Category: News
New Treatment Alleviates Depression Symptoms in Mice
March 10, 2023
Scientists have shown that the protein GDF11 can reverse depression-like symptoms in naturally aged mice and in a mouse model of depression. Depressed humans have lower GDF11 as well [1].
Young Blood Alters Gene Expression in Old Brain Cells
March 9, 2023
Research published today in Nature Aging has shown that heterochronic parabiosis, the circulatory joining of young and old organisms, has rejuvenative effects on the gene expression of multiple types of
Metformin and Rapamycin Rejuvenate Stem Cells in Mice
March 8, 2023
In a new study published in Aging Cell, researchers have shown that two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of
New Small Molecule Alleviates Alzheimer’s in Mouse Model
March 7, 2023
Scientists have developed a custom-made molecule that targets a post-translationally modified kinase linked to Alzheimer’s, improving symptoms in a murine model of the disease [1]. A novel approach to neutralizing
Extracellular Vesicles as a Hallmark of Aging
March 6, 2023
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own
How NAD+ Relates to Smell Loss with Age
March 3, 2023
Researchers publishing in Aging Cell have elucidated a relationship between aging, the loss of smell, and NAD+ in a mouse model. Olfactory ability declines with age Roughly half of people
Prof. Tzipi Strauss on the Upcoming Longevity Center
March 3, 2023
Despite its small size, Israel is packing quite a punch when it comes to innovation, having earned the moniker “the startup nation”. It also has advanced healthcare and some of
Insider Insight: Meet the Organizers of LongHack
March 2, 2023
LongHack, the longevity hackathon hosted by DeSci organization VitaDAO, was held on January 20th-23rd, 2023. Gathering researchers, developers, and other interested parties to create new tools and solutions for longevity,
Exercise and Supplements Against Age-Related Inflammation
March 2, 2023
In a new systematic review, researchers have shown that combining some dietary supplements and exercise might be beneficial for people over the age of 60 [1]. A double-edged sword Chronic
Association Between BMI and Mortality Revisited
March 1, 2023
In a new paper, Ryan K. Masters, professor at CU Boulder, suggests that when adjusted for body shape and lifelong shifts, the relationship between BMI and mortality is more linear
Rejuvenation Roundup February 2023
March 1, 2023
We continue to grow as an organization and in readership, but the fight against aging is far from over. Here’s what’s been done in February. lifespan.io News Team and activities
Ending Atherosclerosis: Cyclarity and Dr. Matthew O’Connor
February 28, 2023
Cyclarity Therapeutics is striving to make powerful treatments for cardiovascular disease and, most importantly, make them accessible and affordable. Their cutting-edge cyclodextrin technology targets atherosclerosis, aiming to eliminate the buildup
Chris Mirabile on the NOVOS Approach
February 28, 2023
With multiple experts on its scientific advisory board, NOVOS offers supplements containing ingredients that recent research has linked to longevity. This company also markets biological age tests for people who
Nonlinear Analysis for a Better Epigenetic Clock
February 27, 2023
A team publishing in Human Genomics has developed a new model for analyzing epigenetic changes that uses nonlinear analysis. Current clocks are linear Current epigenetic clocks, including the original Horvath
Senescent Cells Contribute to Brain Cancer
February 26, 2023
Combining results from human tumors and a mouse model, researchers publishing in Nature Communications have shown that senescent cells promote the growth of glioblastoma, a form of brain cancer. Deadly,
New Treatment Alleviates Depression Symptoms in Mice
March 10, 2023
Scientists have shown that the protein GDF11 can reverse depression-like symptoms in naturally aged mice and in a mouse model of depression. Depressed humans have lower GDF11 as well [1]. Depression and aging Severe mental disorders, including depression, have been linked to significantly shorter lifespans [2].
Young Blood Alters Gene Expression in Old Brain Cells
March 9, 2023
Research published today in Nature Aging has shown that heterochronic parabiosis, the circulatory joining of young and old organisms, has rejuvenative effects on the gene expression of multiple types of brain cells in mice. Parabiosis affects a wide variety of factors at once Heterochronic parabiosis is
Metformin and Rapamycin Rejuvenate Stem Cells in Mice
March 8, 2023
In a new study published in Aging Cell, researchers have shown that two promising anti-aging agents, the antibiotic rapamycin and the anti-diabetic drug metformin, reverse aging in a population of intestinal stem cells [1]. The aging intestine Older people are more prone to gastrointestinal problems [2].
New Small Molecule Alleviates Alzheimer’s in Mouse Model
March 7, 2023
Scientists have developed a custom-made molecule that targets a post-translationally modified kinase linked to Alzheimer’s, improving symptoms in a murine model of the disease [1]. A novel approach to neutralizing proteins MAPK is a family of kinases involved in numerous cellular processes. One member of this
Extracellular Vesicles as a Hallmark of Aging
March 6, 2023
A review paper published in Cells has described multiple ways in which the secretion of extracellular vesicles (EVs) changes with aging, leading the authors to propose it as its own hallmark. Extracellular vesicles and their uses This review begins with an outline and explanation of extracellular
How NAD+ Relates to Smell Loss with Age
March 3, 2023
Researchers publishing in Aging Cell have elucidated a relationship between aging, the loss of smell, and NAD+ in a mouse model. Olfactory ability declines with age Roughly half of people over the age of 65 experience a decreased ability to smell [1], and research has shown
Prof. Tzipi Strauss on the Upcoming Longevity Center
March 3, 2023
Despite its small size, Israel is packing quite a punch when it comes to innovation, having earned the moniker “the startup nation”. It also has advanced healthcare and some of the best hospitals in the world. In one of them, Sheba Medical Center, the first-of-its-kind Longevity
Insider Insight: Meet the Organizers of LongHack
March 2, 2023
LongHack, the longevity hackathon hosted by DeSci organization VitaDAO, was held on January 20th-23rd, 2023. Gathering researchers, developers, and other interested parties to create new tools and solutions for longevity, ten teams competed to impress the judging panel and take home prizes: 5,500 VITA and 3,500
Exercise and Supplements Against Age-Related Inflammation
March 2, 2023
In a new systematic review, researchers have shown that combining some dietary supplements and exercise might be beneficial for people over the age of 60 [1]. A double-edged sword Chronic low-level inflammation accompanies many hereditary and age-associated diseases. Inflammation also plays an important role in ‘healthy’
Association Between BMI and Mortality Revisited
March 1, 2023
In a new paper, Ryan K. Masters, professor at CU Boulder, suggests that when adjusted for body shape and lifelong shifts, the relationship between BMI and mortality is more linear and robust than previously thought, with normal BMI being the healthiest [1]. BMI’s many problems Most
Rejuvenation Roundup February 2023
March 1, 2023
We continue to grow as an organization and in readership, but the fight against aging is far from over. Here’s what’s been done in February. lifespan.io News Team and activities Our Organization Grows to Support Rejuvenation Research: Spring is not far away here in the Northern
Ending Atherosclerosis: Cyclarity and Dr. Matthew O’Connor
February 28, 2023
Cyclarity Therapeutics is striving to make powerful treatments for cardiovascular disease and, most importantly, make them accessible and affordable. Their cutting-edge cyclodextrin technology targets atherosclerosis, aiming to eliminate the buildup of non-degradable oxidized cholesterol that gets stuck inside cells in the arterial walls. The company has
Chris Mirabile on the NOVOS Approach
February 28, 2023
With multiple experts on its scientific advisory board, NOVOS offers supplements containing ingredients that recent research has linked to longevity. This company also markets biological age tests for people who want to monitor their progress. We spoke with NOVOS founder and CEO Chris Mirabile about the
Nonlinear Analysis for a Better Epigenetic Clock
February 27, 2023
A team publishing in Human Genomics has developed a new model for analyzing epigenetic changes that uses nonlinear analysis. Current clocks are linear Current epigenetic clocks, including the original Horvath clock and the death-predicting GrimAge, use linear analyses of methylation sites to estimate biological age. However,
Senescent Cells Contribute to Brain Cancer
February 26, 2023
Combining results from human tumors and a mouse model, researchers publishing in Nature Communications have shown that senescent cells promote the growth of glioblastoma, a form of brain cancer. Deadly, aggressive, and hard to treat Glioblastoma is one of the most dangerous forms of cancer. Even