Tag: Maria Blasco

A team of researchers led by Dr. Maria Blasco of the Spanish National Cancer Research Center has shown that shorter telomeres make mice more susceptible to kidney fibrosis [1]. The new study not only clearly demonstrates this link but also provides mouse models which can be used to study – and perhaps eventually address –...

Back in January 2018, researchers at CNIO reversed lung fibrosis in mice using a single gene therapy. Today, we want to spotlight a new study that builds on the positive results of the 2018 research, taking us another step closer to telomerase gene therapy in humans to reverse pulmonary fibrosis. The road to a gene...

We had the opportunity to interview one of the speakers, Dr. María Blasco, during the conference, and we asked her more about her work with telomeres, telomerase therapy, and aging. Telomere loss is a proposed reason we age Telomere attrition—the wearing out of your chromosomes' protective caps with age—is widely thought to be one of...

Researchers have demonstrated that telomerase gene therapy does not increase the risk of cancer, even in strains of mice that are particularly susceptible to cancer [1]. A tale of telomeres Short telomeres trigger cellular senescence and are thought to be one of the primary hallmarks of aging, which has led to various researchers seeking ways...