Lifespan Research Institute

Category: News

Ruptured garbage bag

How Parkinson’s Disease Perpetuates Itself

A new paper elaborates on how and why microglia fail to clean up the α-synuclein protein of Parkinson’s disease, gradually making the disease worse. The aggregation of Parkinson’s Parkinson’s disease,

An Exercise-Related Protein May Protect the Heart

Researchers publishing in Aging have pinpointed a protein that increases after exercise and is associated with a reduced risk of coronary artery disease. The deadliest disease has inflammatory roots Coronary

Knee joint

Treating Arthritis with Rapamycin-Releasing Nanoparticles

Researchers have described how specialized nanoparticles, which deliver rapamycin and the antioxidant astaxanthin, restore macrophage balance and reduce inflammation in a mouse model of osteoarthritis. A matter of polarization Inflammation

Mikhail Batin

Mikhail Batin’s Crusade Against Aging

There’s no other way to put it: Mikhail (Misha) Batin is an oddball in the longevity space. In this field, which is populated mostly by scientists, entrepreneurs, and enthusiasts, Batin

Rabbit eating carrot

A Carrot Extract Improves the Metabolism of Old Mice

In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric

Elderly woman

Female-Specific Aging Trajectories Remain Understudied

In a recent Perspective published in Nature Aging, researchers noted a lack of studies on female-specific physiological factors on aging trajectories. They proposed solutions, including model systems, to address the

Rejuvenation Roundup December 2023

Rejuvenation Roundup December 2023

The holidays are over, and a new year has begun! However, festive celebrations weren’t the only things happening last month. Here’s the rejuvenation research and biotech developments that took place

Christmas Editorial

Best Christmas Wishes from Lifespan.io

The holidays are here, and it’s time for a well-earned rest and some festive fun with family and friends! We will take a look at what the Lifespan.io team has

LIN Report

Longevity Investor Network 2023 End of Year Update

The Longevity Investor Network has experienced significant growth and success over the past year. Our mission to connect innovative companies in the longevity sector with forward-thinking investors has seen remarkable

Andrew Steele Interview

Andrew Steele: “A Mindset Shift Is Required”

Andrew Steele is a physicist who became interested in longevity several years ago and began a career as a bioinformatician before becoming a longevity advocate, quickly making a name for himself with numerous media appearances. In 2021, Steele authored Ageless, which we reviewed back then, crowning

Ruptured garbage bag

How Parkinson’s Disease Perpetuates Itself

A new paper elaborates on how and why microglia fail to clean up the α-synuclein protein of Parkinson’s disease, gradually making the disease worse. The aggregation of Parkinson’s Parkinson’s disease, like Alzheimer’s, is characterized by protein aggregation. However, the affected neurons, the aggregates, and the pathology

Fat tissue communication

Improved Brain-Fat Communication Extends Lifespan in Mice

A new study suggests that the dysregulation of the crosstalk between hypothalamus and white adipose tissue affects aging. Rescuing this “communication channel” led to significant lifespan extension [1]. It’s all in your brain Thinking is not the brain’s sole responsibility. Some brain regions, such as the

An Exercise-Related Protein May Protect the Heart

Researchers publishing in Aging have pinpointed a protein that increases after exercise and is associated with a reduced risk of coronary artery disease. The deadliest disease has inflammatory roots Coronary artery disease directly kills more people than anything else in the world [1]. Its causes stem

Stress in pregnancy

Stress in Pregnancy Linked to Shorter Infant Telomeres

A new study published in BMC Psychiatry reviewed literature that links perceived stress during pregnancy with newborns’ telomere length [1]. Lifelong impact of telomere length Telomeres are protective caps at the end of chromosomes. The shortening of the telomeres, which happens with each DNA replication cycle

Medical records

David Sinclair on Human Trials of Anti-Aging Compounds

A new review authored by three acclaimed geroscientists paints a promising picture of past and ongoing human clinical trials of prospective anti-aging drugs [1]. From worms and mice to humans The biology of aging is an exciting new field, but most of its successes have been

Knee joint

Treating Arthritis with Rapamycin-Releasing Nanoparticles

Researchers have described how specialized nanoparticles, which deliver rapamycin and the antioxidant astaxanthin, restore macrophage balance and reduce inflammation in a mouse model of osteoarthritis. A matter of polarization Inflammation is a critical part of arthritis. Previous studies have found that inflammation of the membranes in

Happy mouse

TLR5 Activation Improves Health and Lifespan in Aged Mice

By activating toll-like receptor 5, an important element of the innate immune system, scientists have increased lifespan and improved multiple health measurements in old mice, despite having started the treatment late in life [1]. TLRs and aging The immune system gets dysregulated with age, driving multiple

Mikhail Batin

Mikhail Batin’s Crusade Against Aging

There’s no other way to put it: Mikhail (Misha) Batin is an oddball in the longevity space. In this field, which is populated mostly by scientists, entrepreneurs, and enthusiasts, Batin belongs to a different breed: activists. But, even among this small group, Batin is one of

Rabbit eating carrot

A Carrot Extract Improves the Metabolism of Old Mice

In Nature Communications, researchers have published their discovery of a compound found in carrots that promotes mitochondrial health and improves the physical abilities of older mice. Walking down the caloric restriction pathway Although it is difficult to establish in human beings, caloric restriction is one of

Elderly woman

Female-Specific Aging Trajectories Remain Understudied

In a recent Perspective published in Nature Aging, researchers noted a lack of studies on female-specific physiological factors on aging trajectories. They proposed solutions, including model systems, to address the issue [1]. Most model organisms don’t match human sex specificity The use of model organisms, such

Balance

Study Suggests Trade-Offs Between Reproduction and Lifespan

Scientists might have found support for the antagonistic pleiotropy theory of aging, which suggests that evolution selects some genetic traits that are associated with shorter lifespans because they also help us reproduce [1]. Evolution needs you to reproduce, not live long Shouldn’t evolution favor longer lifespans,

Rejuvenation Roundup December 2023

Rejuvenation Roundup December 2023

The holidays are over, and a new year has begun! However, festive celebrations weren’t the only things happening last month. Here’s the rejuvenation research and biotech developments that took place in December. LEAF News Best Christmas Wishes from Lifespan.io: In this holiday missive, we took a

Christmas Editorial

Best Christmas Wishes from Lifespan.io

The holidays are here, and it’s time for a well-earned rest and some festive fun with family and friends! We will take a look at what the Lifespan.io team has been up to recently, so sit back, relax, and enjoy a mince pie while you read

LIN Report

Longevity Investor Network 2023 End of Year Update

The Longevity Investor Network has experienced significant growth and success over the past year. Our mission to connect innovative companies in the longevity sector with forward-thinking investors has seen remarkable achievements, particularly in 2023. Investors On the investor side, we have now over 200 longevity investors