Category: News
Removal of Neuronal APOE4 Alleviates Alzheimer’s in Mice
February 24, 2023
In a new study published in Nature Aging, scientists have shown that targeted ablation of neuronal APOE4, which produces the ApoE4 protein, significantly protects against Alzheimer’s disease in a mouse
The State of the Art in Immune Cell Therapy
February 23, 2023
A pair of researchers from Stanford University have published a detailed review of the current state of CAR T immune cell therapies in Nature. A new state of the art
Caloric Restriction Might Slow Down Human Aging
February 22, 2023
In a paper published in Nature Aging, researchers have shown that caloric restriction modestly slows down the pace of aging in healthy young people as measured by one of the
High Protein Intake Associated With Sarcopenia
February 22, 2023
Researchers publishing in Age and Ageing have found that, rather than being protective, an increase in dietary protein is associated with an increased chance of sarcopenia. Sarcopenia is a well-known
Our Organization Grows to Support Rejuvenation Research
February 22, 2023
Spring is not far away here in the Northern Hemisphere, and with it, the signs of life and new growth are appearing. Much like the change of seasons, our organization
Midday Exercise Might Be Better In Preventing Mortality
February 21, 2023
Scientists have found that the time of day when you exercise might be an important factor in lowering all-cause and cardiovascular mortality [1]. Exercise is good, but what about timing?
Journal Club February 2023
February 21, 2023
The Journal Club, hosted by Dr. Oliver Medvedik, returns to the lifespan.io Facebook page at 12:00 on Tuesday, February 28th. This month, we are covering a recent paper that showed
Reviewing David Sinclair’s First Lifespan Book
February 20, 2023
David Sinclair, PhD, esteemed molecular geneticist at Harvard, believes that aging is a disease that should be attacked at its roots. Furthermore, he believes if we are to make efficient
High Cholesterol Associated With Lower Bone Mineral Density
February 18, 2023
A team of researchers has described an association between reduced bone density in the lumbar spine and high total cholesterol in a paper published in Aging. Previous studies were conflicting
Nicotinamide Riboside Improves Muscle Energy in Trial
February 17, 2023
Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is
Human Organoids for Brain Regeneration
February 16, 2023
Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do
Young Ovarian Tissue Rejuvenates Old Mice
February 15, 2023
In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1].
Lithium Is Linked to Lower Mortality
February 14, 2023
In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a
The Link Between NAD+ and Heart Failure
February 13, 2023
A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of
Meet hack-age, Winners of the January 2023 LongHack
February 10, 2023
On January 22nd, hack-age won the 2023 LongHack competition, which carried a grand prize of 5,500 VITA and 3,500 USD. lifespan.io caught up with the team behind the winning project
Removal of Neuronal APOE4 Alleviates Alzheimer’s in Mice
February 24, 2023
In a new study published in Nature Aging, scientists have shown that targeted ablation of neuronal APOE4, which produces the ApoE4 protein, significantly protects against Alzheimer’s disease in a mouse model [1]. The dreadful allele An infamous variant of the APOE gene, APOE4, is the strongest
The State of the Art in Immune Cell Therapy
February 23, 2023
A pair of researchers from Stanford University have published a detailed review of the current state of CAR T immune cell therapies in Nature. A new state of the art in fighting cancer Chimeric antigen receptor (CAR) is a technology that allows researchers to alter T
Caloric Restriction Might Slow Down Human Aging
February 22, 2023
In a paper published in Nature Aging, researchers have shown that caloric restriction modestly slows down the pace of aging in healthy young people as measured by one of the DNA methylation clocks [1]. CALERIE design A plethora of animal data has shown beneficial effects of
High Protein Intake Associated With Sarcopenia
February 22, 2023
Researchers publishing in Age and Ageing have found that, rather than being protective, an increase in dietary protein is associated with an increased chance of sarcopenia. Sarcopenia is a well-known disorder that occurs with aging. People with sarcopenia lack adequate muscular function, leading to frailty, a
Our Organization Grows to Support Rejuvenation Research
February 22, 2023
Spring is not far away here in the Northern Hemisphere, and with it, the signs of life and new growth are appearing. Much like the change of seasons, our organization is also growing and preparing to continue the fight against age-related diseases. Matt Kaeberlein joins our
Midday Exercise Might Be Better In Preventing Mortality
February 21, 2023
Scientists have found that the time of day when you exercise might be an important factor in lowering all-cause and cardiovascular mortality [1]. Exercise is good, but what about timing? The value of physical activity for health and longevity is unquestionable [2], even if some doubts
Journal Club February 2023
February 21, 2023
The Journal Club, hosted by Dr. Oliver Medvedik, returns to the lifespan.io Facebook page at 12:00 on Tuesday, February 28th. This month, we are covering a recent paper that showed a method of restoring youthful collagen production in aged skin [1]. If you would like some
Reviewing David Sinclair’s First Lifespan Book
February 20, 2023
David Sinclair, PhD, esteemed molecular geneticist at Harvard, believes that aging is a disease that should be attacked at its roots. Furthermore, he believes if we are to make efficient and sensible use our medical resources, we must move away from the “whack-a-mole” approach to treating
High Cholesterol Associated With Lower Bone Mineral Density
February 18, 2023
A team of researchers has described an association between reduced bone density in the lumbar spine and high total cholesterol in a paper published in Aging. Previous studies were conflicting In various populations, conflicting evidence has been found regarding a relationship between cholesterol and bone density.
Nicotinamide Riboside Improves Muscle Energy in Trial
February 17, 2023
Scientists have shown that long-term treatment with a popular NAD+ precursor can raise NAD+ levels in blood and muscle and increase mitochondria content and function [1]. Twin-based design NAD+ is an important coenzyme that performs multiple functions, including mitochondrial energy production. NAD+ levels decrease with aging,
Human Organoids for Brain Regeneration
February 16, 2023
Researchers publishing in Cell Stem Cell have used organoids derived from human cells to regrow the brain tissue of rats. The need to repair permanent damage While human beings do generate new neurons (neurogenesis) [1], this ability is very limited, in both region and amount. Brain
Young Ovarian Tissue Rejuvenates Old Mice
February 15, 2023
In a paper published in Frontiers in Endocrinology, researchers have shown that transplanted young ovarian tissue improves the immune function of old recipient mice even if they are hormone-depleted [1]. Not just a reproductive matter Although women generally live longer than men, women spend almost half
Lithium Is Linked to Lower Mortality
February 14, 2023
In an epidemiological study published in Aging, scientists have shown that patients who take lithium have much lower all-cause mortality than patients on other psychotropic drugs [1]. Is lithium a longevity drug? Lithium has long been prescribed for certain psychiatric conditions, mainly bipolar disorder. With time,
The Link Between NAD+ and Heart Failure
February 13, 2023
A paper published today in Nature Cardiovascular Research has explained a relationship between dilated cardiac myopathy (DCM), epigenetic dysregulation, NAD+, and the epigenetic regulatory molecule Kdm8. A gradual decline of ability DCM occurs when the left ventricle of the heart becomes enlarged and loses its ability
Meet hack-age, Winners of the January 2023 LongHack
February 10, 2023
On January 22nd, hack-age won the 2023 LongHack competition, which carried a grand prize of 5,500 VITA and 3,500 USD. lifespan.io caught up with the team behind the winning project to learn more about their idea and their experience competing in the hackathon. What is LongHack?