Category: News
The Flavonoid Rutin May Suppress Senescent Cells
August 3, 2023
Researchers publishing in Aging Cell have documented some potential effects of rutin against senescence and cancer. Rutin is a natural compound found in several plants. Another compound to fight senescence
Impaired Calcium Uptake May Impact Long-Term Inflammation
August 3, 2023
Scientists have reported in Nature Aging that impaired mitochondrial uptake of calcium ions leads to changes in inflammatory responses that resemble what happens in aging [1]. Inflammation and aging Inflammation
Impact of Vitamin D Supplements on Mortality Risk
August 2, 2023
In a new study published in Nutrients, researchers analyzed the results of 80 randomized clinical trials and assessed the impact of vitamin D supplementation on mortality [1]. Vitamin D plays
Heterochronic Parabiosis Extends the Lives of Mice
August 1, 2023
For the first time, scientists have shown that letting young and old mice share blood leads to a significant lifespan extension in the old mouse [1]. Rejuvenation by young blood
Rejuvenation Roundup July 2023
August 1, 2023
Genetic and epigenetic studies abound this month, with a small molecule study making waves throughout the rejuvenation world. Let’s see what’s happened in July. LEAF News Peter Fedichev Explains His
Genetically Engineering Cells to Respond to Electricity
July 31, 2023
A paper published today in Nature Metabolism has described a method of genetically engineering cells to respond to electrical stimuli, allowing for on-demand gene expression. Finding a better trigger Despite
Young Brain Cells Outcompete Old Cells in a Mouse Model
July 28, 2023
In a mouse model of Huntington’s disease, scientists showed that injected young healthy brain cells can outcompete and eventually replace old, diseased ones. The results might be relevant for other
Neil Riordan on the Rising Tide of Stem Cell Therapies
July 27, 2023
“Stem Cell Therapy: A Rising Tide” by Neil Riordan is a comprehensive exploration of stem cell therapy along with its potential benefits, limitations, and prospects. The father of mesenchymal stem
Psychedelic Drugs for Alzheimer’s Treatment
July 27, 2023
A review article published in European Neuropsychopharmacology has described how and why psychedelic compounds may be useful in treating neurodegenerative diseases such as Alzheimer’s. A question of neuroplasticity Neuroplasticity refers
Some Age-Related Gene Expression Changes May Extend Life
July 26, 2023
In a recent paper published in Nucleic Acids Research, researchers analyzed the organs of several mammalian species, exploring gene expression patterns associated with maximum lifespan and finding surprising correlations [1].
Vigorous Weekend Exercise May Be Enough
July 26, 2023
A new study suggests that “weekend warriors”, people who only exercise for one or two days a week, enjoy similar cardiovascular benefits as those who exercise more regularly [1]. How
Review Links Statins to Insulin Resistance and Diabetes
July 25, 2023
A new systematic review lends support to the idea that statins, which are life-saving cholesterol-lowering drugs, are associated with an increased risk of insulin resistance and type 2 diabetes [1].
Metformin Protects Against Muscle Atrophy in Clinical Trial
July 24, 2023
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes
New System-Specific Epigenetic Clocks Revealed
July 21, 2023
A group of researchers led by Morgan Levine of Altos Labs has created a set of methylation clocks that can detect various aging patterns [1]. The less-than-perfect revolution The discovery
Repairing the Long-Term Damage of Smoking
July 20, 2023
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD
The Flavonoid Rutin May Suppress Senescent Cells
August 3, 2023
Researchers publishing in Aging Cell have documented some potential effects of rutin against senescence and cancer. Rutin is a natural compound found in several plants. Another compound to fight senescence In this study, the researchers place rutin among the many other natural compounds that have demonstrated
Impaired Calcium Uptake May Impact Long-Term Inflammation
August 3, 2023
Scientists have reported in Nature Aging that impaired mitochondrial uptake of calcium ions leads to changes in inflammatory responses that resemble what happens in aging [1]. Inflammation and aging Inflammation is an essential, evolutionarily conserved process and a fundamental part of the immune response, providing immediate
Impact of Vitamin D Supplements on Mortality Risk
August 2, 2023
In a new study published in Nutrients, researchers analyzed the results of 80 randomized clinical trials and assessed the impact of vitamin D supplementation on mortality [1]. Vitamin D plays essential roles in human health According to the CDC, 6.7% to 36.9% of Americans take vitamin
Heterochronic Parabiosis Extends the Lives of Mice
August 1, 2023
For the first time, scientists have shown that letting young and old mice share blood leads to a significant lifespan extension in the old mouse [1]. Rejuvenation by young blood Since the dawn of civilization, young blood has been credited with healing and rejuvenating powers, and
Rejuvenation Roundup July 2023
August 1, 2023
Genetic and epigenetic studies abound this month, with a small molecule study making waves throughout the rejuvenation world. Let’s see what’s happened in July. LEAF News Peter Fedichev Explains His Theory of Aging: Peter Fedichev, co-founder and CEO of Gero, is a relative newcomer to the
Genetically Engineering Cells to Respond to Electricity
July 31, 2023
A paper published today in Nature Metabolism has described a method of genetically engineering cells to respond to electrical stimuli, allowing for on-demand gene expression. Finding a better trigger Despite its futuristic outlook, this line of research is built upon previous work. The idea of an
Young Brain Cells Outcompete Old Cells in a Mouse Model
July 28, 2023
In a mouse model of Huntington’s disease, scientists showed that injected young healthy brain cells can outcompete and eventually replace old, diseased ones. The results might be relevant for other neurodegenerative diseases [1]. When neurons’ helpers fail The non-neuronal cells in the brain are collectively known
Neil Riordan on the Rising Tide of Stem Cell Therapies
July 27, 2023
“Stem Cell Therapy: A Rising Tide” by Neil Riordan is a comprehensive exploration of stem cell therapy along with its potential benefits, limitations, and prospects. The father of mesenchymal stem cell research, Arnold Caplan, dubbed Riordan as a pioneering figure in stem cell research and application.
Psychedelic Drugs for Alzheimer’s Treatment
July 27, 2023
A review article published in European Neuropsychopharmacology has described how and why psychedelic compounds may be useful in treating neurodegenerative diseases such as Alzheimer’s. A question of neuroplasticity Neuroplasticity refers to the ability of neurons to remodel themselves, forming new connections in response to stimuli. Many
Some Age-Related Gene Expression Changes May Extend Life
July 26, 2023
In a recent paper published in Nucleic Acids Research, researchers analyzed the organs of several mammalian species, exploring gene expression patterns associated with maximum lifespan and finding surprising correlations [1]. How and why gene expression changes As organisms age, their gene activity patterns change. To understand
Vigorous Weekend Exercise May Be Enough
July 26, 2023
A new study suggests that “weekend warriors”, people who only exercise for one or two days a week, enjoy similar cardiovascular benefits as those who exercise more regularly [1]. How crucial is a daily run? The consensus of medical studies practically implores people to engage in
Review Links Statins to Insulin Resistance and Diabetes
July 25, 2023
A new systematic review lends support to the idea that statins, which are life-saving cholesterol-lowering drugs, are associated with an increased risk of insulin resistance and type 2 diabetes [1]. Statins’ dark side Statins, drugs that improve the lipid profile by reducing harmful LDL cholesterol, are
Metformin Protects Against Muscle Atrophy in Clinical Trial
July 24, 2023
Researchers publishing in Aging Cell have documented a human clinical trial showing that metformin reduces atrophy caused by long periods of bed rest. A common problem and a well-known diabetes drug Long periods of disuse cause muscles to atrophy and accelerate the age-related muscle wasting known
New System-Specific Epigenetic Clocks Revealed
July 21, 2023
A group of researchers led by Morgan Levine of Altos Labs has created a set of methylation clocks that can detect various aging patterns [1]. The less-than-perfect revolution The discovery that genome methylation patterns correlate with various processes of aging led to the development of methylation
Repairing the Long-Term Damage of Smoking
July 20, 2023
Researchers publishing in Aging Cell have described how treating the increased senescent cell burden that comes with cigarette smoke exposure can repair some of the damage. Senescent cells and COPD Chronic obstructive pulmonary disorder (COPD) and idiopathic pulmonary fibrosis (IPF), both of which are well-known consequences