was already enormous. Last year, there were well over a thousand physical participants, and many more online, attending five days of wall-to-wall talks: more than a hundred in total. We called it “the mother of all longevity
The Ventricles of the Heart Age Differently
September 19, 2024
In Aging Cell, researchers have published their findings on how the right ventricle of the heart ages differently from the left one. Not just organs, but parts of organs Research on aging has agreed that organs age differently: that the arteries, brain tissue, muscles, and skin,
Combining Treatments Against Multiple Hallmarks of Aging
September 18, 2024
Researchers have published a review of the current state of combination therapies that address multiple Hallmarks of Aging [1]. Some of these combined therapies were found to induce greater lifespan extension than single treatments. A complex phenomenon calls for complex treatments The complexity of aging cannot
Light Pollution Linked to Alzheimer’s Disease Prevalence
September 17, 2024
Scientists have found a correlation between the intensity of nighttime outdoor lighting, which can disrupt sleep, and Alzheimer’s disease [1]. Light pollution – heavy consequences Outdoor lights help us with a lot of things, such as illuminating our streets and highways, discouraging crime, and so on.
Extracellular Vesicles to Fight Liver Fibrosis
September 16, 2024
Researchers have filled extracellular vesicles (EVs) with micro-RNA that is effective against liver fibrosis in mice and published their breakthrough in Aging Cell. The cellular postal service EVs, which cells use to send chemical messages and packages to one another, are significantly affected by aging to
Less Talk, More Work: Foresight/LBF Longevity Workshop 2024
September 13, 2024
When Foresight Institute and Longevity Biotech Fellowship joined forces, a one-of-a-kind longevity event emerged. Something different There’s a time-tested recipe for a scientific conference: people come on stage one by one, give talks, and receive tepid-to-warm applause, and then there’s a rush to the hall, where
A New Atlas for Cellular Rejuvenation
September 12, 2024
In Aging, researchers from Spain and Luxembourg have described the creation of Single-cell RNA-seq Investigation of Rejuvenation Agents and Longevity (SINGULAR), an atlas for cellular rejuvenation that describes how interventions affect individual cells. Computational biology might light up a better path These researchers begin this paper