Lifespan Research Institute

Category: News

Foreground Clock

Creating a Noise Clock to Measure Biological Age

Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression

Lower back pain

Senolytics as a Potential Back Pain Treatment

In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients

Mouse test

Exercise Mimetic Improves Memory In Old Mice

Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common

Trying to find a single cause of aging is like blinedfolded people trying to work out something is an elephant.

Is There a Single Essence of Aging?

In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging.

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club September 2023

The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature,

City smog

How Pollution Makes Aging Worse

A review paper published in GeroScience has detailed a substantial amount of research into the ways that environmental pollutants accelerate aging. A new model for an old problem This paper

Elderly hobbies

Having a Hobby Might Lead to a Healthier Life

A new publication in Nature Medicine has provided evidence from multiple countries supporting the idea that older people who have hobbies are healthier and less likely to have depression. Loneliness,

Chimeric DNA

Jumping Genes Influence the Speed of Aging in Worms

According to a newly published paper in Nature Communications, transposable elements impact aging in C.elegans [1]. Transposable elements and aging Transposable elements are often referred to as mobile genetic elements

An image of telomeres shortening which could lead to DNA damage.

Turning Back the Clock With mRNA Telomerase Therapy

Since its launch in 2016, Rejuvenation Technologies, located in Mountain View, California, has been developing a therapeutic to restore telomeres in humans. The company has been in stealth mode for

Liar at table

Two Industries in One Field

We are at an interesting time for our field, and at long last, some rejuvenation therapies are entering clinical trials. The approach of directly targeting the processes of aging in

Mouse on wheel

Metformin and Galantamine To Combat Muscle Loss

Researchers associated with Rejuvenate Biomed and publishing in JCI Insight have conducted multiple experiments on a combination of metformin and galantamine in animal models. These preclinical experiments are intended to

Developing a Treatment for Arthritis from Stem Cell Signals

Resarchers publishing in Aging have found that extracellular vesicles (EVs) derived from human umbilical cord mesenchymal stem cells (MSCs) reduce inflammatory markers in chondrocytes, which are responsible for building and maintaining human cartilage. An established approach This is far from the first attempt at treating osteoarthritis

Foreground Clock

Creating a Noise Clock to Measure Biological Age

Publishing in Aging, the Conboy research lab has outlined the problems with existing machine learning-based clocks and created a new clock based on epigenetic noise. The problem with linear regression This paper begins with a description of the elastic net, an artificial intelligence algorithm that powers

Lower back pain

Senolytics as a Potential Back Pain Treatment

In a recent paper, researchers from McGill University in Canada have investigated how a combination of two senolytics, RG-7112 and o-Vanillin, influences the intervertebral disc cells of back pain patients [1]. Back pain is a widespread issue An overwhelming majority of people, a full 80%, have

Mouse test

Exercise Mimetic Improves Memory In Old Mice

Researchers have identified a platelet-derived factor that improves cognition in mice and published their findings in Nature Communications. Finding the right molecules This paper begins with the same refrain common in discussions about the biological effects of exercise: the inability of some older people to conduct

Trying to find a single cause of aging is like blinedfolded people trying to work out something is an elephant.

Is There a Single Essence of Aging?

In the Proceedings of the National Academy of Science, Dr. Jesse Poganik and Prof. Vadim Gladyshev of Harvard Medical School have presented an opinion proposing a consensus understanding of aging. A problem of focus and funding The authors lament a lack of focus and funding in

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Stem Cell Signals Improve Cardiac Health in Old Rats

The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature, in which extracellular vesicles derived from neonatal cardiac progenitors produced significant rejuvenation in old rats and

The Journal Club is a monthly livestream hosted by Dr. Oliver Medvedik which covers the latest aging research papers.

Journal Club September 2023

The Journal Club returns with Dr. Oliver Medvedik on September 29th at 12:00 Eastern time on our Facebook page. We take a look at a recent study published in Nature, in which extracellular vesicles derived from neonatal cardiac progenitors produced significant rejuvenation in old rats and

City smog

How Pollution Makes Aging Worse

A review paper published in GeroScience has detailed a substantial amount of research into the ways that environmental pollutants accelerate aging. A new model for an old problem This paper begins with the well-known fact that age-related diseases, defined here as age-related non-communicable diseases (NCDs), are

Elderly hobbies

Having a Hobby Might Lead to a Healthier Life

A new publication in Nature Medicine has provided evidence from multiple countries supporting the idea that older people who have hobbies are healthier and less likely to have depression. Loneliness, social isolation, and hobbies This paper begins with an explanation of population aging and its downstream

Lifespan io Editorial

Ending Age-Related Diseases 2023: Longevity/DeSci Success

The Ending Age-Related Diseases 2023 conference has ended, and it was a big success. Today, we are delighted to announce that the first of our conference videos is available: the opening talk from the event given by our President, Keith Comito. But before we get into

Chimeric DNA

Jumping Genes Influence the Speed of Aging in Worms

According to a newly published paper in Nature Communications, transposable elements impact aging in C.elegans [1]. Transposable elements and aging Transposable elements are often referred to as mobile genetic elements or jumping genes, as these DNA pieces can change their position in the genome. Changing the

Elderly Situps

Taking Up Exercise Late in Life May Prevent Fitness Decline

According to a new study published in Aging Cell, previously sedentary old people who took up an exercise program were able to improve their fitness and maintain it for at least four years [1]. Better late than never When is it too late to engage in

An image of telomeres shortening which could lead to DNA damage.

Turning Back the Clock With mRNA Telomerase Therapy

Since its launch in 2016, Rejuvenation Technologies, located in Mountain View, California, has been developing a therapeutic to restore telomeres in humans. The company has been in stealth mode for a number of years, but there is finally some news! Reversing a decade of telomere loss

Liar at table

Two Industries in One Field

We are at an interesting time for our field, and at long last, some rejuvenation therapies are entering clinical trials. The approach of directly targeting the processes of aging in humans can finally be put to the test. While rejuvenation therapies that aim to prevent, stop,

Mouse on wheel

Metformin and Galantamine To Combat Muscle Loss

Researchers associated with Rejuvenate Biomed and publishing in JCI Insight have conducted multiple experiments on a combination of metformin and galantamine in animal models. These preclinical experiments are intended to be a prelude to a human trial for sarcopenia. A debilitating disease with no pharmaceutical treatments