Category: News
Dr. Nir Barzilai on How to Age Later
March 27, 2023
In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a
Ashley Zehnder on Harnessing Animal Genes Against Aging
March 24, 2023
Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling.
Promoting Muscle Regeneration With an Immune Factor
March 23, 2023
A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons
Journal Club March 2023 + Zoom Connection Details
March 23, 2023
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which
Long-Term Resistance Exercise Increases Autophagy
March 22, 2023
In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy Disabled autophagy was
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes,
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions
Sleep Apnea and Inflammatory Biomarkers of Tooth Decay
March 16, 2023
A study published in Heliyon has explained a relationship between sleep apnea and an increase of inflammatory factors in the mouth that are connected to the gum disease peridontitis. Connected
Inflammation Strongly Predicts Mortality After Statin Use
March 16, 2023
Analyzing data from three clinical trials, scientists have shown that excessive inflammation is a much stronger predictor of cardiovascular and all-cause mortality in patients on statins than excessive LDL cholesterol
Excessive Fat, Not Sugar, Leads to Obesity in Mice
March 15, 2023
In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it
Epigenetic Biomarker for Measuring Aging Through Fitness
March 15, 2023
A new biomarker for measuring biological aging based on physical fitness has been published in Aging, and it has been found to be useful in predicting health issues. A clock
Prof. George Church on Cellular Reprogramming and Longevity
March 14, 2023
Professor of Genetics at Harvard Medical School, a veteran geroscientist, and a serial entrepreneur, George Church hardly needs an introduction. While we are always happy to discuss the present and
Mitochondria, DNA, and Oxidative Stress
March 13, 2023
A paper published in Experimental Gerontology has provided a fresh and detailed look at the effects of oxidative stress on longevity. Revisiting an old theory The free radical theory of
Dr. Nir Barzilai on How to Age Later
March 27, 2023
In “Age Later: Healthspan, Lifespan, and the New Science of Longevity,” Dr. Nir Barzilai provides an insightful and comprehensive overview of the latest research on aging and longevity. As a renowned gerontologist and the director of the Institute for Aging Research at the Albert Einstein College
Ashley Zehnder on Harnessing Animal Genes Against Aging
March 24, 2023
Many species have developed amazing mechanisms to cope with various drivers of aging. We have previously interviewed two prominent experts that study those evolutionary marvels: Steven Austad and Emma Teeling. However, this research is not purely academic anymore. A handful of bold entrepreneurs are trying to
Promoting Muscle Regeneration With an Immune Factor
March 23, 2023
A paper published today in Nature Aging has shown that a macrophage-regulating factor has a significant impact on muscle regeneration. Healing slows with aging The researchers note two key reasons for the decline of regenerative abilities with aging. The first is stem cell exhaustion, the gradual
Journal Club March 2023 + Zoom Connection Details
March 23, 2023
The Journal Club returns on Tuesday 28th March at 12:00 PM Eastern time to the lifespan.io Facebook channel. This month Dr. Oliver Medvedik will be exploring a recent study which looked at the effects of prolonged fasting on human macrophages and how metabolites from that fasting
Long-Term Resistance Exercise Increases Autophagy
March 22, 2023
In a new systemic review published in Autophagy Reports, researchers have demonstrated that exercise plays a role in regulating autophagy, depending on its type [1]. Manipulating autophagy Disabled autophagy was recently acknowledged as a hallmark of aging. Indeed, boosting the ability of cells to get rid
Mediterranean Diet Might Lower Risk of Dementia
March 21, 2023
In a large-scale observational study, British scientists have shown that high levels of adherence to the Mediterranean diet might substantially lower the risk of dementia [1]. A healthy diet The Mediterranean diet, which is based on ingredients such as olive oil, vegetables, legumes, fish, and whole
Vital Muscle Enzyme Declines With Aging
March 20, 2023
Research published in Nature Metabolism has described PCYT2, an enzyme essential for muscle function, and how it declines with aging. A necessary lipid synthesizer in muscle Human beings need PCYT2 as part of the Kennedy pathway to synthesize two critical components of the phosopholipid membrane that
The Human Cost of Metabolic Diseases
March 17, 2023
A new paper published in Cell Metabolism has shown the growing influence of metabolic diseases in an aging population. Related diseases studied together Metabolic diseases include hypertension, type 2 diabetes, hyperlipidemia, obesity, and non-alcoholic fatty liver disease [1]. These diseases, representing fundamental problems with how the
Rep. Bilirakis on the Longevity Science Caucus
March 17, 2023
We in the longevity field have received powerful allies on Capitol Hill with the creation of the bipartisan Congressional Caucus for Longevity Science. We had the opportunity to ask questions of one of its co-chairs. Longevity is bipartisan The fight against aging must become one of
Sleep Apnea and Inflammatory Biomarkers of Tooth Decay
March 16, 2023
A study published in Heliyon has explained a relationship between sleep apnea and an increase of inflammatory factors in the mouth that are connected to the gum disease peridontitis. Connected dangers This paper begins with a discussion of peridontitis, which is caused by infection with anaerobic
Inflammation Strongly Predicts Mortality After Statin Use
March 16, 2023
Analyzing data from three clinical trials, scientists have shown that excessive inflammation is a much stronger predictor of cardiovascular and all-cause mortality in patients on statins than excessive LDL cholesterol levels. These findings can upend the current standard of care for such patients [1]. The two
Excessive Fat, Not Sugar, Leads to Obesity in Mice
March 15, 2023
In a new study published in Endocrinology and Metabolism, researchers have shown that fat rather than sugar is the macronutrient that drives obesity and other detrimental metabolic changes if it constitutes a large proportion of dietary calories [1]. Obesity, diet, and the microbiome Obesity is associated
Epigenetic Biomarker for Measuring Aging Through Fitness
March 15, 2023
A new biomarker for measuring biological aging based on physical fitness has been published in Aging, and it has been found to be useful in predicting health issues. A clock with a different purpose Epigenetic clocks are most notable for their direct relationship to biological age,
Prof. George Church on Cellular Reprogramming and Longevity
March 14, 2023
Professor of Genetics at Harvard Medical School, a veteran geroscientist, and a serial entrepreneur, George Church hardly needs an introduction. While we are always happy to discuss the present and future of geroscience with him, this interview focuses on the two gene therapy papers that he
Mitochondria, DNA, and Oxidative Stress
March 13, 2023
A paper published in Experimental Gerontology has provided a fresh and detailed look at the effects of oxidative stress on longevity. Revisiting an old theory The free radical theory of aging, which purports that reactive oxygen species (ROS) are the core driver of aging, was developed