Lifespan Research Institute

Category: News

Rejuvenation Roundup June 2024

Rejuvenation Roundup June 2024

Puzzle pieces are being fit together and connections are being made in understanding the massive number of biological changes that make up aging. Here’s how the science has progressed in

Hitting the brakes

70 Is Indeed the New 60, Study Suggests

Scientists have found that older people currently retain more youthful abilities than people who were the same age did in previous decades [1]. How miserable are we? Recent decades have

Walking Reduces Risk of Low Back Pain Recurrence

Publishing in The Lancet, scientists have shown that simple walking can have significant effects on the recurrence of back pain and disability metrics. Age-related and more than just annoying While

Fatty liver disease

A Reason Why Livers Accumulate Fat with Age

Researchers have discovered one of the reasons why fatty liver disease, even without alcohol consumption, increases with aging. The earliest stage of fatty liver disease Nonalcoholic fatty liver disease (NAFLD)

Long-tailed macaque face

A Protein Necessary for Corneal Healing

Researchers have discovered a protein that is necessary for proper healing of damaged corneal tissue and that this protein decreases with age. Repairing a shield that is easy to damage

Walker for frailty

Some Brain Changes May Cause Strength Loss

In Aging Cell, researchers have published data on a causal link between brain structure changes and age-related muscle loss (sarcopenia). Not just falls and frailty Sarcopenia is a key reason

Liver genetics

Treating Genetic Liver Diseases at Their Root

Researchers publishing in Cell Stem Cell have demonstrated that genetically diseased liver cells can be taken from human beings, altered in the laboratory, and used to regrow the livers of

Psoralea corylifolia

A Natural Compound as an Osteoporosis Treatment

A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound

Rejuvenation Roundup June 2024

Rejuvenation Roundup June 2024

Puzzle pieces are being fit together and connections are being made in understanding the massive number of biological changes that make up aging. Here’s how the science has progressed in June. LEAF News Team and activities Summer Could Be Big for Longevity Tech Investment: The weather

Choosing a clock

Developing a New Aging Clock for Medical Professionals

In Nature Aging, researchers have published the creation of a new clock that uses multiple metrics to evaluate biological aging. What’s worth measuring? Multiple metrics have been used to measure aging. The most commonly known in the literature are the epigenetic clocks, such as GrimAge and

Hitting the brakes

70 Is Indeed the New 60, Study Suggests

Scientists have found that older people currently retain more youthful abilities than people who were the same age did in previous decades [1]. How miserable are we? Recent decades have seen leaps in average life expectancy. However, those mostly stem from successes in curbing childhood mortality

Mitochondria

Encouraging Mitochondrial Maintenance to Fight Senescence

Researchers have published a method of rescuing cells from damaged mitochondria and cellular senescence, potentially alleviating major aspects of aging. Bad mitochondria must be consumed A core part of autophagy involves selective autophagy receptors (SARs), which build the autophagosomes in which the organelles are consumed [1].

Environmental Polystyrene

Blueberry Polyphenol May Relieve Plastic-Caused Sperm Damage

A recent paper has investigated the impact of polystyrene nanoplastics on the molecular processes of male reproductive tissues in mice [1]. Health risks of micro- and nanoplastics Microplastic and nanoplastic contamination is a worldwide public health concern for a good reason. Numerous research papers have associated

Sharp red brain

Study Links Stress to Mitochondrial Dysfunction in the Brain

For the first time, scientists have shown that the abundance of proteins needed for mitochondrial energy production in human brains is linked to perceived psychosocial experiences [1]. Picking the brains Negative psychosocial experiences have been linked to health problems by numerous studies. However, not enough is

Telomeres on chromosomes

New Drug Restores Telomerase, Improves Cognition in Mice

Scientists have identified a small molecule that upregulates telomerase reverse transcriptase (TERT) in multiple tissues, improving health and cognition in old mice. Telomere attrition and health The enzyme telomerase can prevent telomere attrition from happening by extending the length of telomeres. However, in most multicellular organisms,

Walking Reduces Risk of Low Back Pain Recurrence

Publishing in The Lancet, scientists have shown that simple walking can have significant effects on the recurrence of back pain and disability metrics. Age-related and more than just annoying While not as lethal as heart attacks and cancer, low back pain is also an age-related disease.

Fatty liver disease

A Reason Why Livers Accumulate Fat with Age

Researchers have discovered one of the reasons why fatty liver disease, even without alcohol consumption, increases with aging. The earliest stage of fatty liver disease Nonalcoholic fatty liver disease (NAFLD) begins with steatosis, the accumulation of fatty tissues in an organ [1], which can then progress

ISS Spacewalk

Combating How Space Travel Weakens Immune Function

It has been known for many years that microgravity in space interferes with human physiology in negative ways. As early as the first Apollo missions, astronauts experienced heart rhythm issues, low blood pressure, inner ear problems, and bone loss. Researchers at the Buck Institute have published

Long-tailed macaque face

A Protein Necessary for Corneal Healing

Researchers have discovered a protein that is necessary for proper healing of damaged corneal tissue and that this protein decreases with age. Repairing a shield that is easy to damage The corneal epithelium covers the cornea, which focuses light onto the retina of the eye. Although

Walker for frailty

Some Brain Changes May Cause Strength Loss

In Aging Cell, researchers have published data on a causal link between brain structure changes and age-related muscle loss (sarcopenia). Not just falls and frailty Sarcopenia is a key reason for the loss of independence among older people. Data on the prevalence of this gradual disorder

Elderly people eating healthy food

Mix of Lifestyle Interventions Might Reverse Alzheimer’s

In a randomized, controlled trial in humans, scientists have demonstrated that a multimodal lifestyle intervention consisting of a vegan diet, exercise, supplements, and stress management can improve the symptoms of Alzheimer’s [1]. Can we roll it back? Despite billions of dollars invested in finding a cure

Liver genetics

Treating Genetic Liver Diseases at Their Root

Researchers publishing in Cell Stem Cell have demonstrated that genetically diseased liver cells can be taken from human beings, altered in the laboratory, and used to regrow the livers of model mice. Recreating an entire organ has its own difficulties These researchers begin their paper by

Psoralea corylifolia

A Natural Compound as an Osteoporosis Treatment

A team of researchers has found that corylin, a compound previously investigated for its anti-senesence properties, is effective against osteoporosis in a mouse model. A return to a well-known compound Corylin is a compound that was first discovered in Psoralea corylifolia, a plant commonly used in