Category: News
Creating a New Clock with Medical Records
October 24, 2023
Assisted by TruDiagnostic, a team of researchers has published a preprint paper in which omics data has been used to create an epigenetic methylation clock. Why -omics? The researchers begin
New Insight Into How APOE4 Drives Alzheimer’s
October 24, 2023
A new study suggests that the gene variant APOE4 promotes Alzheimer’s disease by increasing gliosis, but this effect can be blocked by inhibiting the protein HMGB1 [1]. The dreaded E4
Pfizer-Backed VitaDAO Launches Biotech Company
October 23, 2023
VitaDAO, a decentralized autonomous organization (DAO), has launched its first biotech, Matrix Biosciences. This is a real milestone for new models of funding for the scientific community. The launch is
Sleep Disruption Leads to Cellular Senescence in Mice
October 23, 2023
A new preprint suggests that continuous sleep disruption might drive health problems via increased cellular senescence in visceral fat tissue [1]. Sleep and health Until recently, the impact of sleep
Remembering Where We Are in Alzheimer’s Research
October 22, 2023
A pair of neurologists have published a review in Cell discussing the current state of Alzheimer’s therapies, including drugs in early development, treatments in clinical trials, and therapies that are
High-Protein Diets Have Few Benefits in Mice
October 20, 2023
A new study suggests that high protein intake leads to fat gain and worse metabolic outcomes, but some of these effects are blocked by resistance training. Low protein consumption resulted
DNA Damage And Aging Of The Blood Vessels
October 19, 2023
In a paper published in Aging, researchers have explored the relationship between DNA damage and aging of the blood vessels. How arteries age This paper begins with some well-known facts
Treating Hypertension May Reduce Dementia Risk
October 18, 2023
Research published in JAMA Geriatrics analyzed the link between blood pressure, hypertension, and the risk of dementia [1]. Inconsistent research Published research is inconsistent regarding the link between hypertension and
The Longevity World Meets in Dublin for a Second Time
October 17, 2023
Last year’s inaugural Longevity Summit Dublin conference was a good start. Its second iteration, held in August this year, was universally acclaimed for being even bigger and better. Just like
Spermidine May Improve Egg Health and Fertility
October 16, 2023
Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm
Study Suggests a New Mechanism of Cellular Senescence
October 13, 2023
Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1].
Why Long-Lived Animals Are Needed for Life Extension Studies
October 12, 2023
A team of researchers, including Matt Kaeberlein and Brian Kennedy, has published a preprint discussing the necessity of using long-lived animals in life extension research. The Interventions Testing Program (ITP)
Correlations Between Omega-3 Fatty Acids and Brain Function
October 11, 2023
The authors of a study published in Brain Sciences have investigated the relationship between omega-3 fatty acid levels, brain volume, and cognitive function [1]. Aging and changes in the brain With
Journal Club October 2023 with Irina and Mike Conboy
October 11, 2023
The Journal Club returns on Friday October 27th at 11:30 am Eastern time on the Lifespan.io Facebook page. We will be discussing the new paper from Conboy et al. which
Help Us Solve Aging With Cryptocurrency
October 10, 2023
If you want to contribute to Lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We
Creating a New Clock with Medical Records
October 24, 2023
Assisted by TruDiagnostic, a team of researchers has published a preprint paper in which omics data has been used to create an epigenetic methylation clock. Why -omics? The researchers begin this preprint by discussing multiple biomarkers that are used to measure physical aging, including immune cell
New Insight Into How APOE4 Drives Alzheimer’s
October 24, 2023
A new study suggests that the gene variant APOE4 promotes Alzheimer’s disease by increasing gliosis, but this effect can be blocked by inhibiting the protein HMGB1 [1]. The dreaded E4 While scientists still do not know the precise causes of Alzheimer’s disease or how to treat
Pfizer-Backed VitaDAO Launches Biotech Company
October 23, 2023
VitaDAO, a decentralized autonomous organization (DAO), has launched its first biotech, Matrix Biosciences. This is a real milestone for new models of funding for the scientific community. The launch is in collaboration with Vera Gorbunova from the University of Rochester’s Aging Research Center and is well-known
Sleep Disruption Leads to Cellular Senescence in Mice
October 23, 2023
A new preprint suggests that continuous sleep disruption might drive health problems via increased cellular senescence in visceral fat tissue [1]. Sleep and health Until recently, the impact of sleep on human health was largely overlooked, including for healthcare professionals who work long hours. Now, scientists
Remembering Where We Are in Alzheimer’s Research
October 22, 2023
A pair of neurologists have published a review in Cell discussing the current state of Alzheimer’s therapies, including drugs in early development, treatments in clinical trials, and therapies that are prescribed today. The -mab drugs Monoclonal antibodies, drugs whose names end in -mab, have become the
High-Protein Diets Have Few Benefits in Mice
October 20, 2023
A new study suggests that high protein intake leads to fat gain and worse metabolic outcomes, but some of these effects are blocked by resistance training. Low protein consumption resulted in less muscle gain but did not affect strength [1]. The protein debate One of the
DNA Damage And Aging Of The Blood Vessels
October 19, 2023
In a paper published in Aging, researchers have explored the relationship between DNA damage and aging of the blood vessels. How arteries age This paper begins with some well-known facts about aging and cardiovascular risk. Cardiovascular disease is the single most common cause of death in
Treating Hypertension May Reduce Dementia Risk
October 18, 2023
Research published in JAMA Geriatrics analyzed the link between blood pressure, hypertension, and the risk of dementia [1]. Inconsistent research Published research is inconsistent regarding the link between hypertension and dementia. Some studies suggest an association between midlife hypertension and increased dementia risk. Other studies have
The Longevity World Meets in Dublin for a Second Time
October 17, 2023
Last year’s inaugural Longevity Summit Dublin conference was a good start. Its second iteration, held in August this year, was universally acclaimed for being even bigger and better. Just like the last time, this conference was marked by a considerable presence of longevity advocates alongside scientists
Spermidine May Improve Egg Health and Fertility
October 16, 2023
Reporters publishing in Nature Aging have identified a metabolite that appears to restore the age-related loss of quality of egg cells (oocytes) in mice. Spermidine is not just for sperm While it was originally found in semen, the metabolite spermidine has been found in many different
Study Suggests a New Mechanism of Cellular Senescence
October 13, 2023
Scientists have found that leakage of mitochondrial DNA in senescent cells is a major cause of their pro-inflammatory activity, and it can be targeted without clearing those cells out [1]. A new aspect of senescence Clearing senescent cells with drugs called senolytics is one of the
Why Long-Lived Animals Are Needed for Life Extension Studies
October 12, 2023
A team of researchers, including Matt Kaeberlein and Brian Kennedy, has published a preprint discussing the necessity of using long-lived animals in life extension research. The Interventions Testing Program (ITP) uncovers weaknesses The ITP is run by the National Institutes of Aging and described by these
Correlations Between Omega-3 Fatty Acids and Brain Function
October 11, 2023
The authors of a study published in Brain Sciences have investigated the relationship between omega-3 fatty acid levels, brain volume, and cognitive function [1]. Aging and changes in the brain With aging comes progressive changes in brain structure and ra eduction in cognitive abilities. The first changes
Journal Club October 2023 with Irina and Mike Conboy
October 11, 2023
The Journal Club returns on Friday October 27th at 11:30 am Eastern time on the Lifespan.io Facebook page. We will be discussing the new paper from Conboy et al. which examines current DNA methylation clocks and their limitations in the context of aging. They also developed
Help Us Solve Aging With Cryptocurrency
October 10, 2023
If you want to contribute to Lifespan.io and use cryptocurrency, there is a great opportunity happening right now to support our work! Donate to help us solve aging We promote the advancement of medical technologies that will increase healthy human longevity. By sponsoring, democratizing, and