Lifespan Research Institute

Category: News

Vegan bowl

Wide-Ranging Benefits for Plant-Based Diets

A vast new study connects plant-based diets with various health benefits, including in cardiovascular diseases and cancer [1]. What exactly is healthy eating? Diet is one of the most powerful

Ovaries

Stem Cell Transplants for Ovarian Aging

Experiments in mouse models show the efficacy and safety of mesenchymal stem cell transplantation in treating ovarian aging [1]. Mesenchymal stem cells as a therapy Mesenchymal stem cells (MSCs) are

Mother and baby rat

NMN and NR Reverse Ovarian Aging in Rats

In a recent Pharmaceutical Research paper, the researchers explored the molecular processes through which the NAD+ precursors NMN and NR reversed ovarian aging in middle-aged rats [1]. Use it or

Kdineys

A New Potential Path to Treating Kidney Fibrosis

Researchers have found a new protein target for senescence-related kidney diseases and published their findings in Aging Cell. Kidney disease and fatty acid use Chronic kidney disease (CKD) is all

Mitochondria up close

Transplanting Mitochondria Improves Muscle Function

A recent study saw researchers associated with Cellvie demonstrate significant improvements to mitochondria and muscle function in aged mice by injecting additional mitochondria [1]. Mitochondrial dysfunction is a reason we

Elderly clinical trial

Stem Cells Alleviate Frailty in Clinical Trial

A placebo-controlled Phase 1/2 trial conducted in East Shanghai has found that administering umbilical cord-derived mesenchymal stem cells reduces frailty in older people. Stem cells against frailty These researchers begin

Vegan bowl

Wide-Ranging Benefits for Plant-Based Diets

A vast new study connects plant-based diets with various health benefits, including in cardiovascular diseases and cancer [1]. What exactly is healthy eating? Diet is one of the most powerful anti-aging interventions available today, but nutrition is also an extremely hard topic to analyze. Food we

Chronic pain

One Reason Why Older People Have Chronic Pain

Researchers have discovered a compound and a brain region that may be related to chronic pain in older people and published their findings in Aging Cell. When one sense doesn’t decline Aging destroys the senses over time, most notably sight and hearing [1]. Sensations related to

Nanoparticle

Plant Virus Nanoparticles Prevent Metastatic Cancers

Scientists have demonstrated that viral particles from a harmless plant virus can be used as an adjuvant therapy to prevent recurrence of disease and metastasis formation in several cancer models [1]. The challenge of keeping cancer at bay Medicine’s progress in treating cancer has been patchy:

Fast bicycling

Exercise May Remove Senescent Cells Through Inflammation

Exercise may be able to remove senescent cells only if acute inflammation is allowed to occur, according to a new study published in Aging. Inflammation and senescence Inflammation is known to be a critical part of aging, and its chronic accumulation has been labeled as a

Ovaries

Stem Cell Transplants for Ovarian Aging

Experiments in mouse models show the efficacy and safety of mesenchymal stem cell transplantation in treating ovarian aging [1]. Mesenchymal stem cells as a therapy Mesenchymal stem cells (MSCs) are stem cells derived from mesodermal tissue, such as the umbilical cord, umbilical cord blood, the placenta,

Evening exercise

Evening Aerobic Exercise Associated with Least Mortality

A new study suggests that aerobic medium-to-vigorous physical activity benefits obese and diabetic people the most when conducted in the evening hours [1]. Do you really need morning runs? Physical activity is an essential part of the longevity-conscious lifestyle and one of the best life-extending interventions

Hungry mouse

Aged Bacteria Increase Gut Inflammation in Younger Animals

Researchers have discovered negative ways in which intestinal bacteria change over time, spurring gut inflammation, and introduced older bacteria into a population of younger mice to determine their effects. A well-known link It has been thoroughly documented that gut bacteria have an influence on aging [1],

Cynomolgus Monkey

iPSC-derived Cardiomyocytes Rescue Heart Damage in Monkeys

Scientists have successfully used heart muscle cells created from induced pluripotent stem cells to counter the deleterious effects of heart attack in non-human primates. Reprogrammed cells for heart regeneration Since Dr. Yamanaka’s discovery, there has been a massive effort to turn this discovery into working therapies,

Upside and downside

Clearing Senescent Cells Can Be a Double-Edged Sword

Researchers have found that removing senescent cells makes it easier for mice to fight initial infections but harder for them to develop immune memory. Senescence and immunity Introducing their paper, the researchers discuss the SASP and the relationship of senescent cells to the immune system, noting

Longevity Desci Recap April 2024

Longevity and DeSci Recap – April 2024

In this latest edition of the Longevity and DeSci Recap, we’ll be taking a look back over a month full of events, research, and investments. As we head into spring, renewed life is on the horizon with continued investments in the longevity sector and the announcement

Mother and baby rat

NMN and NR Reverse Ovarian Aging in Rats

In a recent Pharmaceutical Research paper, the researchers explored the molecular processes through which the NAD+ precursors NMN and NR reversed ovarian aging in middle-aged rats [1]. Use it or lose it Female fertility decreases rather quickly in life. Aging leads to a decrease in the

Chromosomes

Exploring How Caloric Restriction Impacts Telomere Length

A recent study from Penn State University may shed more light on the link between telomeres, aging, and why caloric restriction appears to influence them. Telomeres are linked to aging Telomeres are small protective caps on the ends of our chromosomes that guard our DNA. Telomere

Kdineys

A New Potential Path to Treating Kidney Fibrosis

Researchers have found a new protein target for senescence-related kidney diseases and published their findings in Aging Cell. Kidney disease and fatty acid use Chronic kidney disease (CKD) is all too common in older people, as a full third of people over 70 have moderate to

Mitochondria up close

Transplanting Mitochondria Improves Muscle Function

A recent study saw researchers associated with Cellvie demonstrate significant improvements to mitochondria and muscle function in aged mice by injecting additional mitochondria [1]. Mitochondrial dysfunction is a reason we age Mitochondria are cellular powerhouses that convert nutrients into adenosine triphosphate (ATP), a form of energy

Elderly clinical trial

Stem Cells Alleviate Frailty in Clinical Trial

A placebo-controlled Phase 1/2 trial conducted in East Shanghai has found that administering umbilical cord-derived mesenchymal stem cells reduces frailty in older people. Stem cells against frailty These researchers begin by defining frailty as “a state of heightened vulnerability to potential stressors as a consequence of