Category: News
The Effects of Niacin on Alzheimer’s in Mice
November 14, 2022
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer’s and outlined the genes involved. Niacin’s known effects
Protein Intake Increases Bone Density in Older Adults
November 11, 2022
Scientists have found that animal protein consumption positively correlates with bone density in older adults. Things become more complicated regarding plant protein [1]. Too little or too much? Just
Harnessing Senescent Cancer Cells to Fight Cancer
November 10, 2022
New research published in Cancer Discovery has outlined a potential new method of using senescent cells to encourage the immune system to attack cancer [1]. Senescent cancer cells and immune
Astaxanthin Improves Endurance in Older Adults
November 9, 2022
In a new study published in International Journal of Environmental Research and Public Health, Japanese researchers have shown that astaxanthin supplementation improves endurance in healthy older adults [1]. Muscles succumb
Dr. Matt Kaeberlein on WormBot and the Dog Aging Project
November 8, 2022
Dr. Matt Kaeberlein is a heavy hitter in the longevity field. While his name has become associated with the Dog Aging Project that he started a few years ago, his
Extracellular Vesicles from Young Stem Cells Rejuvenate Mice
November 8, 2022
Scientists have shown that injection of extracellular vesicles secreted by young adipose-derived stem cells increases fitness and promotes tissue rejuvenation in aged mice [1]. Mode of communication Small extracellular vesicles
Gene Therapy to Delay Reproductive Senescence
November 7, 2022
A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through
Lou Hawthorne, NaNotics on Cleaning Blood with Nanoparticles
November 4, 2022
Lou Hawthorne is the founder and CEO of NaNotics, a biotech company that creates nanoparticles that can soak up harmful molecules in circulation. This paradigm-shifting technology can be used to
Protecting Memory Through Gut Bacteria
November 3, 2022
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory
Klotho Reduces Arterial Calcification Through Autophagy
November 2, 2022
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition
Cellular Reprogramming Extends Lifespan, Healthspan in Mice
November 1, 2022
Scientists have shown that continuous low-dose induction of reprogramming factors and a single early life reprogramming treatment both significantly increase lifespan and healthspan in progeroid mice while altering their
Rejuvenation Roundup October 2022
November 1, 2022
Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in
Vitamin D Combats Oxidative Stress in Gingival Cells
October 31, 2022
A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes
Turn.bio Announces Preliminary Results of a CAR-T Cell Study
October 28, 2022
Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro. Turn.bio, a developer of mRNA-based
New Compounds Beat Resveratrol in Sirtuin Activation
October 27, 2022
A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and
The Effects of Niacin on Alzheimer’s in Mice
November 14, 2022
A study published in the Annals of Translational Medicine has shown the effects of niacin supplementation on a mouse model of Alzheimer’s and outlined the genes involved. Niacin’s known effects Niacin supplementation has been previously researched in its effects on neurological diseases: we have discussed its
Protein Intake Increases Bone Density in Older Adults
November 11, 2022
Scientists have found that animal protein consumption positively correlates with bone density in older adults. Things become more complicated regarding plant protein [1]. Too little or too much? Just how much protein people should consume has been a point of contention. Decades-old research, performed mainly
Harnessing Senescent Cancer Cells to Fight Cancer
November 10, 2022
New research published in Cancer Discovery has outlined a potential new method of using senescent cells to encourage the immune system to attack cancer [1]. Senescent cancer cells and immune clearance Cellular senescence is a stress response [2], and cancer cells within tumors undergo significant stress:
Astaxanthin Improves Endurance in Older Adults
November 9, 2022
In a new study published in International Journal of Environmental Research and Public Health, Japanese researchers have shown that astaxanthin supplementation improves endurance in healthy older adults [1]. Muscles succumb to oxidative stress Aging leads to reduced muscle strength and endurance. Currently, exercising is the only
Dr. Matt Kaeberlein on WormBot and the Dog Aging Project
November 8, 2022
Dr. Matt Kaeberlein is a heavy hitter in the longevity field. While his name has become associated with the Dog Aging Project that he started a few years ago, his research interests span much wider. Besides an update on the Dog Aging Project, which is still
Extracellular Vesicles from Young Stem Cells Rejuvenate Mice
November 8, 2022
Scientists have shown that injection of extracellular vesicles secreted by young adipose-derived stem cells increases fitness and promotes tissue rejuvenation in aged mice [1]. Mode of communication Small extracellular vesicles are one of the ways in which cells communicate with each other [2]. Basically, cells engulf
Gene Therapy to Delay Reproductive Senescence
November 7, 2022
A team of Spanish researchers publishing in Aging have reported that they can delay reproductive senescence in female rats by stimulating the production of insulin growth factor 1 (IGF-1) through gene therapy. A well-studied approach IGF-1 is a well-known anti-inflammatory compound, having shown positive effects in
Lou Hawthorne, NaNotics on Cleaning Blood with Nanoparticles
November 4, 2022
Lou Hawthorne is the founder and CEO of NaNotics, a biotech company that creates nanoparticles that can soak up harmful molecules in circulation. This paradigm-shifting technology can be used to fight cancer as well as various inflammatory disorders, such as sepsis, which kills more people than
Protecting Memory Through Gut Bacteria
November 3, 2022
Researchers publishing in Nutrients have shown that adding a strain of lactic acid bacteria to the gut flora of older, memory-impaired people partially alleviates their memory problems. A specific anti-inflammatory bacterium The researchers begin their paper by noting that mild cognitive impairment (MCI) is associated with
Klotho Reduces Arterial Calcification Through Autophagy
November 2, 2022
In a new study published in Oxidative Medicine and Cellular Longevity, the researchers have shown that klotho ameliorates vascular calcification via increased autophagy [1]. ‘Rusty’ arteries Vascular calcification, the deposition of minerals in the cardiovascular system, is a complex pathological process that accompanies aging. It is
Cellular Reprogramming Extends Lifespan, Healthspan in Mice
November 1, 2022
Scientists have shown that continuous low-dose induction of reprogramming factors and a single early life reprogramming treatment both significantly increase lifespan and healthspan in progeroid mice while altering their epigenetic landscape [1]. In vivo reprogramming Cellular reprogramming is the process of treating cells with compounds
Rejuvenation Roundup October 2022
November 1, 2022
Ghouls, goblins, and ghosts were all on display last night, but today, we bring you something even scarier: Aging! Let’s see what’s been done to fight back against aging in October. LEAF News Team and activities Leading the Movement for Longer and Healthier Lives: As a
Vitamin D Combats Oxidative Stress in Gingival Cells
October 31, 2022
A cellular study published in the Journal of Dental Sciences has shown that Vitamin D alleviates inflammaging related to the oxidative stress brought on by advanced glycation end-products (AGEs). Diabetes and AGEs Previous research has shown that the uncontrolled blood sugars associated with Type 2 diabetes
Turn.bio Announces Preliminary Results of a CAR-T Cell Study
October 28, 2022
Turn.bio has announced that its proprietary cellular reprogramming technology was able to significantly increase the proliferative and cytotoxic potential of premanufactured CAR-T cells in vitro. Turn.bio, a developer of mRNA-based cellular reprogramming technologies, has announced preliminary results from its current trial. The announcement was made by
New Compounds Beat Resveratrol in Sirtuin Activation
October 27, 2022
A recent study published in Molecules has tested multiple thiazole-based derivatives that appear to activate the sirtuin SIRT1 more than resveratrol [1]. Sirtuins Resveratrol, commonly found in grape skins and red wine, generated some of the initial interest in sirtuin activators after initial studies showing many